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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/ms2023-298.</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-7915</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПРАКТИКА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PRACTICE</subject></subj-group></article-categories><title-group><article-title>Клинические проявления аутоиммунных ревматических заболеваний в гортани</article-title><trans-title-group xml:lang="en"><trans-title>Clinical manifestations of autoimmune rheumatic diseases in the larynx</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1502-6337</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Степанова</surname><given-names>Ю. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Stepanova</surname><given-names>Ju. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Степанова Юлия Евгеньевна, доктор медицинских наук, доцент, заведующий отделом патофизиологии голоса и речи</p><p>190013, Санкт-Петербург, ул. Бронницкая, д. 9</p></bio><bio xml:lang="en"><p>Julia E. Stepanova, Dr. Sci. (Med.), Associate Professor, Head of the Department of Voice and Speech Pathophysiology</p><p>9, Bronnitskaya St., St Petersburg, 190013</p></bio><email xlink:type="simple">julia.stepanov@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8676-3946</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Корень</surname><given-names>Е. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Коren</surname><given-names>E. E</given-names></name></name-alternatives><bio xml:lang="ru"><p>Корень Елена Евгеньевна, научный сотрудник отдела патофизиологии голоса и речи</p><p>190013, Санкт-Петербург, ул. Бронницкая, д. 9</p></bio><bio xml:lang="en"><p>Elena E. Коren, Research Officer of the Department of Voice and Speech Pathophysiology</p><p>9, Bronnitskaya St., St Petersburg, 190013</p></bio><email xlink:type="simple">ekoren@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Санкт-Петербургский научно-исследовательский институт уха, горла, носа и речи</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint Petersburg Research Institute of Ear, Throat, Nose and Speech</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>18</day><month>11</month><year>2023</year></pub-date><volume>0</volume><issue>19</issue><fpage>172</fpage><lpage>179</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Степанова Ю.Е., Корень Е.Е., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Степанова Ю.Е., Корень Е.Е.</copyright-holder><copyright-holder xml:lang="en">Stepanova J.E., Коren E.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/7915">https://www.med-sovet.pro/jour/article/view/7915</self-uri><abstract><sec><title>Введение</title><p>Введение. Аутоиммунные ревматические заболевания развиваются во многих органах и системах, в т. ч. гортани. Жалобы на нарушение голосовой функции у пациентов с данной патологией требуют тщательного клинико-эндоскопического анализа. Цель. Определить клиническо-эндоскопические изменения гортани у пациентов с нарушениями голосовой функции при аутоиммунных ревматических заболеваниях.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В фониатрическое отделение ФГБУ СПб НИИ ЛОР обратился 31 (100%) пациент в возрасте от 25 до 84 (41 ± 15) лет с аутоиммунными ревматическими заболеваниями. Мужчин – 3 (10%), женщин – 28 (90%). Все больные жаловались на нарушение голосовой функции, 5 обследованных (16%) беспокоило нарушение дыхания при физической нагрузке или в покое. Пациенты были объединены в 3 группы: системная красная волчанка – 4 (13%) человека, системные васкулиты – 10 (32%) человек, ревматоидный артрит – 17 (55%) человек.</p><p>Для постановки диагноза использовали видеоларингоскопию, видеоларингостробоскопию, аутофлюоресцентную эндоскопию, NBI-эндоскопию (по показаниям).</p></sec><sec><title>Результаты и обсуждение</title><p>Результаты и обсуждение. Распределение патологии гортани по нозологическим формам у больных с аутоиммунными ревматическими заболеваниями было следующим. Самыми многочисленными оказались группы с функциональной дисфонией по гипотонусному типу – 10 (32%) и бамбуковыми узелками – 8 (26%) пациентов. Хронические стенозы гортани диагностировали у 5 (16%), хронический катаральный ларингит и мягкие узелки голосовых складок у 3 (9,5%) человек в каждой группе соответственно. Наименьшее количество пациентов страдало язвенно-некротическими состояниям гортани и глотки – 2 (7%). Выводы. Изменения гортани при аутоиммунных ревматических заболеваниях имели как специфические проявления, так и неспецифические. К последним относят функциональную дисфонию по гипотонусному типу, хронический катаральный ларингит, мягкие узелки голосовых складок. Специфическими для пациентов с аутоиммунными ревматическими заболеваниями были бамбуковые узелки голосовых складок, язвенно-некротические заболевания, хронические стенозы гортани (инфильтративные и рубцовые).</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Autoimmune rheumatic diseases are attributed to a systemic process that develops in many organs, including the larynx. Complaints of impaired vocal function in patients with this pathology require a thorough clinical and endoscopic analysis.</p></sec><sec><title>The purpose of the study</title><p>The purpose of the study. To determine the clinical-endoscopic changes of the larynx in patients with impaired vocal function in autoimmune rheumatic diseases..</p></sec><sec><title>Materials and methods</title><p>Materials and methods. 31 (100%) patients aged 25 to 84 (41 ± 15) years with autoimmune rheumatic diseases applied to the phoniatric department of the St. Petersburg Research Institute of ENT. There were 3 men (10%), 28 women (90%). All patients complained of impaired vocal function, 5 of the examined (16%) were also concerned about breathing disorders during exercise or at rest.</p><p>Patients were grouped into three groups: systemic lupus erythematosus 4 (13%) people, systemic vasculitis 10 (32%) people, rheumatoid arthritis 17 (55%) people.</p><p>Videolaryngoscopy, videolaryngostroboscopy, autofluorescence endoscopy, NBI – endoscopy (according to indications) were used to make the diagnosis.</p></sec><sec><title>Results</title><p>Results. The distribution of laryngeal pathology by nosological forms in patients with аutoimmune rheumatic diseases was as follows. The most numerous were groups with functional dysphonia of the hypotonic type 10 (32%) and bamboo nodules of 8 (26%) patients. Chronic laryngeal stenosis was diagnosed in 5 (16%), and chronic catarrhal laryngitis and soft nodules of the vocal folds in 3 (9.5%) people in each group (respectively). The smallest number of patients suffered from ulcerative necrotic changes of the larynx and pharynx – 2 (7%).</p></sec><sec><title>Conclusion</title><p>Conclusion. Thus, laryngeal changes in аutoimmune rheumatic diseases had both specific manifestations and non-specific ones. The latter include functional dysphonia of the hypotonic type, chronic catarrhal laryngitis, soft nodules of the vocal folds. Bamboo nodules of the vocal folds, ulcerative necrotic diseases, chronic laryngeal stenosis (infiltrative and scarring) were specific for patients with аutoimmune rheumatic diseases.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>васкулиты</kwd><kwd>гранулематоз Вегенера</kwd><kwd>гранулематоз с полиангиитом</kwd><kwd>бамбуковые узелки голосовых складок</kwd><kwd>дисфония</kwd><kwd>осиплость</kwd></kwd-group><kwd-group xml:lang="en"><kwd>vasculitis</kwd><kwd>Wegener’s granulomatosis</kwd><kwd>granulomatosis with polyangiitis</kwd><kwd>bamboo nodules of the vocal folds</kwd><kwd>dysphonia</kwd><kwd>hoarseness</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Насонов ЕЛ, Александрова ЕН, Новиков АА. Аутоиммунные ревматические заболевания – проблемы иммунопатологии и персонифицированной терапии. 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