medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/ms2023-406medsovet-7919Research ArticleCOVID-19Возможные перспективы применения фитоадаптогенов в постковидном периодеPossible perspectives for using phytoadaptogens in post-COVID periodhttps://orcid.org/0000-0003-3164-9737СаньковаМ. В.SankovaM. V.

Санькова Мария Вячеславовна, стажер-исследователь

119991, Москва, ул. Трубецкая, д. 8, стр. 2

Maria V. Sankova, Research Assistant

8, Bldg. 2, Trubetskaya St., Moscow, 119991

cankov@yandex.ruhttps://orcid.org/0000-0003-3541-6041МеситскаяД. Ф.MesitskayaD. F.

Меситская Динара Фератовна, кандидат медицинских наук, врач-кардиолог

119991, Москва, ул. Трубецкая, д. 8, стр. 2

Dinara F. Mesitskaya, Cand. Sci. (Med.), Cardiologist

8, Bldg. 2, Trubetskaya St., Moscow, 119991

aranid980@gmail.comhttps://orcid.org/0000-0002-0276-7374АндреевД. А.AndreevD. A.

Андреев Денис Анатольевич, доктор медицинских наук, профессор, врач-кардиолог, заведующий кафедрой кардиологии, функциональной и ультразвуковой диагностики

119991, Москва, ул. Трубецкая, д. 8, стр. 2

Denis A. Andreev, Dr. Sci. (Med.), Professor, Cardiologist, Head of Department of Cardiology, Functional and Ultrasound Diagnostic

8, Bldg. 2, Trubetskaya St., Moscow, 119991

dennan@mail.ruhttps://orcid.org/0000-0003-0658-0520СаньковА. В.SankovA. V.

Саньков Алексей Вячеславович, студент

119991, Москва, ул. Трубецкая, д. 8, стр. 2

Aleksey V. Sankov, Student

8, Bldg. 2, Trubetskaya St., Moscow, 119991

A.V.Sankov@yandex.ruПервый Московский государственный медицинский университет имени И.М. Сеченова (Сеченовский Университет)РоссияSechenov First Moscow State Medical University (Sechenov University)Russian Federation202318112023020190198Copyright © Санькова М.В., Меситская Д.Ф., Андреев Д.А., Саньков А.В., 20232023Санькова М.В., Меситская Д.Ф., Андреев Д.А., Саньков А.В.Sankova M.V., Mesitskaya D.F., Andreev D.A., Sankov A.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/7919

В настоящее время новая коронавирусная инфекция, вызванная SARS-CoV-2, остается серьезной проблемой общественного здравоохранения. Борьба с данным вирусом включает постоянный поиск не только оптимального лечения самого заболевания, но и возможностей полноценной реабилитации пациентов в постковидном периоде. Учитывая вариативность клинических проявлений и необходимость одномоментной коррекции функций многих систем и органов после данного заболевания, представляется целесообразным использование в восстановлении этих пациентов растительных адаптогенов, которые характеризуются многоплановым воздействием на организм. Проведенный нами обзор свидетельствует об уникальности фитоадаптогенов, заключающейся в их мягком разнонаправленном воздействии на нейроэндокринно-иммунную регуляцию, которое приводит к восстановлению нарушенных во время заболевания физиологических функций. Было показано, что растительные адаптогены способствуют уменьшению патологических изменений в легких, обладают антигипоксическим и антиоксидантным эффектом, проявляют психотропные и нейропротекторные свойства, влияют на углеводный обмен и деятельность сердечно-сосудистой системы, поддерживают иммунный гомеостаз и оказывают общее адаптогенное действие. Кроме того, эти биопрепараты усиливают эффективность всей комплексной терапии и позволяют нивелировать побочные эффекты совместно принимаемых синтетических лекарственных препаратов. Для достижения оптимального воздействия фитоадаптогенов у переболевших COVID-19 пациентов предпочтительнее использовать комбинации адаптогенных растений с учетом наличия взаимоусиливающих фармакологических свойств растений и ведущих патогномоничных синдромов. Использование фитоадаптогенов в лечении пациентов постковидного периода будет способствовать их психоэмоциональной стабилизации, повышению иммунорезистентности, регрессии патологических изменений в органах и тканях, улучшению умственной и физической работоспособности, что в итоге позволит улучшить качество жизни переболевших COVID-19 пациентов и сохранить общественное здоровье.

Currently the new coronavirus infection caused by SARS-CoV-2 continues to be a serious public health problem. The fight against this virus includes a continuous search not only for the optimal treatment of the disease itself, but also for the full rehabilitation of patients in the postcovid period. Given the clinical variability and the need for one-stage correcting functions of many systems and organs after this disease, it seems appropriate to use in the recovery of these patients plant adaptogens, which have multiple effects on the body. Our review demonstrates the phytoadaptogen uniqueness in their mild multidirectional impact on neuroendocrine-immune regulation, which leads to the correcton of physiological functions disturbed during the disease. Plantl adaptogens were shown to help reduce pathological changes in the lungs, have antihypoxic and antioxidant effects, exhibit psychotropic and neuroprotective properties, influence on carbohydrate metabolism and cardiovascular system activity, support immune homeostasis and have a general adaptogenic effect. In addition, these biologics enhance the effectiveness of the entire complex therapy and allow neutralizing the side effects of the jointly taken synthetic drugs. To achieve the optimal effect of phytoadaptogens in post-COVID-19 patients it is preferable to use adaptogenic plant combinations, taking into account the mutually reinforcing pharmacological plant properties and leading pathognomonic syndromes. The phytoadaptogen use in the post-COVID-19 patient treatment will contribute to their psychoemotional stabilization, immunoresistance increase, pathological change regression in organs and tissues, mental and physical performance improvement, which will eventually improve the life quality of recovered from COVID-19 patients and preserve public health.

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The authors declare that there are no conflicts of interest present.