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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/ms2023-488</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-8084</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>БРОНХОПУЛЬМОНОЛОГИЯ И ОТОЛАРИНГОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>BRONCHOPULMONOLOGY, OTORHINOLARYNGOLOGY</subject></subj-group></article-categories><title-group><article-title>Обеспеченность витаминами (А, Е, D, С, В6, В12) и минеральными веществами (Zn, Fe, Mg, Ca, P)  детей с рекуррентными респираторными инфекциями и коррекция их дефицита как возможность профилактики частых респираторных инфекций</article-title><trans-title-group xml:lang="en"><trans-title>Supply of vitamins (A, E, D, C, B6, B12) and mineral substances (ZN, FE, MG, CA, P) for children with recurrent respiratory infections  and deficiency correction of their deficiency as a possibility to prevent frequent respiratory infections</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3261-1143</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сафина</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Safina</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Сафина Асия Ильдусовна, д.м.н., профессор, заслуженный врач РТ, заведующий кафедрой педиатрии и неонатологии имени профессора Е.М. Лепского</p><p>420012, Казань, ул. Бутлерова, д. 36</p></bio><bio xml:lang="en"><p>Asiya I. Safina, Dr. Sci. (Med.), Professor, Head of the Department of Pediatrics and Neonatology named after Professor E.M. Lepsky</p><p>36, Butlerov St., Kazan, 420012</p></bio><email xlink:type="simple">safina_asia@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2611-1580</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Закиров</surname><given-names>И. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Zakirov</surname><given-names>I. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Закиров Ильнур Илгизович, к.м.н., доцент, доцент кафедры педиатрии и неонатологии имени профессора Е.М. Лепского; заведующий кафедрой клинической диагностики с курсом педиатрии</p><p>420012, Казань, ул. Бутлерова, д. 36</p><p>420012, Казань, ул. Кремлевская, д. 18</p></bio><bio xml:lang="en"><p>Ilnur I. Zakirov, Cand. Sci. (Med.), Associate Professor, Associate Professor of the Department of Pediatrics and Neonatology named after Professor E.М. Lepsky; Head of the Department of Clinical Diagnostics with a Course in Pediatrics</p><p>36, Butlerov St., Kazan, 420012</p><p>18, Kremlevskaya St., Kazan, 420012</p></bio><email xlink:type="simple">zakirov.ilnur@inbox.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3780-5243</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мансурова</surname><given-names>Г. Ш.</given-names></name><name name-style="western" xml:lang="en"><surname>Mansurova</surname><given-names>G. Sh.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Мансурова Гюзель Шамильевна, к.м.н., доцент, доцент кафедры педиатрии и неонатологии имени профессора Е.М. Лепского; доцент, кафедра клинической диагностики с курсом педиатрии</p><p>420012, Казань, ул. Бутлерова, д. 36</p><p>420012, Казань, ул. Кремлевская, д. 18</p></bio><bio xml:lang="en"><p>Gyuzel Sh. Mansurova, Cand. Sci. (Med.), Associate Professor, Associate Professor of the Department of Pediatrics and Neonatology named after Professor E.М. Lepsky; Associate Professor, Department of Clinical Diagnostics with a Course in Pediatrics</p><p>36, Butlerov St., Kazan, 420012</p><p>18, Kremlevskaya St., Kazan, 420012</p></bio><email xlink:type="simple">gsm98@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8052-2620</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юсупова</surname><given-names>Н. З.</given-names></name><name name-style="western" xml:lang="en"><surname>Yusupova</surname><given-names>N. Z.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Юсупова Наиля Зуфаровна, д.м.н., профессор, заведующий кафедрой общей гигиены</p><p>420012, Казань, ул. Бутлерова, д. 36</p></bio><bio xml:lang="en"><p>Nailya Z. Yusupova, Dr. Sci. (Med.), Professor, Head of the Department of General Hygiene</p><p>36, Butlerov St., Kazan, 420012</p></bio><email xlink:type="simple">nelya321@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-3821-9452</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Искандирова</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Iskandirova</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Искандирова Вероника Алексеевна, ординатор, кафедра педиатрии и неонатологии имени профессора Е.М. Лепского</p><p>420012, Казань, ул. Бутлерова, д. 36</p></bio><bio xml:lang="en"><p>Veronika A. Iskandirova, Resident, Department of Pediatrics and Neonatology named after Professor E.М. Lepsky</p><p>36, Butlerov St., Kazan, 420012</p></bio><email xlink:type="simple">dr.iskandirova@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Казанская государственная медицинская академия – филиал Российской медицинской академии непрерывного профессионального образования</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Continuing Professional Education</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Казанская государственная медицинская академия – филиал Российской медицинской академии непрерывного профессионального образования; Казанский (Приволжский) федеральный университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Continuing Professional Education; Kazan (Volga region) Federal University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>26</day><month>02</month><year>2024</year></pub-date><volume>0</volume><issue>1</issue><elocation-id>98–106</elocation-id><permissions><copyright-statement>Copyright &amp;#x00A9; Сафина А.И., Закиров И.И., Мансурова Г.Ш., Юсупова Н.З., Искандирова В.А., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Сафина А.И., Закиров И.И., Мансурова Г.Ш., Юсупова Н.З., Искандирова В.А.</copyright-holder><copyright-holder xml:lang="en">Safina A.I., Zakirov I.I., Mansurova G.S., Yusupova N.Z., Iskandirova V.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/8084">https://www.med-sovet.pro/jour/article/view/8084</self-uri><abstract><sec><title>Введение</title><p>Введение. Рекуррентные респираторные инфекции у детей являются актуальной проблемой педиатрии. Для поддержания и функционирования иммунной системы у детей важное значение отводится их обеспеченности витаминами и минеральными веществами.</p></sec><sec><title>Цель</title><p>Цель. Оценить обеспеченность детей с рекуррентными респираторными инфекциями витаминами (А, Е, D, С, В6, В12, фолиевая кислота) и минеральными веществами (Zn, Fe, Mg, Ca, P) и провести коррекцию их дефицита витаминно-минеральным комплексом.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Исследование проведено с участием 65 детей в возрасте от 3 до 8 лет в 2 группах: 1-я группа – дети с рекуррентными респираторными инфекциями, n = 50; 2-я группа – контрольная, n = 15. Проведено амбулаторное обследование, анкетирование родителей и исследование крови на витамины (А, Е, D, С, В6, В12, фолиевая кислота) и минеральные вещества (Zn, Fe, Mg, Ca общий, Са++, P). 30 детям с рекуррентными респираторными инфекциями был назначен витаминно-минеральный комплекс по 1 табл. 2 раза в день с оценкой витаминно-минеральной обеспеченности и частоты респираторных инфекций после окончания приема.</p></sec><sec><title>Результаты</title><p>Результаты. У всех обследованных детей как в основной, так и в контрольной группах наиболее распространенными были дефицит жирорастворимых витаминов D (69%), А (40%), Е (35%) и минералов Zn (70%) и Fe (44%). У детей с рекуррентными респираторными инфекциями дефицит витаминов D, А и Zn встречался чаще, чем в контрольной группе (р &lt; 0,05), в 96% случаев он был комбинированный, в виде сочетанного дефицита жирорастворимых витаминов D, А, Е и минералов Zn, Fe (66% случаев). Прием витаминно-минерального комплекса способствовал улучшению показателей витаминно-минеральной обеспеченности и снижению респираторной заболеваемости в последующие 2 мес. после окончания приема препарата.</p></sec><sec><title>Заключение</title><p>Заключение. «NOW Детские витамины "Ягодный взрыв"» может с успехом использоваться для поддержания витаминно-минеральной обеспеченности и снижения респираторной заболеваемости у детей с рекуррентными респираторными инфекциями. </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Recurrent respiratory infections in children are a pressing problem in pediatrics. To maintain and function the immune system in children, their provision of vitamins and minerals is important.</p></sec><sec><title>Purpose</title><p>Purpose. To assess the provision of children with recurrent respiratory infections with vitamins (A, E, D, C, B6, B12, folic acid) and minerals (Zn, Fe, Mg, Ca, P) and to correct their deficiency with a vitamin-mineral complex.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The study was conducted on 65 children aged 3 to 8 years in 2 groups of children: group 1, children with RID, n = 50; group 2 – control, n = 15). An outpatient examination, a parent survey and a blood test for vitamins (A, E, D, C, B6, B12, folic acid) and minerals (Zn, Fe, Mg, total Ca, Ca++, P) were carried out. 30 children with RID were prescribed the vitamin and mineral complex, 1 tablet 2 times a day, with an assessment of vitamin and mineral sufficiency and the frequency of respiratory infections after the end of the dose.</p></sec><sec><title>Results</title><p>Results. In all examined children, both in the main and control groups, the most common were deficiencies of fat-soluble vitamins D (69%), A (40%), E (35%) and the minerals Zn (70%) and Fe (44%). In children with RID, deficiency of vitamins D, A and Zn was more common than in the control group (p &lt; 0.05), in 96% of cases it was combined, more often in the form of a combined deficiency of fat-soluble vitamins D, A, E and minerals Zn, Fe (66% of cases). Taking vitamin-mineral complex in the 2nd prophylactic dose for 1 month contributed to an improvement in vitamin and mineral sufficiency and a decrease in respiratory morbidity in the next 2 months after stopping the drug.</p></sec><sec><title>Conclusion</title><p>Conclusion. Vitamin-mineral complex can be successfully used to maintain vitamin and mineral levels and reduce respiratory morbidity in children with recurrent respiratory infections.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>рецидивирующие респираторные инфекции</kwd><kwd>профилактика</kwd><kwd>дети</kwd><kwd>коррекция витаминно-минеральной недостаточности</kwd><kwd>иммунный ответ</kwd></kwd-group><kwd-group xml:lang="en"><kwd>recurrent respiratory infections</kwd><kwd>prevention</kwd><kwd>children</kwd><kwd>correction of vitamin and mineral deficiency</kwd><kwd>immune response</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Chiappini E, Santamaria F, Marseglia GL, Marchisio P, Galli L, Cutrera R et al. Prevention of recurrent respiratory infections. Inter-society Consensus. 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