medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/ms2024-193medsovet-8313Research ArticleФУНКЦИОНАЛЬНЫЕ ЗАБОЛЕВАНИЯ ЖКТFUNCTIONAL GASTROINTESTINAL DISEASESРаспространенность и факторы риска функциональных абдоминальных расстройств по данным опросного исследования у молодежиPrevalence and risk factors of functional abdominal disorders according to a survey study among young peoplehttps://orcid.org/0000-0002-6505-1031ЖестковаТ. В.ZhestkovaT. V.

Жесткова Татьяна Васильевна, к.м.н., доцент, доцент кафедры пропедевтики внутренних болезней, 

390026, Рязань, ул. Высоковольтная, д. 9

Tatyana V. Zhestkova, Cand. Sci. (Med.), Associate Professor of the Department of Propaedeutic Internal Diseases, 

9, Vysokovoltnaya St., Ryazan, 390026

t-zhestkova@bk.ruРязанский государственный медицинский университет имени академика И.П. ПавловаРоссияRyazan State Medical UniversityRussian Federation202404062024081218Copyright © Жесткова Т.В., 20242024Жесткова Т.В.Zhestkova T.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/8313Введение

Введение. Этиологические аспекты функциональной диспепсии (ФД) и синдрома раздраженного кишечника (СРК) не ясны, эпидемиология заболеваний в возрастных группах и социумах может помочь в понимании стартовых причин патологии.

Цель

Цель. Оценить факторы риска развития и распространенность абдоминальных симптомов, характерных для ФД и СРК, среди активных пользователей интернет-сообществ.

Материалы и методы

Материалы и методы. Проведен анонимный онлайн-опрос среди студентов медицинского университета. Анкета содержала вопросы о характерных для ФД и СРК жалобах за последнюю неделю, «тревожных» симптомах, личностных характеристиках респондента и возможных факторах риска: курение, семейный анамнез, прием антибиотиков, препаратов железа, нестероидных противовоспалительных средств (НПВС).

Результаты

Результаты. В исследование включено 983 респондента в возрасте 18−26 лет, 279 мужчин и 704 женщины. Симптомы неисследованных регулярных (>1 раза в нед.) постпрандиальных диспепсических расстройств, вздутия живота и абдоминальной боли выявлены у 391 (39,8%) человека, из них 29% мужчин и 44% женщин (p < 0,001). Факторами риска для регулярных неисследованных расстройств было наличие родственников с хроническими заболеваниями желудочно-кишечного тракта (ОШ 2,05 [1,56; 2,70]), женский пол (ОШ 1,92 [1,43; 2,59]), прием НПВС (ОШ 1,48 [1,14; 1,91]), для женщин − курение (ОШ 2,24 [1,57; 3,18]). Критериям ФД соответствовало 6,5% респондентов, из них с изолированной эпигастральной болью − 23,4%, изолированным постпрандиальным дистресс-синдромом – 26,6%, сочетанным вариантом ФД − 50% чело век. Критериям СРК соответствовало 2,5% респондентов, из которых у 64% был overlap-синдром с ФД. Наличие ФД было связано с приемом НПВС: r = 0,081; p = 0,011 (ОШ 1,95 [1,16; 3,30]).

Выводы

Выводы. Распространенность ФД и/или СРК среди лиц 18−26 лет составляет 7,4% без достоверных различий среди мужчин и женщин. Прием НПВС может рассматриваться как фактор, способствующий развитию ФД.

Introduction

Introduction. The etiological aspects of functional dyspepsia (FD) and irritable bowel syndrome (IBS) are not clear; the epidemiology of diseases in age groups and societies can help in understanding the starting causes of the pathology.

Aim

Aim. To assess the risk factors for the development and prevalence of abdominal symptoms characteristic of FD and IBS among active users of Internet communities.

Materials and methods

Materials and methods. An anonymous online survey was conducted among medical university students. The questionnaire contains questions about complaints typical of FD and IBS over the past week, “alarm” symptoms, personal characteristics of the respondent and possible risk factors: smoking, family history, taking antibiotics, iron pills, non-steroidal anti-inflammatory drugs (NSAIDs).

Results and discussion

Results and discussion. The study included 983 respondents aged 18−26 years, 279 men and 704 women. Symptoms of unstudied regular (>1 time per week) postprandial dyspeptic disorders, bloating and abdominal pain were identified in 391 (39.8%) people, of which 29% were men and 44% were women (p < 0.001). Risk factors for regular unstudied disorders were having relatives with chronic gastrointestinal diseases (OR 2.05 [1.56, 2.70]); female gender (OR 1.92 [1.43, 2.59]); taking NSAIDs (OR 1.48 [1.14; 1.91]); for women – smoking (OR 2.24 [1.57; 3.18]). 6.5% of respondents met the criteria for FD, of which 23.4% had isolated epigastric pain, 26.6% had isolated postprandial distress syndrome, and 50% had combined FD. 2.5% of respondents met the criteria for IBS, 64% of whom had overlap syndrome with FD. The presence of FD was associated with NSAIDs use: r = 0.081; p = 0.011 (OR 1.95 [1.16; 3.30]).

Conclusions

Conclusions. The prevalence of FD and/or IBS among people aged 18−26 years is 7.4%, with no significant differences between men and women. Taking NSAIDs can be considered as a factor contributing to the development of FD.

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The authors declare that there are no conflicts of interest present.