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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/ms2024-185</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-8336</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ХРОНИЧЕСКИЕ ЗАБОЛЕВАНИЯ ЛЕГКИХ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CHRONIC PULMONARY DISEASES</subject></subj-group></article-categories><title-group><article-title>Эффективность длительной респираторной поддержки у пациентки после пульмонэктомии</article-title><trans-title-group xml:lang="en"><trans-title>The effectiveness of long-term respiratory support in a patient after pneumonectomy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5804-8643</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мукатова</surname><given-names>И. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Mukatova</surname><given-names>I. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мукатова Ирина Юрьевна - д.м.н., профессор кафедры внутренних болезней с курсом нефрологии, гематологии, аллергологии, иммунологии, Медицинский университет Астана.</p><p>010000, Астана, ул. Бейбитшилик, д. 49а</p></bio><bio xml:lang="en"><p>Irina Yu. Mukatova - Dr. Sci. (Med.), Professor of Department of Internal Illnesses with a course of Nephrology, Hematology, Allergology, Immunology, Astana Medical University.</p><p>49a, Beibitshilik St., Astana, 010000</p></bio><email xlink:type="simple">mukatovair@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-7864-2399</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Серикова</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Serikova</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Серикова Аурини Сериковна - магистр медицины, пульмонолог, Многопрофильный медицинский центр Green Clinic.</p><p>020000, Астана, ул. Хусейн Бен Талал, д. 25/1</p></bio><bio xml:lang="en"><p>Aurini S. Serikova - Master of Medicine, Pulmononlogist, Multidisciplinary Medical Center Green Clinic.</p><p>25/1, Hussein Bin Talal St., Astana, 020000</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4726-4906</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нуралиева</surname><given-names>Г. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Nuralieva</surname><given-names>G. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Нуралиева Галиа Сериковна - к.м.н., доцент кафедры пульмонологии, ПМГМУ им. И.М. Сеченова (Сеченовский Университет); научный сотрудник лаборатории интенсивной терапии и дыхательной недостаточности, НИИ пульмонологии ФМБА.</p><p>119991, Москва, ул. Трубецкая, д. 8, стр. 2; 115682, Москва, Ореховый бульвар, д. 28</p></bio><bio xml:lang="en"><p>Galiya S. Nuralieva - Cand. Sci. (Med.), Associate Professor, Department of Pulmonology, Sechenov First Moscow State Medical University (Sechenov University); Researcher, Laboratory of Intensive Therapy and Respiratory Failure, Research Institute for Pulmonology of the Federal Medical Biological Agency.</p><p>8, Bldg. 2, Trubetskaya St., Moscow, 119991; 8, Orekhovy Boulevard, Moscow, 115682</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5999-2150</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Авдеев</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Avdeev</surname><given-names>S. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Авдеев Сергей Николаевич - академик РАН, д.м.н., профессор, заведующий кафедрой пульмонологии, ПМГМУ им. И.М. Сеченова (Сеченовский Университет); руководитель клинического отдела, НИИ пульмонологии ФМБА.</p><p>119991, Москва, ул. Трубецкая, д. 8, стр. 2; 115682, Москва, Ореховый бульвар, д. 28</p></bio><bio xml:lang="en"><p>Sergey N. Avdeev - Acad. RAS, Dr. Sci. (Med.), Professor, Head of Department of Pulmonology, Sechenov First Moscow State Medical University (Sechenov University); Head of the Clinical Department, Research Institute for Pulmonology of the Federal Medical Biological Agency.</p><p>8, Bldg. 2, Trubetskaya St., Moscow, 119991; 8, Orekhovy Boulevard, Moscow, 115682</p></bio><email xlink:type="simple">serg_avdeev@list.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Медицинский университет Астана</institution><country>Казахстан</country></aff><aff xml:lang="en"><institution>Astana Medical University</institution><country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Многопрофильный медицинский центр Green Clinic</institution><country>Казахстан</country></aff><aff xml:lang="en"><institution>Multidisciplinary Medical Center Green Clinic</institution><country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Первый Московский государственный медицинский университет имени И.М. Сеченова (Сеченовский Университет); Научно-исследовательский институт пульмонологии Федерального медико-биологического агентства</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Sechenov First Moscow State Medical University (Sechenov University); Research Institute for Pulmonology of the Federal Medical Biological Agency</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>06</day><month>06</month><year>2024</year></pub-date><volume>0</volume><issue>9</issue><fpage>87</fpage><lpage>91</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мукатова И.Ю., Серикова А.С., Нуралиева Г.С., Авдеев С.Н., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Мукатова И.Ю., Серикова А.С., Нуралиева Г.С., Авдеев С.Н.</copyright-holder><copyright-holder xml:lang="en">Mukatova I.Y., Serikova A.S., Nuralieva G.S., Avdeev S.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/8336">https://www.med-sovet.pro/jour/article/view/8336</self-uri><abstract><p>Респираторная поддержка при хронической дыхательной недостаточности в последние десятилетия широко применяется чаще всего у пациентов с ХОБЛ в терминальной стадии. Доказано, что развитие хронической гиперкапнической дыхательной недостаточности сопряжено с учащением обострений, повышением потребности в госпитализации, укорочением времени до возникновения следующей декомпенсации. Гиперкапния является определяющим фактором смертности. Неинвазивная вентиляция легких является эффективным методом лечения гиперкапнической дыхательной недостаточности. Длительная неинвазивная вентиляция легких улучшает дневную гиперкапнию, качество жизни, увеличивает период до следующего тяжелого обострения и выживаемость пациентов с ХОБЛ. Пациенты с ХОБЛ имеют различные фенотипы и различные коморбидные заболевания, что создает сложности в выборе респираторной поддержки и оценке эффективности данного метода лечения. В доступной литературе практически нет данных по длительной неинвазивной респираторной поддержке пациентов с ХОБЛ после пульмонэктомии. Имеются преимущественно публикации о неинвазивной вентиляции легких в раннем послеоперационном периоде после пульмонэктомии. Цель данной публикации – представить клинический случай успешной комбинированной респираторной поддержки в виде длительной неинвазивной вентиляции легких совместно с кислородотерапией у пациентки с ХОБЛ и бронхоэктазами единственного легкого. Отражены этапы ведения гипоксемической и в последующем гиперкапнической хронической дыхательной недостаточности. Продемонстрирован опыт успешной длительной амбулаторной неинвазивной вентиляции у пациентки с хронической гиперкапнической дыхательной недостаточностью в исходе ХОБЛ и пульмонэктомии. Данное наблюдение показало возможность применения комбинированной респираторной поддержки в амбулаторных условиях у коморбидного пациента с ХОБЛ единственного легкого и пульмонэктомией в анамнезе.</p></abstract><trans-abstract xml:lang="en"><p>Respiratory support for chronic respiratory failure in the last stages is widely used, most often in patients with end-stage COPD. It has been proven that the development of chronic hypercapnic respiratory failure is associated with an increasing in exacerbations, increased hospitalization rates, and an acceleration of the time before subsequent decompensation. Also hypercapnia is</p><p>a determining factor in mortality. Effective treatment method of hypercapnic insufficiency is non-invasive ventilation. Long-term non-invasive ventilation improves daytime hypercapnia, quality of life, increases the period until the next severe exacerbation and survival of patients with COPD. Patients with COPD have different phenotypes and various comorbid diseases, which which may be challenging while choosing method of respiratory support and assessing the effectiveness of this treatment method. There is lack of data on long-term non-invasive respiratory support for patients with COPD after pneumonectomy in chronic period. Most of publications dedicated for early post-operative period after pneumonectomy. The purpose of this publication is to present a case of successful long-term non-invasive ventilation combined with oxygen therapy in a patient with COPD and bronchiectasis of a single lung. Stages of management of hypoxemic and subsequently developed hypercapnic chronic respiratory failure are reflected. We demonstrate experience of successful long-term ambulatory non-invasive ventilation in a patient with chronic hypercapnic respiratory failure as a result of COPD and pneumonectomy was demonstrated. Observation study showed feasibility of combined respiratory support in outpatient settings for patient with COPD of a single lung and a history of pneumonectomy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дыхательная недостаточность</kwd><kwd>неинвазивная вентиляция легких</kwd><kwd>хроническая обструктивная болезнь легких</kwd><kwd>пульмонэктомия</kwd><kwd>BiPAP-терапия</kwd><kwd>кислородотерапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>respiratory failure</kwd><kwd>noninvasive ventilation</kwd><kwd>chronic obstructive pulmonary disease</kwd><kwd>pneumonectomy</kwd><kwd>BiPAP</kwd><kwd>oxygen therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Cedano S, Bettencourt AR, Traldi F, Machado MC, Belasco AG. Quality of life and burden in carers for persons with chronic obstructive pulmonary disease receiving oxygen therapy. 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