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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/ms2024-300</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-8493</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПРАКТИКА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PRACTICE</subject></subj-group></article-categories><title-group><article-title>Коморбидность болезней органов дыхания и заболеваний пародонта</article-title><trans-title-group xml:lang="en"><trans-title>Comorbidity of respiratory diseases and periodontal diseases</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1597-1876</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трухан</surname><given-names>Д. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Trukhan</surname><given-names>D. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Трухан Дмитрий Иванович - д.м.н., доцент, профессор кафедры поликлинической терапии и внутренних болезней.</p><p>644043, Омск, ул. Ленина, д. 12</p></bio><bio xml:lang="en"><p>Dmitry I. Trukhan - Dr. Sci. (Med.), Associate Professor, Professor of the Chair of Polyclinic Therapy and Internal Diseases, Omsk State Medical University.</p><p>12, Lenin St., Omsk, 644043</p></bio><email xlink:type="simple">dmitry_trukhan@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сулимов</surname><given-names>А. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Sulimov</surname><given-names>A. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сулимов Анатолий Филиппович - д.м.н., профессор, заведующий кафедрой челюстно-лицевой хирургии.</p><p>644043, Омск, ул. Ленина, д. 12</p></bio><bio xml:lang="en"><p>Anatoly F. Sulimov - Dr. Sci. (Med.), Professor, Head of the Department of Maxillofacial Surgery, Omsk State Medical University.</p><p>12, Lenin St., Omsk, 644043</p></bio><email xlink:type="simple">afsulimov@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4721-6605</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трухан</surname><given-names>Л. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Trukhan</surname><given-names>L. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Трухан Лариса Юрьевна - к.м.н., врач-стоматолог.</p><p>644043, Омск, ул. Ленина, д. 12</p></bio><bio xml:lang="en"><p>Larisa Yu. Trukhan - Cand. Sci. (Med.), Dentist, Omsk State Medical University.</p><p>12, Lenin St., Omsk, 644043</p></bio><email xlink:type="simple">larissa_trukhan@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Омский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Omsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>01</day><month>09</month><year>2024</year></pub-date><volume>0</volume><issue>13</issue><fpage>270</fpage><lpage>278</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Трухан Д.И., Сулимов А.Ф., Трухан Л.Ю., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Трухан Д.И., Сулимов А.Ф., Трухан Л.Ю.</copyright-holder><copyright-holder xml:lang="en">Trukhan D.I., Sulimov A.F., Trukhan L.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/8493">https://www.med-sovet.pro/jour/article/view/8493</self-uri><abstract><p>В начале XXI в. сформировалась концепция «пародонтальной медицины», в рамках которой рассматривается двунаправленная связь патологии пародонта с системными заболеваниями организма. Существуют две гипотезы относительно возможности хронической инфекции пародонта способствовать развитию системного воспаления: 1) изменение микробиоценоза полости рта и воспаление пародонта приводят к увеличению бактериальной транслокации в системный кровоток, вызывая циркуляцию медиаторов воспаления и иммунных комплексов в другие органы и системы организма; 2) изменение микробиоценоза полости рта может привести к нарушениям и изменениям микробиома кишечника при пероральном приеме пародонтопатических организмов. Менее изучена взаимосвязь между заболеваниями пародонта и болезнями органов дыхания. Мы провели поиск в информационных базах Pubmed и Scopus статей, опубликованных до 31.01.2024 г., в которых рассматривалась эта взаимосвязь. Близость и непрерывность полости рта и дыхательных путей позволяет микробиому полости рта быть основным определяющим фактором легочного микробиома. Можно выделить и 2 основных пути транслокации пародонтальных бактерий в легкие - аэрогенный и аспирационный. Представленные в обзоре данные позволяют предполагать вероятную двунаправленную связь заболеваний пародонта с внутрибольничной пневмонией, новой коронавирусной инфекцией COVID-19 и ХОБЛ. Взаимосвязь между патологией пародонта и БА можно считать возможной, однако в ряде исследований эта связь не нашла подтверждения, что требует дальнейшего ее изучения. Связь заболеваний пародонта с внебольничной пневмонией практически не изучалась, однако возможна с учетом как прямого взаимодействия микробиоты полости рта и микробиоты по оси «рот - легкие», так и опосредованно по оси «рот - кишечник - легкие». Нехирургическое пародонтологическое лечение, вероятно, эффективно в лечении и профилактике заболеваний органов дыхания. Приведенные в обзоре данные свидетельствуют о важности здоровья пародонта и необходимости профилактики и лечения патологии пародонтита у пациентов пульмонологического профиля.</p></abstract><trans-abstract xml:lang="en"><p>At the beginning of the 21st century, the concept of “periodontal medicine” was formed, within the framework of which the bidirectional connection of periodontal pathology with systemic diseases of the body is considered. There are two hypotheses regarding the possibility of chronic periodontal infection to contribute to the development of systemic inflammation: 1) changes in the microbiocenosis of the oral cavity and periodontal inflammation lead to an increase in bacterial translocation into the systemic bloodstream, causing the circulation of inflammatory mediators and immune complexes to other organs and systems of the body; 2) changes in the microbiocenosis of the oral cavity can lead to disturbances and changes in the intestinal microbiome due to oral intake of periodontopathic organisms. The relationship between periodontal diseases and respiratory diseases has been less studied. We searched the Pubmed and Scopus databases for articles published up to January 31, 2024, that addressed this relationship. The proximity and continuity of the oral cavity and respiratory tract allows the oral microbiome to be a major determinant of the pulmonary microbiome. It is possible to distinguish 2 main ways of translocation of periodontal bacteria into the lungs - aerogenic and aspiration. The data presented in the review suggest a probable bidirectional relationship between periodontal diseases and hospital-acquired pneumonia, the new coronavirus infection COVID-19, and COPD. The relationship between periodontal pathology and BA can be considered possible, but in a number of studies this relationship has not been confirmed, which requires further study. The connection between periodontal diseases and community-acquired pneumonia has practically not been studied, but it is possible, taking into account the direct interaction of the oral microbiota and the microbiota along the mouth-lung axis, and indirectly along the mouth-intestinal-lung axis. Non-surgical periodontal treatment is likely effective in the treatment and prevention of respiratory diseases. The data presented in the review indicate the importance of periodontal health and the need for the prevention and treatment of periodontitis pathology in pulmonary patients.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>болезни пародонта</kwd><kwd>пародонтит</kwd><kwd>пародонтопатические бактерии</kwd><kwd>ось «рот - легкие»</kwd><kwd>пневмония</kwd><kwd>хроническая обструктивная болезнь легких</kwd><kwd>бронхиальная астма</kwd><kwd>новая коронавирусная инфекция COVID-19</kwd><kwd>нехирургическое лечение пародонтита</kwd></kwd-group><kwd-group xml:lang="en"><kwd>periodontal diseases</kwd><kwd>periodontitis</kwd><kwd>comorbidity</kwd><kwd>periodontal bacteria</kwd><kwd>mouth-lung axis</kwd><kwd>pneumonia</kwd><kwd>chronic obstructive pulmonary disease</kwd><kwd>bronchial asthma</kwd><kwd>new coronavirus infection COVID-19</kwd><kwd>non-surgical treatment of periodontitis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Янушевич ОО, Кузьмина ЭМ, Максимовский ЮМ, Малый АЮ, Дмитриева ЛА, Ревазова ЗЭ и др. 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