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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/ms2024-396</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-8706</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>БРОНХОПУЛЬМОНОЛОГИЯ И ОТОЛАРИНГОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>BRONCHOPULMONOLOGY, OTORHINOLARYNGOLOGY</subject></subj-group></article-categories><title-group><article-title>Острый кашель у детей раннего возраста в практике врача-педиатра первичного звена</article-title><trans-title-group xml:lang="en"><trans-title>Acute cough in young children in the practice of a primary care pediatrician</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3261-1143</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сафина</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Safina</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сафина Асия Ильдусовна - д.м.н., профессор, заслуженный врач Республики Татарстан, заведующая кафедрой педиатрии и неонатологии имени профессора Е.М. Лепского.</p><p>420012, Казань, ул. Бутлерова, д. 36</p></bio><bio xml:lang="en"><p>Asiya I. Safina - Dr. Sci. (Med.), Professor, Head of the Department of Pediatrics and Neonatology named after Prof. E.M. Lepsky.</p><p>36, Butlerov St., Kazan, 420012</p></bio><email xlink:type="simple">afina_asia@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Казанская государственная медицинская академия – филиал Российской медицинской академии непрерывного профессионального образования</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kazan State Medical Academy – a branch of the Russian Medical Academy of Continuing Professional Education</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>25</day><month>11</month><year>2024</year></pub-date><volume>0</volume><issue>19</issue><fpage>88</fpage><lpage>93</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сафина А.И., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Сафина А.И.</copyright-holder><copyright-holder xml:lang="en">Safina A.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/8706">https://www.med-sovet.pro/jour/article/view/8706</self-uri><abstract><p>Острый кашель у детей является очень распространенной проблемой, особенно у детей раннего возраста. Примерно от 4,7 до 23,3% всех причин обращения к врачам первичного звена и до 60% всех консультаций связаны с проблемой кашля у детей. Кашель чаще встречается у детей дошкольного возраста, чем у детей старшего возраста. Самой частой причиной острого кашля у детей являются острые респираторно-вирусные инфекции / острый бронхит. Кашляют ≈75% от 0 до 4 лет, болеющих острыми респираторными инфекциями. Тактика врача-педиатра первичного звена – это оценка симптомов заболевания, вызывающего кашель. В пераую очередь исключить риск развития осложнений, например, таких как пневмония. У большинства детей с острым кашлем этиология связана с острой респираторно-вирусной инфекцией и требует только симптоматической терапии (например, жаропонижающих, питьевой режим и назальная ирригация солевыми растворами). Безрецептурные противокашлевые средства малоэффективны в лечении острого кашля и могут вызывать побочные эффекты, поэтому их следует осторожно назначать у детей до 2 лет. Большой интерес сегодня в педиатрии представляют лекарственные фитопрепараты, обладающие эффективностью и безопасностью в лечении острого кашля, например, препараты на основе Hedera helix L. (экстракта листьев плюща). Результаты Кокрановского обзора 2015 г. по анализу 71 рандомизированного клинического испытания использования фитотерапии (пеларгония, эхинацея, плющ, тимьян, первоцвет, эфирные масла, андрографис метельчатый и др.) в лечении кашля у детей с простудой, продемонстрировали убедительные доказательства эффективности препаратов на основе плюща в снижении частоты и тяжести симптомов кашля (ОР 1,40, ДИ 95% 1,23–1,60; p &lt; 0,00001).</p></abstract><trans-abstract xml:lang="en"><p>Acute cough in children is a very common problem, especially in young children. Approximately 4.7 to 23.3% of all causes for visiting primary care physicians and up to 60% of all consultations are related to cough in children. Cough is more common in preschool children than in older children. Acute respiratory viral infections/acute bronchitis is the most common cause of acute cough in children. About 75% of children aged 0 to 4 years with acute respiratory infections have a cough. The therapeutic approach of a primary care paediatrician is to assess the symptoms of the disease causing the cough. Infections that can cause complications, such as pneumonia, should be excluded. In most children with acute cough, the etiology is associated with an acute respiratory viral infection and only requires symptomatic therapy (antipyretics, fluid regimen, and nasal irrigation with saline solutions). Over-the-counter cough suppressants have shown to be ineffective in treating acute cough and can cause side effects, so they should be prescribed with caution in children under 2 years of age. Herbal medicines in paediatrics are agents of great interest today. They have proven efficacy and safety in the treatment of acute cough, for example, Hedera helix L.-based preparations (ivy leaf extract). The 2015 Cochrane review of 71 randomized clinical trials on herbal medicines (pelargonium, echinacea, ivy, thyme, primrose, essential oils, andrographis paniculata, etc.) used for the treatment of cough in children with colds, demonstrated substantial evidence of the effectiveness of ivy-based preparations in reducing the frequency and severity of cough symptoms (OR 1.40, CI 95% 1.23–1.60; p &lt; 0.00001).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>острый кашель</kwd><kwd>дети</kwd><kwd>лечение</kwd><kwd>фитотерапия</kwd><kwd>Hedera helix L.</kwd></kwd-group><kwd-group xml:lang="en"><kwd>acute cough</kwd><kwd>children</kwd><kwd>treatment</kwd><kwd>herbal medicine</kwd><kwd>Hedera helix L.</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Worrall G. Acute cough in adults. Can Fam Physician. 2011;57(1):48–51. Available at: https://pubmed.ncbi.nlm.nih.gov/21252132/.</mixed-citation><mixed-citation xml:lang="en">Worrall G. Acute cough in adults. Can Fam Physician. 2011;57(1):48–51. Available at: https://pubmed.ncbi.nlm.nih.gov/21252132/.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Alsubaie H, Al-Shamrani A, Alharbi AS, Alhaider S. Clinical practice guidelines: Approach to cough in children: The official statement endorsed by the Saudi Pediatric Pulmonology Association (SPPA). Int J Pediatr Adolesc Med. 2015;2(1):38–43. https://doi.org/10.1016/j.ijpam.2015.03.001.</mixed-citation><mixed-citation xml:lang="en">Alsubaie H, Al-Shamrani A, Alharbi AS, Alhaider S. Clinical practice guidelines: Approach to cough in children: The official statement endorsed by the Saudi Pediatric Pulmonology Association (SPPA). Int J Pediatr Adolesc Med. 2015;2(1):38–43. https://doi.org/10.1016/j.ijpam.2015.03.001.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Gibson PG, Chang AB, Glasgow NJ, Holmes PW, Katelaris P, Kemp AS et al. CICADA: Cough in Children and Adults: Diagnosis and Assessment. Australian Cough Guidelines summary statement. Med J Aust. 2010;192(5):265–271. https://doi.org/10.5694/j.1326-5377.2010.tb03504.x.</mixed-citation><mixed-citation xml:lang="en">Gibson PG, Chang AB, Glasgow NJ, Holmes PW, Katelaris P, Kemp AS et al. CICADA: Cough in Children and Adults: Diagnosis and Assessment. Australian Cough Guidelines summary statement. Med J Aust. 2010;192(5):265–271. https://doi.org/10.5694/j.1326-5377.2010.tb03504.x.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Kasi AS, Kamerman-Kretzmer RJ. Cough. Pediatr Rev. 2019;40(4):157–167. https://doi.org/10.1542/pir.2018-0116.</mixed-citation><mixed-citation xml:lang="en">Kasi AS, Kamerman-Kretzmer RJ. Cough. Pediatr Rev. 2019;40(4):157–167. https://doi.org/10.1542/pir.2018-0116.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Shamo’on H, Hawamdah A, Haddadin R, Jmeian S. Detection of pneumonia among children under six years by clinical examination. East Mediterr Health J. 2004;10(4-5):482–487. Available at: https://pubmed.ncbi.nlm.nih.gov/16335638/.</mixed-citation><mixed-citation xml:lang="en">Shamo’on H, Hawamdah A, Haddadin R, Jmeian S. Detection of pneumonia among children under six years by clinical examination. East Mediterr Health J. 2004;10(4-5):482–487. Available at: https://pubmed.ncbi.nlm.nih.gov/16335638/.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Gadomski AM, Aref GH, Hassanian F, el Ghandour S, el-Mougi M, Harrison LH et al. Caretaker recognition of respiratory signs in children: correlation with physical examination signs, x-ray diagnosis and pulse oximetry. Int J Epidemiol. 1993;22(6):1166–1173. https://doi.org/10.1093/ije/22.6.1166.</mixed-citation><mixed-citation xml:lang="en">Gadomski AM, Aref GH, Hassanian F, el Ghandour S, el-Mougi M, Harrison LH et al. Caretaker recognition of respiratory signs in children: correlation with physical examination signs, x-ray diagnosis and pulse oximetry. Int J Epidemiol. 1993;22(6):1166–1173. https://doi.org/10.1093/ije/22.6.1166.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Hay AD, Wilson A, Fahey T, Peters TJ. The duration of acute cough in preschool children: a prospective cohort study. Fam Pract. 2003;20(6):696–705. https://doi.org/10.1093/fampra/cmg613.</mixed-citation><mixed-citation xml:lang="en">Hay AD, Wilson A, Fahey T, Peters TJ. The duration of acute cough in preschool children: a prospective cohort study. Fam Pract. 2003;20(6):696–705. https://doi.org/10.1093/fampra/cmg613.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Hay AD, Fahey T, Peters TJ, Wilson A. Predicting complications from acute cough in pre-school children in primary care: a prospective cohort study. Br J Gen Pract. 2004;54(498):9–14. Available at: https://pubmed.ncbi.nlm.nih.gov/14965400/.</mixed-citation><mixed-citation xml:lang="en">Hay AD, Fahey T, Peters TJ, Wilson A. Predicting complications from acute cough in pre-school children in primary care: a prospective cohort study. Br J Gen Pract. 2004;54(498):9–14. Available at: https://pubmed.ncbi.nlm.nih.gov/14965400/.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Gunn VL, Taha SH, Liebelt EL, Serwint JR. Toxicity of over-the-counter cough and cold medications. Pediatrics. 2001;108(3):E52. https://doi.org/10.1542/peds.108.3.e52.</mixed-citation><mixed-citation xml:lang="en">Gunn VL, Taha SH, Liebelt EL, Serwint JR. Toxicity of over-the-counter cough and cold medications. Pediatrics. 2001;108(3):E52. https://doi.org/10.1542/peds.108.3.e52.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Marseglia GL, Manti S, Chiappini E, Brambilla I, Caffarelli C, Calvani M et al. Acute cough in children and adolescents: A systematic review and a practical algorithm by the Italian Society of Pediatric Allergy and Immunology. Allergol Immunopathol. 2021;49(2):155–169. https://doi.org/10.15586/aei.v49i2.45.</mixed-citation><mixed-citation xml:lang="en">Marseglia GL, Manti S, Chiappini E, Brambilla I, Caffarelli C, Calvani M et al. Acute cough in children and adolescents: A systematic review and a practical algorithm by the Italian Society of Pediatric Allergy and Immunology. Allergol Immunopathol. 2021;49(2):155–169. https://doi.org/10.15586/aei.v49i2.45.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Bergmann M, Haasenritter J, Beidatsch D, Schwarm S, Horner K, Bosner S et al. Coughing children in family practice and primary care: a systematic review of prevalence, aetiology and prognosis. BMC Pediatrics. 2021;21(1):260. https://doi.org/10.1186/s12887-021-02739-4.</mixed-citation><mixed-citation xml:lang="en">Bergmann M, Haasenritter J, Beidatsch D, Schwarm S, Horner K, Bosner S et al. Coughing children in family practice and primary care: a systematic review of prevalence, aetiology and prognosis. BMC Pediatrics. 2021;21(1):260. https://doi.org/10.1186/s12887-021-02739-4.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Shields MD, Bush A, Everard ML, McKenzie S, Primhak R. BTS guidelines: Recommendations for the assessment and management of cough in children. Thorax. 2008;63(Suppl 3):iii1–iii15. https://doi.org/10.1136/thx.2007.077370.</mixed-citation><mixed-citation xml:lang="en">Shields MD, Bush A, Everard ML, McKenzie S, Primhak R. BTS guidelines: Recommendations for the assessment and management of cough in children. Thorax. 2008;63(Suppl 3):iii1–iii15. https://doi.org/10.1136/thx.2007.077370.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Malesker MA, Callahan-Lyon P, Ireland B, Irwin RS. Pharmacologic and Nonpharmacologic Treatment for Acute Cough Associated With the Common Cold CHEST Expert Panel Report. Chest. 2017;152(5):1021–1037. https://doi.org/10.1016/j.chest.2017.08.009.</mixed-citation><mixed-citation xml:lang="en">Malesker MA, Callahan-Lyon P, Ireland B, Irwin RS. Pharmacologic and Nonpharmacologic Treatment for Acute Cough Associated With the Common Cold CHEST Expert Panel Report. Chest. 2017;152(5):1021–1037. https://doi.org/10.1016/j.chest.2017.08.009.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Baxter K, Aikman K, Bloor R, Brayfield A, Buckingham R, Cadart C et al. BNF for Children 2019–2020. BMJ Group; 2019. 1097 р. Available at: https://www.arstapaligs.lv/wp-content/uploads/2021/04/BNF-for-Children-BNFC-2019-2020.pdf.</mixed-citation><mixed-citation xml:lang="en">Baxter K, Aikman K, Bloor R, Brayfield A, Buckingham R, Cadart C et al. BNF for Children 2019–2020. BMJ Group; 2019. 1097 р. Available at: https://www.arstapaligs.lv/wp-content/uploads/2021/04/BNF-for-Children-BNFC-2019-2020.pdf.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Vogelberg C, Schacht FC, Watling CP, Upstone L, Seifert G. Therapeutic principles and unmet needs in the treatment of cough in pediatric patients: review and expert survey. BMC Pediatr. 2023;23(1):34. https://doi.org/10.1186/s12887-022-03814-0.</mixed-citation><mixed-citation xml:lang="en">Vogelberg C, Schacht FC, Watling CP, Upstone L, Seifert G. Therapeutic principles and unmet needs in the treatment of cough in pediatric patients: review and expert survey. BMC Pediatr. 2023;23(1):34. https://doi.org/10.1186/s12887-022-03814-0.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Alsubaie H, Al-Shamrani A, Alharbi AS, Alhaider S. Clinical practice guidelines: Approach to cough in children: The official statement endorsed by the Saudi Pediatric Pulmonology Association (SPPA). Int J Pediatr Adolesc Med. 2015;2(1):38–43. https://doi.org/10.1016/j.ijpam.2015.03.001.</mixed-citation><mixed-citation xml:lang="en">Alsubaie H, Al-Shamrani A, Alharbi AS, Alhaider S. Clinical practice guidelines: Approach to cough in children: The official statement endorsed by the Saudi Pediatric Pulmonology Association (SPPA). Int J Pediatr Adolesc Med. 2015;2(1):38–43. https://doi.org/10.1016/j.ijpam.2015.03.001.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Wagner L, Cramer H, Klose P, Lauche R, Gass F, Dobos G, Langhorst J. Herbal Medicine for Cough: Systematic Review and Meta-Analysis. Forsch Komplementmed. 2015;22(6):359–368. https://doi.org/10.1159/000442111.</mixed-citation><mixed-citation xml:lang="en">Wagner L, Cramer H, Klose P, Lauche R, Gass F, Dobos G, Langhorst J. Herbal Medicine for Cough: Systematic Review and Meta-Analysis. Forsch Komplementmed. 2015;22(6):359–368. https://doi.org/10.1159/000442111.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Бердникова НГ, Цыганко ДВ, Екатеринчев ВА. Использование препаратов растительного происхождения в терапии бронхолегочных заболеваний: доказательная база и практическое применение. Медицинский совет. 2022;16(4):138–145. https://doi.org/10.21518/2079-701X-2022-16-4-138-145.</mixed-citation><mixed-citation xml:lang="en">Berdnikova NG, Tsyganko DV, Ekaterinchev VA. The use of phytopreparations in the treatment of bronchopulmonary diseases: evidence base and practical experience. Meditsinskiy Sovet. 2022;(4):138–145. (In Russ.) https://doi.org/10.21518/2079-701X-2022-16-4-138-145.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Sierocinski E, Holzinger F, Chenot J-F. Ivy leaf (Hedera helix) for acute upper respiratory tract infections: an updated systematic review. Eur J Clin Pharmac. 2021;77(8):1113–1122. https://doi.org/10.1007/s00228-021-03090-4.</mixed-citation><mixed-citation xml:lang="en">Sierocinski E, Holzinger F, Chenot J-F. Ivy leaf (Hedera helix) for acute upper respiratory tract infections: an updated systematic review. Eur J Clin Pharmac. 2021;77(8):1113–1122. https://doi.org/10.1007/s00228-021-03090-4.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Wopker PM, Schwermer M, Sommer S, Langler A, Fetz K, Ostermann T, Zuzak TJ. Complementary and alternative medicine in the treatment of acute bronchitis in children: A systematic review. Complement Ther Med. 2020;49:102217. https://doi.org/10.1016/j.ctim.2019.102217.</mixed-citation><mixed-citation xml:lang="en">Wopker PM, Schwermer M, Sommer S, Langler A, Fetz K, Ostermann T, Zuzak TJ. Complementary and alternative medicine in the treatment of acute bronchitis in children: A systematic review. Complement Ther Med. 2020;49:102217. https://doi.org/10.1016/j.ctim.2019.102217.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Рашитова ЭЛ, Закирова АМ, Мороз ТБ, Шаяпова ДТ, Кадриев АГ, Кадриев АА. Исследование эффектов растительного препарата с комплексным действием в терапии кашля у школьников. Медицинский совет. 2021;(1):100–107. https://doi.org/10.21518/2079-701X-2021-1-100-107.</mixed-citation><mixed-citation xml:lang="en">Rashitova EL, Zakirova AM, Moroz TB, Shayapova DT, Kadriev AG, Kadriev AA. Research of effects of plant preparation with integrated action in cough therapy in school children. Meditsinskiy Sovet. 2021;(1):100–107. (In Russ.) https://doi.org/10.21518/2079-701X-2021-1-100-107.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
