medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/ms2024-433medsovet-8760Research ArticleХРОНИЧЕСКИЕ ЗАБОЛЕВАНИЯ ЛЕГКИХCHRONIC PULMONARY DISEASESПовреждение легких, ассоциированное с курением электронных сигарет (EVALI)Lung damage associated with e-cigarette smoking (EVALI)https://orcid.org/0000-0001-8198-9313БаймакановаГ. Е.BaimakanovaG. E.

Баймаканова Гульсара Есенгельдиевна - д.м.н., заведующая отделом пульмонологии.

111123, Москва, шоссе Энтузиастов, д. 86

Gulsara E. Baimakanova - Dr. Sci. (Med.), Head of the Pulmonology Department of the Loginov Moscow Clinical Scientific Center.

86, Entuziastov Shosse, Moscow, 111123

gulsara.bai@mail.ruhttps://orcid.org/0000-0002-3332-1949ТаракановаИ. Ю.TarakanovaI. Yu.

Тараканова Ирина Юрьевна - младший научный сотрудник отдела пульмонологии.

111123, Москва, шоссе Энтузиастов, д. 86

Irina Yu. Tarakanova - Junior Research Fellow, Pulmonology Department of the Loginov Moscow Clinical Scientific Center.

86, Entuziastov Shosse, Moscow, 111123

i.tarakanova@mknc.ruhttps://orcid.org/0000-0001-8170-1260СамсоноваМ. В.SamsonovaM. V.

Самсонова Мария Викторовна - д.м.н., заведующая лабораторией патологической анатомии и иммунологии, НИИ пульмонологии ФМБА; старший научный сотрудник лаборатории патоморфологии, МКНЦ им. А.С. Логинова.

115682, Москва, Ореховый бульвар, д. 28; 111123, Москва, шоссе Энтузиастов, д. 86

Maria V. Samsonova - Dr. Sci. (Med.), Head of the Laboratory of Pathological Anatomy and Immunology, Research Institute for Pulmonology of the Federal Medical Biological Agency; Senior Researcher, Laboratory of Pathomorphology, Loginov Moscow Clinical Scientific Center.

8, Orekhovy Boulevard, Moscow, 115682; 86, Entuziastov Shosse, Moscow, 111123

samary@mail.ruhttps://orcid.org/0000-0002-2266-1497БелоглазоваИ. П.BeloglazovaI. P.

Белоглазова Ирина Павловна - к.м.н., заведующая терапевтическим отделением №4, ГКБ №52; доцент кафедры общей терапии факультета дополнительного профессионального образования, РНИМУ им. Н.И. Пирогова.

123182, Москва, ул. Пехотная, д. 3; 117997, Москва, ул. Островитянова, д. 1

Irina P. Beloglazova - Cand. Sci. (Med.), Head of Therapeutic Department No. 4, Municipal Clinical Hospital No. 52 of the Department of Healthcare of the City of Moscow; Associate Professor, Department of General Therapy, FDPE, Pirogov Russian National Research Medical University.

3, Pekhotnaya St., Moscow, 123182; 1, Ostrovityanov St., Moscow, 117997

beloglazova.irina@gmail.comhttps://orcid.org/0009-0009-6410-7126КанееваИ. В.KaneevaI. V.

Канеева Ирина Витальевна - врач-терапевт терапевтического отделения №4.

123182, Москва, ул. Пехотная, д. 3

Irina V. Kaneeva - General Practitioner of Therapeutic Department No. 4, Municipal Clinical Hospital No. 52 of the Department of Healthcare of the City of Moscow.

3, Pekhotnaya St., Moscow, 123182

irina.kaneeva@mail.ruhttps://orcid.org/0009-0009-9783-0193ЧерниковаЕ. Н.ChernikovaE. N.

Черникова Екатерина Николаевна - врач-эндоскопист отделения оперативной эндоскопии.

111123, Москва, шоссе Энтузиастов, д. 86

Ekaterina N. Chernikova - Endoscopist of the Operative Endoscopy Department of the Loginov Moscow Clinical Scientific Center.

86, Entuziastov Shosse, Moscow, 111123

e.chernikova@mknc.ruhttps://orcid.org/0000-0002-6369-1801МанченкоО. В.ManchenkoO. V.

Манченко Оксана Владимировна - к.м.н., врач-рентгенолог рентгенологического отделения.

123182, Москва, ул. Пехотная, д. 3

Oksana V. Manchenko - Cand. Sci. (Med.), Radiologist of the Radiology Department, Municipal Clinical Hospital No. 52 of the Department of Healthcare of the City of Moscow.

3, Pekhotnaya St., Moscow, 123182

o-manchenko@ya.ruhttps://orcid.org/0009-0003-7812-0889ЦюкалоД. А.TsiukaloD. A.

Цюкало Дмитрий Андреевич - ординатор кафедры общей терапии факультета дополнительного профессионального образования Института непрерывного образования и профессионального развития.

117997, Москва, ул. Островитянова, д. 1

Dmitrii A. Tsiukalo - Resident, Department of General Internal Medicine of FDPE, Institute of Continuing Education and Professional Development, Pirogov Russian National Research Medical University.

1, Ostrovityanov St., Moscow, 117997

dim4090102@yandex.ruМосковский клинический научный центр имени А.С. ЛогиноваРоссияLoginov Moscow Clinical Scientific CenterRussian FederationМосковский клинический научный центр имени А.С. Логинова; Научно-исследовательский институт пульмонологии Федерального медико-биологического агентстваРоссияLoginov Moscow Clinical Scientific Center; Research Institute for Pulmonology of the Federal Medical Biological AgencyRussian FederationРоссийский национальный исследовательский медицинский университет имени Н.И. Пирогова; Городская клиническая больница №52РоссияPirogov Russian National Research Medical University; Municipal Clinical Hospital No. 52Russian FederationГородская клиническая больница №52РоссияMunicipal Clinical Hospital No. 52Russian FederationРоссийский национальный исследовательский медицинский университет имени Н.И. ПироговаРоссияPirogov Russian National Research Medical UniversityRussian Federation2024111220240203039Copyright © Баймаканова Г.Е., Тараканова И.Ю., Самсонова М.В., Белоглазова И.П., Канеева И.В., Черникова Е.Н., Манченко О.В., Цюкало Д.А., 20242024Баймаканова Г.Е., Тараканова И.Ю., Самсонова М.В., Белоглазова И.П., Канеева И.В., Черникова Е.Н., Манченко О.В., Цюкало Д.А.Baimakanova G.E., Tarakanova I.Y., Samsonova M.V., Beloglazova I.P., Kaneeva I.V., Chernikova E.N., Manchenko O.V., Tsiukalo D.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/8760

В статье описаны клинические случаи повреждения легких, ассоциированного с курением электронных сигарет, — «болезнь вейперов» (англ. EVALI, от E-cigarette and Vaping use-Associated Lung Injury) с кратким обзором литературы. В связи с распространением и популяризацией электронных сигарет поражение легких, ассоциированное с их курением, встречается все чаще. Термин EVALI появился в 2019 г. во время самой масштабной вспышки заболевания в США, тогда же были разработаны критерии верификации диагноза. В обзоре приведены описания разнообразных устройств для вейпинга и курительных жидкостей, представлены возможные механизмы повреждения ткани легких, возникающие в результате курения электронных сигарет, а также травматические воздействия в результате взрыва литиевых батарей вейпов. Наиболее частыми клиническими проявлениями являются респираторные (одышка, кашель, боль в груди, кровохаркание), конституциональные (лихорадка, общая слабость) и гастроэнтерологические (тошнота, рвота, диарея, боль в животе) симптомы. Рентгенологическая и гистологическая картина заболевания неспецифична и разнообразна. Диагностика «болезни вейперов» включает широкий комплекс исследований и является диагнозом исключения. В лечении EVALI нет стандартизированных подходов, но большинству пациентов требуется кислородотерапия, респираторная поддержка и применение системных глюкокортикостероидов. В современной литературе отсутствуют сведения о хроническом поражении легких на фоне курения электронных сигарет. В представленной статье описаны клинические случаи острого повреждения легочной ткани и отдаленных последствий в результате вейпинга. Таким образом, EVALI является новым заболеванием, требующим дальнейшего наблюдения и изучения.

This article describes clinical cases of lung damage associated with e-cigarette smoking, EVALI (from E-cigarette and Vaping use-Associated Lung Injury) with a brief review of the literature. With the proliferation and popularization of electronic cigarettes, lung injury associated with their smoking is becoming more common. The term EVALI emerged in 2019 during the largest outbreak in the United States of America (USA), at which time criteria for verifying the diagnosis were developed. This review provides descriptions of a variety of vaping devices and smoking liquids, presents possible mechanisms of lung tissue damage resulting from smoking e-cigarettes, as well as traumatic effects from exploding lithium vape batteries. The most frequent clinical manifestations are respiratory (dyspnea, cough, chest pain, hemoptysis), constitutional (fever, general weakness) and gastroenterologic (nausea, vomiting, diarrhea, abdominal pain) symptoms. The radiologic and histologic pictures of the disease are nonspecific and varied. The diagnosis of “vape disease” includes a wide range of investigations and is a “diagnosis of exclusion”. There are no standardized approaches in the treatment of EVALI, but most patients require oxygen therapy, respiratory support, and the use of systemic glucocorticosteroids. In the current literature there is no information about chronic lung damage against the background of smoking electronic cigarettes. The presented article describes clinical cases of acute lung tissue damage and long-term consequences as a result of vaping. Thus, EVALI is an emerging disease requiring further surveillance and study.

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The authors declare that there are no conflicts of interest present.