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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/ms2025-080</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-9002</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НЕРВНО-ПСИХИЧЕСКИЕ РАССТРОЙСТВА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NEUROPSYCHIATRIC DISORDERS</subject></subj-group></article-categories><title-group><article-title>Нарушения сна при паническом расстройстве</article-title><trans-title-group xml:lang="en"><trans-title>Sleep disturbance in panic disorder</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2370-4540</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яковлева</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Yakovleva</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Яковлева Елена Вячеславовна - врач-невролог.</p><p>111398, Москва, ул. Плющева, 15а, стр. 2</p></bio><bio xml:lang="en"><p>Elena V. Yakovleva – Neurologist.</p><p>15а, Bldg. 2, Plushchev St., Moscow, 111398</p></bio><email xlink:type="simple">alena_yakovleva_00@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4548-0012</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Корабельникова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Korabelnikova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Корабельникова Елена Александровна - д.м.н., профессор кафедры нервных болезней.</p><p>119991, Москва, ул. Трубецкая, д. 8, стр. 2</p></bio><bio xml:lang="en"><p>Elena A. Korabelnikova - Dr. Sci. (Med.), Professor of the Department of Nervous Diseases.</p><p>8, Bldg. 2, Trubetskaya St., Moscow, 119991</p></bio><email xlink:type="simple">e_korabel@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Клиническая больница «РЖД-Медицина» имени Н.А. Семашко</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Clinical Hospital “Russian Railways-Medicine” named after N.A. Semashko</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Первый Московский государственный медицинский университет имени И.М. Сеченова (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Sechenov First Moscow State Medical University (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>12</day><month>04</month><year>2025</year></pub-date><volume>0</volume><issue>3</issue><fpage>103</fpage><lpage>109</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Яковлева Е.В., Корабельникова Е.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Яковлева Е.В., Корабельникова Е.А.</copyright-holder><copyright-holder xml:lang="en">Yakovleva E.V., Korabelnikova E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/9002">https://www.med-sovet.pro/jour/article/view/9002</self-uri><abstract><sec><title>Введение</title><p>Введение. Паническое расстройство (ПР) и нарушения сна патогенетически тесно связаны, формируя порочный круг взаимного негативного влияния. С одной стороны, ПР, характеризующееся повторными паническими атаками и антиципационной тревогой, провоцирует гипервозбуждение центральной нервной системы, что нарушает засыпание и поддержание сна. С другой – инсомния усугубляет тревожную симптоматику, повышая риск рецидивов ПР. Опубликованные в литературе исследования демонстрируют корреляцию нарушений сна и тревожности, что требует комплексного подхода к терапии.</p></sec><sec><title>Цель</title><p>Цель. Оценить динамику нарушений сна на фоне терапии ПР.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В наше исследование были включены 50 человек: 30 пациентов с ПР и нарушениями сна и 20 здоровых. Для оценки качества сна использовались Питтсбургский опросник индекса качества сна (PSQI) и шкала Шпигеля.</p></sec><sec><title>Результаты</title><p>Результаты. У пациентов с ПР были выявлены значительные нарушения сна, статистически значимо отличающиеся от здоровых участников контрольной группы. Обнаружена значимая корреляция между тяжестью основного расстройства и выраженностью нарушений сна: в подгруппе с тяжелым ПР качество сна пациентов по шкалам достоверно хуже, чем в подгруппе с умеренным ПР. После 8 нед. лечения, включающего медикаментозную терапию ПР и не направленного на коррекцию инсомнии, наблюдалось статистически значимое улучшение качества сна, однако не достигающее значений, характерных для здоровых испытуемых.</p></sec><sec><title>Выводы</title><p>Выводы. Медикаментозное лечение ПР высокоэффективно в отношении сопутствующей коморбидной инсомнии, но необходимо использование дополнительных методов коррекции нарушений сна для достижения лучших результатов терапии. Для оптимизации подходов к лечению, подбора подходящих видов терапевтического воздействия необходимы дальнейшие дополнительные исследования.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Panic disorder (PD) and sleep disorders are closely pathologically linked, forming a vicious circle of mutual negative influence. On the one hand, PD, characterized by repeated panic attacks and anxiety, provokes hyperarousal of the nervous system, which disrupts sleeping and sleep maintenance. On the other hand, insomnia aggravates the worrying symptom, increasing the risk of PD recurrence. Published studies demonstrate a correlation between sleep disturbances and anxiety, necessitating a comprehensive approach to therapy.</p></sec><sec><title>Aim</title><p>Aim. To evaluate the dynamics of sleep disorders during the treatment of PD.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. Our study included 50 participants: 30 with PD and sleep disorders and 20 healthy. The Pittsburgh Sleep Quality Index (PSQI) and the Spiegel Scale were used to assess sleep quality.</p></sec><sec><title>Results</title><p>Results. Testing of patients with PD revealed significant sleep disturbances, statistically significantly different from those of the healthy control group participants. A significant correlation was found between the severity of the primary disorder and the degree of sleep disturbances: in the subgroup with severe PD, sleep quality was significantly worse according to the scales than in the subgroup with moderate PD. After 8 weeks of treatment, including pharmacotherapy for PD and not specifically targeting insomnia, a statistically significant improvement in sleep quality was observed, although it did not reach the levels characteristic of healthy subjects.</p></sec><sec><title>Conclusions</title><p>Conclusions. Pharmacological treatment of PD is highly effective in addressing comorbid insomnia, but additional methods for correcting sleep disturbances are necessary to achieve better therapeutic outcomes. Further research is needed to optimize treatment approaches and select appropriate therapeutic interventions.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>паническое расстройство</kwd><kwd>качество сна</kwd><kwd>нарушения сна</kwd><kwd>инсомния</kwd><kwd>тревожность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>panic disorder</kwd><kwd>sleep quality</kwd><kwd>sleep disorders</kwd><kwd>insomnia</kwd><kwd>anxiety</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kessler RC, Chiu WT, Jin R, Ruscio AM, Shear K, Walters EE. The epidemiology of panic attacks, panic disorder, and agoraphobia in the National Comorbidity Survey Replication. 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