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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/ms2025-140</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-9026</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>РЕПРОДУКТИВНОЕ ЗДОРОВЬЕ И ВРТ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REPRODUCTIVE HEALTH AND ART</subject></subj-group></article-categories><title-group><article-title>Гормональная низкодозированная внутриматочная контрацепция: новые возможности</article-title><trans-title-group xml:lang="en"><trans-title>Low-dose hormonal intrauterine contraception: New options</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3993-7629</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Прилепская</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Prilepskaya</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Прилепская Вера Николаевна, д.м.н., профессор, заведующая научно-поликлиническим отделением</p><p>117997, Москва, ул. Академика Опарина, д. 4</p></bio><bio xml:lang="en"><p>Vera N. Prilepskaya, Dr. Sci. (Med.), Professor, Head of the Scientific and Polyclinic Department</p><p>4, Academician Oparin St., Moscow, 117997</p></bio><email xlink:type="simple">Vprilepskaya@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0574-1230</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мгерян</surname><given-names>A. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Mgeryan</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мгерян Анна Нерсесовна, к.м.н., врач – акушер-гинеколог, научный сотрудник научно-поликлинического отделения</p><p>117997, Москва, ул. Академика Опарина, д. 4</p></bio><bio xml:lang="en"><p>Anna N. Mgeryan, Cand. Sci. (Med.), Obstetrician-Gynecologist, Researcher at the Scientific and Polyclinic Department</p><p>4, Academician Oparin St., Moscow, 117997</p></bio><email xlink:type="simple">docanna@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2977-9065</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Межевитинова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mezhevitinova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Межевитинова Елена Анатольевна, д.м.н., врач – акушер-гинеколог, ведущий научный сотрудник научно-поликлинического отделения</p><p>117997, Москва, ул. Академика Опарина, д. 4</p></bio><bio xml:lang="en"><p>Elena A. Mezhevitinova, Dr. Sci. (Med.), Obstetrician-Gynecologist, Leading Researcher at the Scientific and Outpatient Department</p><p>4, Academician Oparin St., Moscow, 117997</p></bio><email xlink:type="simple">e_mezhevitinova@oparina4.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2835-6685</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Довлетханова</surname><given-names>Э. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Dovletkhanova</surname><given-names>E. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Довлетханова Эльмира Робертовна, к.м.н., врач – акушер-гинеколог, старший научный сотрудник научно-поликлинического отделения</p><p>117997, Москва, ул. Академика Опарина, д. 4</p></bio><bio xml:lang="en"><p>Elmira R. Dovletkhanova, Cand. Sci. (Med.), Obstetrician-Gynecologist, Senior Researcher at the Scientific and Polyclinic Department</p><p>4, Academician Oparin St., Moscow, 117997</p></bio><email xlink:type="simple">eldoc@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Национальный медицинский исследовательский центр акушерства, гинекологии и перинатологии имени академика В.И. Кулакова<country>Россия</country></aff><aff xml:lang="en">Kulakov National Medical Research Center of Obstetrics, Gynecology and Perinatology<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>26</day><month>04</month><year>2025</year></pub-date><volume>0</volume><issue>4</issue><fpage>70</fpage><lpage>75</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Прилепская В.Н., Мгерян A.Н., Межевитинова Е.А., Довлетханова Э.Р., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Прилепская В.Н., Мгерян A.Н., Межевитинова Е.А., Довлетханова Э.Р.</copyright-holder><copyright-holder xml:lang="en">Prilepskaya V.N., Mgeryan A.N., Mezhevitinova E.A., Dovletkhanova E.R.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/9026">https://www.med-sovet.pro/jour/article/view/9026</self-uri><abstract><p>В статье представлен анализ данных литературы о современных возможностях гормональных внутриматочных контрацептивных систем. Внутриматочные системы (ВМС) являются одним из эффективных, безопасных и приемлемых методов контрацепции. Согласно статистике около 1/3 женского населения России, 1/2 – женщины Восточной Азии в качестве контрацепции выбирают ВМС, что по всей вероятности связано с отсутствием возможности и желания постоянного контроля за применением контрацептивного средства (таблетки, пластырь, интравагинальное кольцо). В ряде исследований, проведенных в последние 10 лет, отмечается более чем 3-кратное увеличение частоты применения ВМС у женщин в возрасте 15–24 лет. До недавнего времени гормональные ВМС, как правило, применялись у рожавших женщин. Однако новая ВМС, содержащая 19,5 мг левоноргестрела (ЛНГ), активно применяется более чем в 30 странах мира в качестве высокоэффективного и приемлемого метода контрацепции с низким содержанием левоноргестрела. Было проведено немало исследований, направленных на изучение эффективности, приемлемости и безопасности ВМС. Так, в одном из крупнейших проспективных наблюдательных многоцентровых исследований KYSS проводилась оценка удовлетворенности использованием ЛНГ-ВМС в течение одного года. В исследование было включено 1 114 женщин. Результаты исследования показали удовлетворенность от данного метода контрацепции у 86,1% женщин, желание продолжить применение этого способа контрацепции – 81,4%, а также невысокий процент (16,9%) нежелательных явлений. Следовательно, ЛНГ-ВМС представляет собой эффективный, приемлемый, безопасный метод контрацепции, позволяющий предотвратить наступление нежелательной беременности в том числе и у молодых нерожавших женщин.</p></abstract><trans-abstract xml:lang="en"><p>The article presents an analysis of the literature data on the modern possibilities of hormonal intrauterine contraceptive systems. Intrauterine systems (IUDs) are one of the most effective, safe and acceptable methods of contraception. According to statistics, about 1/3 of the female population of Russia, 1/2 – women of East Asia use IUD as contraception, which is most likely due to the lack of opportunity and desire for constant monitoring of the use of contraceptives (pills, patch, intravaginal ring). In a number of studies conducted in the last 10 years, there has been a more than threefold increase in the frequency of IUD use in women aged 15–24 years. Until recently, hormonal IUDs (Mirena) were usually used in women who gave birth, but the development of a new IUD, Kailin, containing 19.5 mg of levonorgestrel, is actively used in more than 30 countries around the world as a highly effective and acceptable method of contraception with a low content of LNG. Many studies have been conducted to investigate the effectiveness, acceptability and safety of IUD. Thus, in one of the largest prospective observational multicenter KYSS study, satisfaction with the use of IUD LNG was assessed for one year. The study included 1,114 women. The results of the study showed: satisfaction with this method of contraception in 86.1% of women, the desire to continue using Kailina – 81.4%, as well as a low percentage (16.9%) of adverse events. Therefore, IUD-LNG IUD is an effective, acceptable, safe method of contraception that allows to prevent the onset of unwanted pregnancy, including in young unborn women. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>ВМС</kwd><kwd>ЛНГ-ВМС</kwd><kwd>внутриматочная гормональная контрацепция</kwd><kwd>левоноргестрел</kwd><kwd>низкодозированная внутриматочная система</kwd></kwd-group><kwd-group xml:lang="en"><kwd>IUD</kwd><kwd>IUD-LNG</kwd><kwd>intrauterine hormonal contraception</kwd><kwd>levonorgestrel</kwd><kwd>low-dose intrauterine system</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Петров ЮА. 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