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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/ms2025-048</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-9085</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КОМОРБИДНЫЙ ПАЦИЕНТ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>COMORBID PATIENT</subject></subj-group></article-categories><title-group><article-title>Ретробульбарная боль при изолированном сфеноидите</article-title><trans-title-group xml:lang="en"><trans-title>Retrobulbar pain in isolated sphenoiditis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1874-8095</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Арустамян</surname><given-names>И. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Arustamyan</surname><given-names>I. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Арустамян Ирина Григорьевна - к.м.н., научный сотрудник.</p><p>190013, Санкт-Петербург, ул. Бронницкая, д. 9</p></bio><bio xml:lang="en"><p>Irina G. Arustamyan - Cand. Sci. (Med.), Research Associate, Saint Petersburg Research Institute of Ear, Throat, Nose and Speech.</p><p>9, Bronnitskaya St., St Petersburg, 190013</p></bio><email xlink:type="simple">a-irina26@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1124-1937</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карпищенко</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Karpischenko</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Карпищенко Сергей Анатольевич - д.м.н., профессор, заведующий кафедрой оториноларингологии с клиникой.</p><p>197022, Санкт-Петербург, ул. Льва Толстого, д. 6–8</p></bio><bio xml:lang="en"><p>Sergey A. Karpishchenko - Dr. Sci. (Med.), Professor, Head of the Department of Otorhinolaryngology with Clinic; Pavlov First Saint Petersburg State Medical University.</p><p>6–8, Lev Tolstoy St., St Petersburg, 197022</p></bio><email xlink:type="simple">karpischenkos@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2172-7992</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Станчева</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Stancheva</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Станчева Ольга Андреевна - к.м.н., врач-оториноларинголог.</p><p>197022, Санкт-Петербург, ул. Льва Толстого, д. 6–8</p></bio><bio xml:lang="en"><p>Olga A. Stancheva - Cand. Sci. (Med.), Otorhinolaryngologist, Pavlov First Saint Petersburg State Medical University.</p><p>6–8, Lev Tolstoy St., St Petersburg, 197022</p></bio><email xlink:type="simple">olga.stancheva@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-6018-7129</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кучерявенко</surname><given-names>М. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kucheryavenko</surname><given-names>M. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кучерявенко Мария Николаевна - врач-оториноларинголог Консультативно-диагностического центра при поликлинике Научно-исследовательского института детской онкологии, гематологии и трансплантологии имени Р.М. Горбачевой.</p><p>197022, Санкт-Петербург, ул. Льва Толстого, д. 6–8</p></bio><bio xml:lang="en"><p>Mariya N. Kucheryavenko - Otorhinolaryngologist, Consultative and Diagnostic Center at the Polyclinic of the Research Institute for Pediatric Oncology, Hematology and Transplantation named after R.M. Gorbacheva, Pavlov First Saint Petersburg State Medical University.</p><p>6–8, Lev Tolstoy St., St Petersburg, 197022</p></bio><email xlink:type="simple">mary.kucheryavenko@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2719-5031</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нерсесян</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Nersesyan</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Нерсесян Марина Владиславовна - д.м.н., профессор.</p><p>117198, Москва, ул. Миклухо-Маклая, д. 6</p></bio><bio xml:lang="en"><p>Marina V. Nersesyan - Dr. Sci. (Med.), Professor, Peoples’ Friendship University of Russia named after Patrice Lumumba.</p><p>6, Miklukho-Maklai St., Moscow, 117198</p></bio><email xlink:type="simple">nermarina@yahoo.com</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2765-4509</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каплун</surname><given-names>Д. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Kaplun</surname><given-names>D. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Каплун Дмитрий Ильич - к.т.н., доцент, заместитель заведующего кафедрой автоматики и процессов управления по научной работе.</p><p>197022, ул. Профессора Попова, д. 5, лит. Ф</p></bio><bio xml:lang="en"><p>Dmitrii I. Kaplun - Cand. Sci. (Eng.), Associate Professor, Deputy Head of the Department of Automation and Control Processes for Scientific Work, Saint Petersburg Electrotechnical University “LETI” named after V.I. Ulyanov (Lenin).</p><p>5, lit. F, Professor Popov St., St Petersburg, 197022</p></bio><email xlink:type="simple">dikaplun@etu.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5851-6160</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шпаковская</surname><given-names>И. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Shpakouskaya</surname><given-names>I. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шпаковская Ирина Игоревна – инженер.</p><p>197022, ул. Профессора Попова, д. 5, лит. Ф</p></bio><bio xml:lang="en"><p>Iryna I. Shpakouskaya - Engineer, Saint Petersburg Electrotechnical University “LETI” named after V.I. Ulyanov (Lenin).</p><p>5, lit. F, Professor Popov St., St Petersburg, 197022</p></bio><email xlink:type="simple">iishpakovskaia@etu.ru</email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Санкт-Петербургский научно-исследовательский институт уха, горла, носа и речи</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint Petersburg Research Institute of Ear, Throat, Nose and Speech</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Первый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pavlov First Saint Petersburg State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Российский университет дружбы народов имени Патриса Лумумбы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Peoples’ Friendship University of Russia named after Patrice Lumumba</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Санкт-Петербургский государственный электротехнический университет «ЛЭТИ» имени В.И. Ульянова (Ленина)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint Petersburg Electrotechnical University “LETI” named after V.I. Ulyanov (Lenin)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>24</day><month>05</month><year>2025</year></pub-date><volume>0</volume><issue>7</issue><fpage>150</fpage><lpage>155</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Арустамян И.Г., Карпищенко С.А., Станчева О.А., Кучерявенко М.Н., Нерсесян М.В., Каплун Д.И., Шпаковская И.И., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Арустамян И.Г., Карпищенко С.А., Станчева О.А., Кучерявенко М.Н., Нерсесян М.В., Каплун Д.И., Шпаковская И.И.</copyright-holder><copyright-holder xml:lang="en">Arustamyan I.G., Karpischenko S.A., Stancheva O.A., Kucheryavenko M.N., Nersesyan M.V., Kaplun D.I., Shpakouskaya I.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/9085">https://www.med-sovet.pro/jour/article/view/9085</self-uri><abstract><sec><title>Введение</title><p>Введение. Одностороннее затенение клиновидной пазухи по данным компьютерной томографии может быть вызвано различными патологическими состояниями: воспалительным или инфекционным процессом, доброкачественными и злокачественными опухолями, а также интра- и экстракраниальными опухолями. Симптомы изолированного поражения данного синуса разнообразны и неспецифичны. К такому признаку относится ретробульбарная боль, которая не встречается при поражении других околоносовых пазух. Это делает данный симптом диагностически ценным.</p></sec><sec><title>Цель</title><p>Цель. Проанализировать взаимосвязь между наличием ретробульбарных болей у пациентов с изолированным сфеноидитом и характером патологических изменений в синусе.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Было проведено ретроспективное когортное исследование в нескольких медицинских учреждениях среди всех пациентов с односторонним затенением клиновидной пазухи в период с 2017 по 2024 г. Были зафиксированы демографические данные пациентов, симптомы, результаты назальной эндоскопии, компьютерной томографии и интраоперационные находки. Для категориальных признаков полученные данные были проанализированы с помощью статистических методов исследования.</p></sec><sec><title>Результаты</title><p>Результаты. На основе анализа было обнаружено, что ретроорбитальная боль чаще выявлялась у пациентов с грибковым образованием клиновидной пазухи в сочетании с гнойным воспалением или без него (p = 0,01), а также чаще наблюдалась у пожилых пациентов. Кроме того, не было замечено корреляции между диплопией и воспалительной патологией в пазухе.</p></sec><sec><title>Заключение</title><p>Заключение. Таким образом, ретроорбитальная боль является предиктором хронического воспаления пазухи, а именно грибкового шара в синусе, требующего оперативного вмешательства в короткие сроки.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. The opacification of the unilateral sphenoidal sinus (USS) in computed tomography is caused by various diseases, including inflammation and infectious sinusitis, benign and malignant tumors and encephalocles. Symptoms of isolated lesions of this sinus are varied and nonspecific. This symptom includes retrobulbar pain, which does not occur with other paranasal spasms. This makes this symptom diagnostically valuable.</p></sec><sec><title>Aim</title><p>Aim. Тo consider the relationship between the presence of retrobulbar pain in patients with isolated sphenoiditis and the nature of pathological changes in the sinus.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. A retrospective cohort study of multiple institutions was conducted on all patients with USS from 2017 to 2024. The demographics of the patients, symptoms, findings of nasal endoscopy and CT scans were recorded. For categorical features, the obtained data were analyzed using statistical methods.</p></sec><sec><title>Results</title><p>Results. Based on the analysis, it was found that retroorbital pain was more often detected in patients with fungal formation of the sphenoid sinus in the association with or without purulent fundus (p = 0.01), and was also more often observed in client patients. Moreover, no correlation was observed between diplopia and inflammatory pathology.</p></sec><sec><title>Conclusion</title><p>Conclusion. Thus, retroorbital pain is a predictor of sinus chronic inflammation, requiring surgical intervention in short time, pathological changes in the sinus.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>функциональная эндоскопическая синус-хирургия</kwd><kwd>синусит</kwd><kwd>клиновидная пазуха</kwd><kwd>патологические изменения в синусе</kwd><kwd>ретроорбитальная боль</kwd></kwd-group><kwd-group xml:lang="en"><kwd>functional endoscopic sinus surgery (FESS)</kwd><kwd>sinusitis</kwd><kwd>sphenoid sinus</kwd><kwd>retroorbital pain</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследование выполнено за счет гранта Российского научного фонда №23-25-00305, https://rscf.ru/project/23-25-00305.</funding-statement><funding-statement xml:lang="en">The study was supported by the Russian Science Foundation grant No. 23-25-00305, https://rscf.ru/project/23-25-00305.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Brazis PW, Lee AG, Stewart M, Capobianco D. 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