medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/ms2025-033medsovet-9126Research ArticleКОМОРБИДНЫЙ ПАЦИЕНТCOMORBID PATIENTОсобенности эхокардиографических изменений у пациентов с высоким кардиоваскулярным риском и углеводными нарушениями после поражения легких при COVID-19Changes in echocardiography in patients with high cardiovascular risk and hyperglycemia in the post-COVID periodhttps://orcid.org/0000-0003-0466-7059РедькинаИ. Н.RedkinaI. N.

Редькина Ирина Николаевна, эндокринолог, аспирант кафедры терапии с курсом эндокринологии; врач-эндокринолог

625023, Россия, Тюмень, ул. Одесская, д. 54

625026, Россия, Тюмень, ул. Мельникайте, д. 111 

Irina N. Redkina, Endocrinologist, Postgraduate Student of the Department of Therapy with a Course in Endocrinology; Endocrinologist 

54, Odesskaya St., Tyumen, 625023, Russia

111, Melnikaite St., Tyumen, 625026, Russia

irina.redk@mail.ruhttps://orcid.org/0000-0001-9253-8075СуплотоваЛ. А.SuplotovaL. A.

Суплотова Людмила Александровна, д.м.н., профессор, заведующая курсом эндокринологии кафедры терапии

625023, Россия, Тюмень, ул. Одесская, д. 54 

Lyudmila A. Suplotova, Dr. Sci. (Med.), Professor, Head of the Course in Endocrinology of the Department of Therapy

54, Odesskaya St., Tyumen, 625023, Russia

suplotovala@mail.ruhttps://orcid.org/0000-0002-2686-3715БессоноваМ. И.BessonovaM. I.

Бессонова Марина Игоревна, к.м.н., заслуженный врач РФ, директор

625026, Россия, Тюмень, ул. Мельникайте, д. 111

Marina I. Bessonova, Cand. Sci. (Med.), Honored Doctor of the Russian Federation, Director

111, Melnikaite St., Tyumen, 625026, Russia

priemnaya@infarkta.nethttps://orcid.org/0000-0003-1436-8853ЯрославскаяЕ. И.YaroslavskayaE. I.

Ярославская Елена Ильинична, д.м.н., профессор, заведующая лабораторией инструментальной диагностики, учебно-методического отдела, врач ультразвуковой диагностики

625026, Россия, Тюмень, ул. Мельникайте, д. 111

Elena I. Yaroslavskaya, Dr. Sci. (Med.), Professor, Head of the Laboratory of Instrumental Diagnostics, Educational and Methodological Department, Ultrasound Diagnostics Physician

111, Melnikaite St., Tyumen, 625026, Russia

yaroslavskayae@gmail.comhttps://orcid.org/0000-0002-2134-4107АвдееваК. С.AvdeevaK. S.

Авдеева Ксения Сергеевна, к.м.н., заведующая лабораторией реабилитации и профилактики сердечно-сосудистых заболеваний

625026, Россия, Тюмень, ул. Мельникайте, д. 111

Ksenia S. Avdeeva, Dr. Sci. (Med.), Head of the Laboratory of Rehabilitation and Prevention of Cardiovascular Diseases

111, Melnikaite St., Tyumen, 625026, Russia

avdeevaks@infarkta.nethttps://orcid.org/0000-0001-6251-4179ПетелинаТ. И.PetelinaT. I.

Петелина Татьяна Ивановна, д.м.н., профессор кафедры учебно-методической работы, заведующая лабораторией клинической диагностики и молекулярно-генетических исследований,  заместитель директора по научной работе

625026, Россия, Тюмень, ул. Мельникайте, д. 111

Tatyana I. Petelina, Dr. Sci. (Med.), Professor of the Department of Educational and Methodological Work, Head of the Laboratory of Clinical Diagnostics and Molecular Genetic Research, Deputy Director for Research

111, Melnikaite St., Tyumen, 625026, Russia

petelina@infarkta.nethttps://orcid.org/0000-0002-5061-9210ГультяеваЕ. П.GultyaevaE. P.

Гультяева Елена Павловна, к.м.н., врач-кардиолог, заведующая консультативным отделением, старший научный сотрудник отделения артериальной гипертонии и коронарной недостаточности

625026, Россия, Тюмень, ул. Мельникайте, д. 111

Elena P. Gultyaeva, Cand. Sci. (Med.), Cardiologist, Head of the Consultative Department, Senior Researcher of the Department of Arterial Hypertension and Coronary Insufficiency

111, Melnikaite St., Tyumen, 625026, Russia

gultyaeva@infarkta.nethttps://orcid.org/0000-0002-1655-3705РоманенкоД. А.RomanenkoD. A.

Романенко Дмитрий Андреевич, ординатор по специальности «кардиология», лаборант-исследователь

625026, Россия, Тюмень, ул. Мельникайте, д. 111

Dmitriy A. Romanenko, Resident in the Specialty “Cardiology”, Research Assistant

111, Melnikaite St., Tyumen, 625026, Russia

dmitrijromanenko99@gmail.comТюменский государственный медицинский университет; Тюменский кардиологический научный центр – филиал Томского национального исследовательского медицинского центраРоссияTyumen State Medical University; Tyumen Cardiology Research Center – Branch of the Tomsk National Research Medical CenterRussian FederationТюменский государственный медицинский университетРоссияTyumen State Medical UniversityRussian FederationТюменский кардиологический научный центр – филиал Томского национального исследовательского медицинского центраРоссияTyumen Cardiology Research Center – Branch of the Tomsk National Research Medical CenterRussian Federation20252405202506222229Copyright © Редькина И.Н., Суплотова Л.А., Бессонова М.И., Ярославская Е.И., Авдеева К.С., Петелина Т.И., Гультяева Е.П., Романенко Д.А., 20252025Редькина И.Н., Суплотова Л.А., Бессонова М.И., Ярославская Е.И., Авдеева К.С., Петелина Т.И., Гультяева Е.П., Романенко Д.А.Redkina I.N., Suplotova L.A., Bessonova M.I., Yaroslavskaya E.I., Avdeeva K.S., Petelina T.I., Gultyaeva E.P., Romanenko D.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/9126

Введение. Вирус SARS-CoV-2 оказывает выраженное негативное влияние на кардиомиоциты как при остром заболевании, так и в постковидном периоде. Пациенты с высоким кардиоваскулярным риском и углеводными нарушениями, такими как преддиабет или сахарный диабет 2-го типа, особенно подвержены осложнениям после острого COVID-19. Ограниченность научных данных о последствиях SARS-CoV-2 у пациентов высокого кардиоваскулярного риска с углеводными нарушениями обуславливает актуальность настоящего исследования.Цель. Изучить особенности изменений миокарда по данным ЭхоКГ и ЭКГ у пациентов высокого кардиоваскулярного риска с нарушениями углеводного обмена в постковидном периоде.Материалы и методы. В исследование включены 206 пациентов с высоким кардиоваскулярным риском, перенесшие поражение легких при COVID-19 в 2020–2021 гг. и наблюдавшиеся на базе ТКНЦ, из них 62 пациента имели нарушения углеводного обмена (НУО). У всех пациентов проведен подробный сбор анамнеза, оценены антропометрические данные, артериальное давление, частота сердечных сокращений, выполнено инструментальное обследование: ЭКГ и ЭхоКГ.Результаты. Пациенты с высоким кардиоваскулярным риском и НУО на исходной точке и через 12 мес. наблюдения имели бо̀льшие значения передне-заднего размера левого предсердия (ЛП), конечно-диастолического объема (КДО) ЛП и конечносистолического объема (КСО) ЛП. При динамическом наблюдении пациентов с НУО через 3 и 12 мес. после перенесенного поражения легких при COVID-19 значимо увеличились абсолютные и индексированные значения КСО ЛП и КДО ЛП. Уровень гликированного гемоглобина через 12 мес. после COVID-19 имел заметную корреляционную связь с индексом КДО ЛП, индексом КСО ЛП и индексом массы миокарда левого желудочка (ЛЖ). Показатели ЭКГ в конечной точке не отличались.Заключение. У пациентов с НУО, перенесших поражение легких при СОVID-19, наиболее значимые связи показали индексированные систолический и диастолический объемы ЛП, а также индекс массы миокарда ЛЖ.

Introduction. The SARS-CoV-2 virus damages cardiomyocytes both in acute disease and in the post-COVID period. Patients with high cardiovascular risk and hyperglycemia often have complications after COVID-19. The study of the consequences of SARS- CoV-2 in patients with high cardiovascular risk and hyperglycemia is important today.Aim. To study myocardial changes according to echocardiography and electrocardiography data in patients with high cardiovascular risk with hyperglycemia in the post-COVID period.Materials and methods. The study included 206 patients with high cardiovascular risk who had COVID-19 pneumonia in 2020– 2021 and were observed at the Tyumen Cardiology Research Center. Of which 62 patients with hyperglycemia – prediabetes and diabetes mellitus. All patients had anamnesis, anthropometric data, blood pressure, heart rate were measured, ECG and EchoCG were performed.Results. Patients with high cardiovascular risk and hyperglycemia had higher values of left atrial (LA) size, end-diastolic volume and end-systolic volume of the LA after 3 and 12 months of observation. After 3 and 12 months of post-COVID dynamic observation, the LA volume index increased in patients with hyperglycemia. The level of Hb1AС in 12 months after COVID-19 had a noticeable correlation with the LA systolic and diastolic volume indices and left ventricle (LV) myocardial mass index. ECG parameters did not have difference between groups after 12 months of observation.Conclusion. In patients with hyperglycemia, after COVID-19, the most significant were the LA systolic and diastolic volumes indices, as well as the LV myocardial mass index.

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The authors declare that there are no conflicts of interest present.