<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/ms2025-057</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-9127</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КОМОРБИДНЫЙ ПАЦИЕНТ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>COMORBID PATIENT</subject></subj-group></article-categories><title-group><article-title>Сердечно-сосудистый риск у молодых мужчин в зависимости от характера распределения жировой ткани</article-title><trans-title-group xml:lang="en"><trans-title>Cardiovascular risk assessment and its association with body fat distribution pattern in young men</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1530-3106</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Веретюк</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Veretyuk</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Веретюк Варвара Васильевна, ассистент кафедры неотложной терапии с эндокринологией и профпатологией </p><p>630091, Россия, Новосибирск, Красный проспект, д. 52 </p></bio><bio xml:lang="en"><p>Varvara V. Veretyuk, Assistant of the Department of Emergency Therapy with Endocrinology and Occupational Pathology</p><p>52, Krasny Ave., Novosibirsk, 630091, Russia</p></bio><email xlink:type="simple">varvara@veretyuk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0207-7063</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Цыганкова</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tsygankova</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Цыганкова Оксана Васильевна, д.м.н., доцент, профессор кафедры неотложной терапии с эндокринологией и профпатологией; старший научный сотрудник лаборатории клинических биохимических и гормональных исследований терапевтических заболеваний</p><p>630091, Россия, Новосибирск, Красный проспект, д. 52 </p><p>630089, Россия, Новосибирск, ул. Б. Богаткова, д. 175/1 </p></bio><bio xml:lang="en"><p>Oksana V. Tsygankova, Dr. Sci. (Med.), Professor of the Department of Emergency Therapy with Endocrinology and Occupational Pathology; Senior Researcher of the Laboratory of Clinical Biochemical and Hormonal Research of Therapeutic Diseases, </p><p>52, Krasny Ave., Novosibirsk, 630091, Russia</p><p>175/1, B. Bogatkov St., Novosibirsk, 630089, Russia</p></bio><email xlink:type="simple">oksana_c.nsk@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6584-2060</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тимощенко</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Timoshchenko</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тимощенко Ольга Владимировна, к.м.н., научный сотрудник сектора аналитико-методологических проблем терапевтических заболеваний лаборатории  этиопатогенеза и клиники внутренних заболеваний</p><p>630089, Россия, Новосибирск, ул. Б. Богаткова, д. 175/1 </p></bio><bio xml:lang="en"><p>Olga V. Timoshchenko, Cand. Sci. (Med.), Researcher of the Sector of Analytical and Methodological Problems of Therapeutic Diseases, Laboratory of Etiopathogenesis and Clinic of Internal Diseases</p><p>175/1, B. Bogatkov St., Novosibirsk, 630089, Russia</p></bio><email xlink:type="simple">lentis@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Новосибирский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State&#13;
Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Новосибирский государственный медицинский университет;&#13;
Научно-исследовательский институт терапии и профилактической медицины Федерального исследовательского центра «Институт цитологии и генетики Сибирского отделения Российской академии наук»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State Medical University;&#13;
Research Institute of Internal and Preventive Medicine – Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Научно-исследовательский институт терапии и профилактической медицины Федерального исследовательского центра «Институт цитологии и генетики Сибирского отделения Российской академии наук»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute of Internal and Preventive Medicine – Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>24</day><month>05</month><year>2025</year></pub-date><volume>0</volume><issue>6</issue><fpage>230</fpage><lpage>240</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Веретюк В.В., Цыганкова О.В., Тимощенко О.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Веретюк В.В., Цыганкова О.В., Тимощенко О.В.</copyright-holder><copyright-holder xml:lang="en">Veretyuk V.V., Tsygankova O.V., Timoshchenko O.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/9127">https://www.med-sovet.pro/jour/article/view/9127</self-uri><abstract><p>Введение. Ожирение является одним из ключевых факторов, влияющих на сердечно-сосудистый риск (ССР) у молодых мужчин.Цель. Оценить ССР у молодых мужчин в зависимости от наличия или отсутствия абдоминального ожирения (АО) и типа распределения жировой ткани (ЖТ).Материалы и методы. В одномоментное клиническое исследование включены 150 мужчин 20–45 лет, средний возраст 36 [32; 41] лет. Участники набирались в три группы по 50 человек на основе антропометрии и биоимпедансного анализа (БИА) состава тела: 1-я группа – без АО, 2-я группа – с АО и преимущественно подкожным типом распределения ЖТ, 3-я группа – с АО и преимущественно висцеральным типом распределения ЖТ. Для оценки доли ЖТ и ее распределения использовались антропометрия, калиперометрия, БИА, ультразвуковое исследование. Для оценки ССР использовались шкалы SCORE2, Framingham 2008, PREVENT, QRISK3, Framingham-30, Mayo Clinic Heart Disease Risk Calculator.Результаты. У мужчин без АО по всем рассчитанным шкалам показатель ССР был статистически значимо ниже, чем в группе мужчин с АО и преимущественно висцеральным типом жироотложения. При корреляционном анализе количество баллов по шкалам Framingham 2008, QRISK3, Framingham-30, Mayo Clinic Heart Disease Risk Calculator имело положительные связи со всеми изучаемыми параметрами, отражающими состав тела (rs = 0,275–0,678; p &lt; 0,001), и отрицательную связь со скоростью базального метаболизма (rs = (-0,777) – (-0,285); p &lt; 0,001).Выводы. У молодых мужчин без АО отмечается более низкий ССР в сравнении с мужчинами с АО и висцеральным типом жироотложения. Мужчины с АО имеют сравнимый ССР при преимущественно подкожном или висцеральном типах распределения ЖТ, за исключением относительного риска QRISK3 и оценки по шкале Framingham-30. Величина ССР положительно коррелирует с антропометрическими и ультразвуковыми показателями, отражающими количество висцеральной ЖТ.</p></abstract><trans-abstract xml:lang="en"><p>Introduction. Obesity is one of the key factors affecting cardiovascular risk (CVR) in young men.Aim. To assess CVR in young men depending on the presence or absence of abdominal obesity (AO) and the type of adipose tissue (AТ) distribution.Materials and methods. The cross-sectional clinical study included 150 men aged 20–45 years, average age 36 [32; 41] years. Participants were recruited into three groups of 50 men each, based on anthropometry and bioimpedance analysis (BIA) of body composition: Group 1 – without AO, Group 2 – with AO and predominantly subcutaneous type of AT distribution, Group 3 – with AO and predominantly visceral type of AT distribution. Anthropometric measurements, caliperometry, BIA, and ultrasound were used to assess body fat mass and AT distribution. Risk scores SCORE2, Framingham 2008, PREVENT, QRISK3, Framingham-30, and Mayo Clinic Heart Disease Risk Calculator were used to assess the CVR.Results. In men without AO, the CVR was statistically significantly lower for all the calculated scores than in the group of men with AO and predominantly visceral fat deposition. In a correlation analysis, the number of points of CVR scores Framingham 2008, QRISK3, Framingham-30, Mayo Clinic Heart Disease Risk Calculator had positive connections with all the studied parameters of body composition (rs = 0.275–0.678; p &lt; 0.001) and a negative relationship with the basal metabolic rate (rs = (-0.777) – (-0.285); p &lt; 0.001).Conclusions. Young men without AO have a lower CVR compared to men with AO and visceral fat distribution. Men with AO with predominantly subcutaneous or visceral types of AT distribution have comparable CVR, with the exception of the QRISK3 relative risk assessment and the Framingham-30 score. The CVR value positively correlates with anthropometric and ultrasound parameters reflecting the amount of visceral AT.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ожирение</kwd><kwd>калиперометрия</kwd><kwd>биоимпедансный анализ</kwd><kwd>висцеральное ожирение</kwd><kwd>шкалы оценки сердечно-сосудистого риска</kwd></kwd-group><kwd-group xml:lang="en"><kwd>obesity</kwd><kwd>visceral obesity</kwd><kwd>caliperometry</kwd><kwd>bioelectrical impedance analysis</kwd><kwd>cardiovascular risk scores</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа выполнена частично по Государственному заданию в рамках бюджетной темы № FWNR-2024-0004.</funding-statement><funding-statement xml:lang="en">The work was partially completed under the State assignment within the framework of budget topic No. FWNR-2024-0004.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">GBD 2021 Risk Factors Collaborators. Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet. 2024;403(10440):2162–2203. https://doi.org/10.1016/S0140-6736(24)00933-4.</mixed-citation><mixed-citation xml:lang="en">GBD 2021 Risk Factors Collaborators. Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet. 2024;403(10440):2162–2203. https://doi.org/10.1016/S0140-6736(24)00933-4.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Koskinas KC, Van Craenenbroeck EM, Antoniades C, Blüher M, Gorter TM, Hanssen H et al. Obesity and cardiovascular disease: an ESC clinical consensus statement. Eur Heart J. 2024;45(38):4063–4098. https://doi.org/10.1093/eurheartj/ehae508.</mixed-citation><mixed-citation xml:lang="en">Koskinas KC, Van Craenenbroeck EM, Antoniades C, Blüher M, Gorter TM, Hanssen H et al. Obesity and cardiovascular disease: an ESC clinical consensus statement. Eur Heart J. 2024;45(38):4063–4098. https://doi.org/10.1093/eurheartj/ehae508.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Powell-Wiley TM, Poirier P, Burke LE, Després JP, Gordon-Larsen P, Lavie CJ et al. Obesity and Cardiovascular Disease: A Scientific Statement From the American Heart Association. Circulation. 2021;143(21):e984–e1010. https://doi.org/10.1161/CIR.0000000000000973.</mixed-citation><mixed-citation xml:lang="en">Powell-Wiley TM, Poirier P, Burke LE, Després JP, Gordon-Larsen P, Lavie CJ et al. Obesity and Cardiovascular Disease: A Scientific Statement From the American Heart Association. Circulation. 2021;143(21):e984–e1010. https://doi.org/10.1161/CIR.0000000000000973.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Visseren FLJ, Mach F, Smulders YM, Carballo D, Koskinas KC, Bäck M et al. 2021 ESC Guidelines on cardiovascular disease prevention in clinical practice. Eur Heart J. 2021;42(34):3227–3337. https://doi.org/10.1093/eurheartj/ehab484.</mixed-citation><mixed-citation xml:lang="en">Visseren FLJ, Mach F, Smulders YM, Carballo D, Koskinas KC, Bäck M et al. 2021 ESC Guidelines on cardiovascular disease prevention in clinical practice. Eur Heart J. 2021;42(34):3227–3337. https://doi.org/10.1093/eurheartj/ehab484.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Бойцов СА, Погосова НВ, Аншелес АА, Бадтиева ВА, Балахонова ТВ, Барбараш ОЛ и др. Кардиоваскулярная профилактика 2022. Российские национальные рекомендации. Российский кардиологический журнал. 2023;28(5):5452. https://doi.org/10.15829/1560-4071-2023-5452.</mixed-citation><mixed-citation xml:lang="en">Boytsov SA, Pogosova NV, Ansheles AA, Badtieva VA, Balakhonova TV, Barbarash OL et al. Cardiovascular prevention 2022. Russian national guidelines. Russian Journal of Cardiology. 2023;28(5):5452. (In Russ.) https://doi.org/10.15829/1560-4071-2023-5452.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Preda A, Carbone F, Tirandi A, Montecucco F, Liberale L. Obesity phenotypes and cardiovascular risk: From pathophysiology to clinical management. Rev Endocr Metab Disord. 2023;24(5):901–919. https://doi.org/10.1007/s11154-023-09813-5.</mixed-citation><mixed-citation xml:lang="en">Preda A, Carbone F, Tirandi A, Montecucco F, Liberale L. Obesity phenotypes and cardiovascular risk: From pathophysiology to clinical management. Rev Endocr Metab Disord. 2023;24(5):901–919. https://doi.org/10.1007/s11154-023-09813-5.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Mohammadian Khonsari N, Khashayar P, Shahrestanaki E, Kelishadi R, Mohammadpoor Nami S, Heidari-Beni M et al. Normal Weight Obesity and</mixed-citation><mixed-citation xml:lang="en">Mohammadian Khonsari N, Khashayar P, Shahrestanaki E, Kelishadi R, Mohammadpoor Nami S, Heidari-Beni M et al. Normal Weight Obesity and</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Cardiometabolic Risk Factors: A Systematic Review and Meta-Analysis. Front Endocrinol. 2022;13:857930. https://doi.org/10.3389/fendo.2022.857930.</mixed-citation><mixed-citation xml:lang="en">Cardiometabolic Risk Factors: A Systematic Review and Meta-Analysis. Front Endocrinol. 2022;13:857930. https://doi.org/10.3389/fendo.2022.857930.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Jacobs DR Jr, Woo JG, Sinaiko AR, Daniels SR, Ikonen J, Juonala M et al. Childhood Cardiovascular Risk Factors and Adult Cardiovascular Events. N Engl J Med. 2022;386(20):1877–1888. https://doi.org/10.1056/NEJMoa2109191.</mixed-citation><mixed-citation xml:lang="en">Jacobs DR Jr, Woo JG, Sinaiko AR, Daniels SR, Ikonen J, Juonala M et al. Childhood Cardiovascular Risk Factors and Adult Cardiovascular Events. N Engl J Med. 2022;386(20):1877–1888. https://doi.org/10.1056/NEJMoa2109191.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Веретюк ВВ, Цыганкова ОВ, Аметов АС. Оценка сердечно-сосудистого риска у молодых мужчин. Доктор.Ру. 2023;22(4):7–17. https://doi.org/10.31550/1727-2378-2023-22-4-7-17.</mixed-citation><mixed-citation xml:lang="en">Veretyuk VV, Tsygankova OV, Ametov AS. Evaluation of a Cardiovascular Risk in Young Men. Doctor.Ru. 2023;22(4):7–17. (In Russ.) https://doi.org/10.31550/1727-2378-2023-22-4-7-17.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Veretyuk VV, Tsygankova OV, Ametov AS. Evaluation of a Cardiovascular Risk in Young Men. Doctor.Ru. 2023;22(4):7–17. (In Russ.) https://doi.org/10.31550/1727-2378-2023-22-4-7-17.</mixed-citation><mixed-citation xml:lang="en">Human energy requirements: Report of a Joint FAO/WHO/UNU Expert Consultation, Rome 17–24 October 2001. Rome: United Nations University, World Health Organization, Food and Agriculture Organization of the United Nations, 2004. Available at: https://openknowledge.fao.org/server/api/core/bitstreams/65875dc7-f8c5-4a70-b0e1-f429793860ae/content.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Human energy requirements: Report of a Joint FAO/WHO/UNU Expert Consultation, Rome 17–24 October 2001. Rome: United Nations University, World Health Organization, Food and Agriculture Organization of the United Nations, 2004. Available at: https://openknowledge.fao.org/server/api/core/bitstreams/65875dc7-f8c5-4a70-b0e1-f429793860ae/content.</mixed-citation><mixed-citation xml:lang="en">Kasper AM, Langan-Evans C, Hudson JF, Brownlee TE, Harper LD, Naughton RJ et al. Come Back Skinfolds, All Is Forgiven: A Narrative Review of the Efficacy of Common Body Composition Methods in Applied Sports Practice. Nutrients. 2021;13(4):1075. https://doi.org/10.3390/nu13041075.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Kasper AM, Langan-Evans C, Hudson JF, Brownlee TE, Harper LD, Naughton RJ et al. Come Back Skinfolds, All Is Forgiven: A Narrative Review of the Efficacy of Common Body Composition Methods in Applied Sports Practice. Nutrients. 2021;13(4):1075. https://doi.org/10.3390/nu13041075.</mixed-citation><mixed-citation xml:lang="en">Kawamoto R, Oka Y, Tomita H, Kodama A, Ootsuka N. Association between abdominal wall fat index on ultrasonography and carotid atherosclerosis in non-obese men. J Atheroscler Thromb. 2005;12(2):85–91. https://doi.org/10.5551/jat.12.85.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Kawamoto R, Oka Y, Tomita H, Kodama A, Ootsuka N. Association between abdominal wall fat index on ultrasonography and carotid atherosclerosis in non-obese men. J Atheroscler Thromb. 2005;12(2):85–91. https://doi.org/10.5551/jat.12.85.</mixed-citation><mixed-citation xml:lang="en">Pimanov SI, Bondarenko VM, Makarenko EV. Choosing the Optimal Ultrasound Method for the Measurement of the Amount of Visceral Adipose Tissue. Health and Ecology Issues. 2019;(4):105–113. (In Russ.) https://doi.org/10.51523/2708-6011.2019-16-4-21.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Пиманов СИ, Бондаренко ВМ, Макаренко ЕВ. Выбор оптимальной ультразвуковой методики измерения количества висцеральной жировой ткани. Проблемы здоровья и экологии. 2019;(4):105–113. https://doi.org/10.51523/2708-6011.2019-16-4-21.</mixed-citation><mixed-citation xml:lang="en">Kuznetsova TYu, Chumakova GA, Druzhilov MA, Veselovskaya NG. Clinical application of quantitative echocardiographic assessment of epicardial fat tissue in obesity. Russian Journal of Cardiology. 2017;(4):81–87. (In Russ.) https://doi.org/10.15829/1560-4071-2017-4-81-87.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Кузнецова ТЮ, Чумакова ГА, Дружилов МА, Веселовская НГ. Роль количественной эхокардиографической оценки эпикардиальной жировой ткани у пациентов с ожирением в клинической практике. Российский кардиологический журнал. 2017;(4):81–87. https://doi.org/10.15829/1560-4071-2017-4-81-87.</mixed-citation><mixed-citation xml:lang="en">Drapkina OM, Angarsky RK, Rogozhkina EA, Maksimova OA, Ivanova AA, Zyatenkova EV, Dzhioeva ON. Ultrasound-assisted assessment of visceral and subcutaneous adipose tissue thickness. Methodological guidelines. Cardiovascular Therapy and Prevention (Russian Federation). 2023;22(3):3552. (In Russ.) https://doi.org/10.15829/1728-8800-2023-3552.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Драпкина ОМ, Ангарский РК, Рогожкина ЕА, Максимова ОА, Иванова АА, Зятенкова ЕВ, Джиоева ОН. Российское общество профилактики неинфекционных заболеваний. Ультразвук-ассистированная оценка толщины висцеральной и подкожной жировой ткани. Методические рекомендации. Кардиоваскулярная терапия и профилактика. 2023;22(3):3552. https://doi.org/10.15829/1728-8800-2023-3552.</mixed-citation><mixed-citation xml:lang="en">Ryabikov AN, Guliev ZZ, Malyutina SK, Ragino YuI. Novel ultrasonic marker of the thickness of premesenterial fat: the relationship with metabolic indicators and risk factors of cardiovascular diseases. Ateroskleroz. 2013;9(2):11–19. (In Russ.) Available at: https://ateroskleroz.elpub.ru/jour/article/view/672.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Рябиков АН, Гулиев ЗЗ, Малютина СК, Рагино ЮИ. Новый ультразвуковой маркер – толщина премезентериального жира: связь с метаболическими индикаторами и факторами риска сердечно-сосудистых заболеваний. Атеросклероз. 2013;9(2):11–19. Режим доступа: https://ateroskleroz.elpub.ru/jour/article/view/672.</mixed-citation><mixed-citation xml:lang="en">Anderson TS, Wilson LM, Sussman JB. Atherosclerotic Cardiovascular Disease Risk Estimates Using the Predicting Risk of Cardiovascular Disease Events Equations. JAMA Intern Med. 2024;184(8):963–970. https://doi.org/10.1001/jamainternmed.2024.1302.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Anderson TS, Wilson LM, Sussman JB. Atherosclerotic Cardiovascular Disease Risk Estimates Using the Predicting Risk of Cardiovascular Disease Events Equations. JAMA Intern Med. 2024;184(8):963–970. https://doi.org/10.1001/jamainternmed.2024.1302.</mixed-citation><mixed-citation xml:lang="en">Suzuki R, Watanabe S, Hirai Y, Akiyama K, Nishide T, Matsushima Y et al. Abdominal wall fat index, estimated by ultrasonography, for assessment of the ratio of visceral fat to subcutaneous fat in the abdomen. Am J Med. 1993;95(3):309–314. https://doi.org/10.1016/0002-9343(93)90284-v.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Suzuki R, Watanabe S, Hirai Y, Akiyama K, Nishide T, Matsushima Y et al. Abdominal wall fat index, estimated by ultrasonography, for assessment of the ratio of visceral fat to subcutaneous fat in the abdomen. Am J Med. 1993;95(3):309–314. https://doi.org/10.1016/0002-9343(93)90284-v.</mixed-citation><mixed-citation xml:lang="en">Tadokoro N, Murano S, Nishide T, Suzuki R, Watanabe S, Murayama H et al. Preperitoneal fat thickness determined by ultrasonography is correlated with coronary stenosis and lipid disorders in non-obese male subjects. Int J Obes Relat Metab Disord. 2000;24(4):502–507. https://doi.org/10.1038/sj.ijo.0801187.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Tadokoro N, Murano S, Nishide T, Suzuki R, Watanabe S, Murayama H et al. Preperitoneal fat thickness determined by ultrasonography is correlated with coronary stenosis and lipid disorders in non-obese male subjects. Int J Obes Relat Metab Disord. 2000;24(4):502–507. https://doi.org/10.1038/sj.ijo.0801187.</mixed-citation><mixed-citation xml:lang="en">Cigankova OV, Nikolaev KY, Fedorova EL, Bondareva ZG. Sex hormones methabolism in men through the prism of vardiovascular risk. The Journal of Atherosclerosis and Dyslipidemias. 2014;(1):17–24. (In Russ.) Available at: https://jad.noatero.ru/index.php/jad/article/view/92/91.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Цыганкова ОВ, Николаев КЮ, Федорова ЕЛ, Бондарева ЗГ. Обмен половых гормонов в организме мужчины через призму кардиоваскулярного риска. Атеросклероз и дислипидемии. 2014;(1):17–24. Режим доступа: https://jad.noatero.ru/index.php/jad/article/view/92/91.</mixed-citation><mixed-citation xml:lang="en">Bazzocchi A, Ponti F, Diano D, Moio A, Albisinni U, Pasquali R, Battista G. Abdominal adiposity by ultrasonography: a “pocket” database for reference standard in Italian people. Prim Care Diabetes. 2014;8(4):358–364. https://doi.org/10.1016/j.pcd.2014.02.003.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Bazzocchi A, Ponti F, Diano D, Moio A, Albisinni U, Pasquali R, Battista G. Abdominal adiposity by ultrasonography: a “pocket” database for reference standard in Italian people. Prim Care Diabetes. 2014;8(4):358–364. https://doi.org/10.1016/j.pcd.2014.02.003.</mixed-citation><mixed-citation xml:lang="en">Kong M, Xu M, Zhou Y, Geng N, Lin N, Song W et al. Assessing Visceral Obesity and Abdominal Adipose Tissue Distribution in Healthy Populations Based on Computed Tomography: A Large Multicenter Cross-Sectional Study. Front Nutr. 2022;9:871697. https://doi.org/10.3389/fnut.2022.871697.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Kong M, Xu M, Zhou Y, Geng N, Lin N, Song W et al. Assessing Visceral Obesity and Abdominal Adipose Tissue Distribution in Healthy Populations Based on Computed Tomography: A Large Multicenter Cross-Sectional Study. Front Nutr. 2022;9:871697. https://doi.org/10.3389/fnut.2022.871697.</mixed-citation><mixed-citation xml:lang="en">Xue R, Li Q, Geng Y, Wang H, Wang F, Zhang S. Abdominal obesity and risk of CVD: a dose-response meta-analysis of thirty-one prospective studies. Br J Nutr. 2021;126(9):1420–1430. https://doi.org/10.1017/S0007114521000064.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Xue R, Li Q, Geng Y, Wang H, Wang F, Zhang S. Abdominal obesity and risk of CVD: a dose-response meta-analysis of thirty-one prospective studies. Br J Nutr. 2021;126(9):1420–1430. https://doi.org/10.1017/S0007114521000064.</mixed-citation><mixed-citation xml:lang="en">Zheng L, Sun A, Han S, Qi R, Wang R, Gong X, Xue M. Association between visceral obesity and 10-year risk of first atherosclerotic cardiovascular diseases events among American adults: National Health and Nutrition Examination Survey. Front Cardiovasc Med. 2023;10:1249401. https://doi.org/10.3389/fcvm.2023.1249401.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Zheng L, Sun A, Han S, Qi R, Wang R, Gong X, Xue M. Association between visceral obesity and 10-year risk of first atherosclerotic cardiovascular diseases events among American adults: National Health and Nutrition Examination Survey. Front Cardiovasc Med. 2023;10:1249401. https://doi.org/10.3389/fcvm.2023.1249401.</mixed-citation><mixed-citation xml:lang="en">Tsygankova OV, Nikolaev KYu, Fedorova EL, Bondareva ZG, Ragino YuI, Platonov DYu, Pustovetova MG. Risk factors of cardiovascular diseases. Look at the woman. Ateroscleroz. 2014;10(1):44–55. (In Russ.) Available at: https://ateroskleroz.elpub.ru/jour/article/view/698.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Цыганкова ОВ, Николаев КЮ, Федорова ЕЛ, Бондарева ЗГ, Рагино ЮИ, Платонов ДЮ, Пустоветова МГ. Факторы риска сердечно-сосудистых заболеваний. взгляд на женщину. Атеросклероз. 2014;10(1):44–55. Режим доступа: https://ateroskleroz.elpub.ru/jour/article/view/698.</mixed-citation><mixed-citation xml:lang="en">Lloyd-Jones DM. Cardiovascular risk prediction: basic concepts, current status, and future directions. Circulation. 2010;121(15):1768–1777. https://doi.org/10.1161/CIRCULATIONAHA.109.849166.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Lloyd-Jones DM. Cardiovascular risk prediction: basic concepts, current status, and future directions. Circulation. 2010;121(15):1768–1777. https://doi.org/10.1161/CIRCULATIONAHA.109.849166.</mixed-citation><mixed-citation xml:lang="en">Tanriover C, Copur S, Gaipov A, Ozlusen B, Akcan RE, Kuwabara M et al. Metabolically healthy obesity: Misleading phrase or healthy phenotype? Eur J Intern Med. 2023;111:5–20. https://doi.org/10.1016/j.ejim.2023.02.025.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Tanriover C, Copur S, Gaipov A, Ozlusen B, Akcan RE, Kuwabara M et al. Metabolically healthy obesity: Misleading phrase or healthy phenotype? Eur J Intern Med. 2023;111:5–20. https://doi.org/10.1016/j.ejim.2023.02.025.</mixed-citation><mixed-citation xml:lang="en">Suwała S, Junik R. Body Mass Index and Waist Circumference as Predictors of Above-Average Increased Cardiovascular Risk Assessed by the SCORE2 and SCORE2-OP Calculators and the Proposition of New Optimal Cut-Off Values: Cross-Sectional Single-Center Study. J Clin Med. 2024;13(7):1931. https://doi.org/10.3390/jcm13071931.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Suwała S, Junik R. Body Mass Index and Waist Circumference as Predictors of Above-Average Increased Cardiovascular Risk Assessed by the SCORE2 and SCORE2-OP Calculators and the Proposition of New Optimal Cut-Off Values: Cross-Sectional Single-Center Study. J Clin Med. 2024;13(7):1931. https://doi.org/10.3390/jcm13071931.</mixed-citation><mixed-citation xml:lang="en">Semmler G, Balcar L, Wernly S, Völkerer A, Semmler L, Hauptmann L et al. Insulin resistance and central obesity determine hepatic steatosis and explain cardiovascular risk in steatotic liver disease. Front Endocrinol. 2023;14:1244405. https://doi.org/10.3389/fendo.2023.1244405.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Semmler G, Balcar L, Wernly S, Völkerer A, Semmler L, Hauptmann L et al. Insulin resistance and central obesity determine hepatic steatosis and explain cardiovascular risk in steatotic liver disease. Front Endocrinol. 2023;14:1244405. https://doi.org/10.3389/fendo.2023.1244405.</mixed-citation><mixed-citation xml:lang="en">Byambasukh O, Eisenga MF, Gansevoort RT, Bakker SJ, Corpeleijn E. Body fat estimates from bioelectrical impedance equations in cardiovascular risk assessment: The PREVEND cohort study. Eur J Prev Cardiol. 2019;26(9):905–916. https://doi.org/10.1177/2047487319833283.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Byambasukh O, Eisenga MF, Gansevoort RT, Bakker SJ, Corpeleijn E. Body fat estimates from bioelectrical impedance equations in cardiovascular risk assessment: The PREVEND cohort study. Eur J Prev Cardiol. 2019;26(9):905–916. https://doi.org/10.1177/2047487319833283.</mixed-citation><mixed-citation xml:lang="en">Bellan M, Menegatti M, Ferrari C, Carnevale Schianca GP, Pirisi M. Ultrasound-assessed visceral fat and associations with glucose homeostasis and cardiovascular risk in clinical practice. Nutr Metab Cardiovasc Dis. 2018;28(6):610–617. https://doi.org/10.1016/j.numecd.2018.01.006.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Bellan M, Menegatti M, Ferrari C, Carnevale Schianca GP, Pirisi M. Ultrasound-assessed visceral fat and associations with glucose homeostasis and cardiovascular risk in clinical practice. Nutr Metab Cardiovasc Dis. 2018;28(6):610–617. https://doi.org/10.1016/j.numecd.2018.01.006.</mixed-citation><mixed-citation xml:lang="en">Bellan M, Menegatti M, Ferrari C, Carnevale Schianca GP, Pirisi M. Ultrasound-assessed visceral fat and associations with glucose homeostasis and cardiovascular risk in clinical practice. Nutr Metab Cardiovasc Dis. 2018;28(6):610–617. https://doi.org/10.1016/j.numecd.2018.01.006.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
