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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/ms2025-210</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-9285</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ШКОЛА ПЕДИАТРА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PEDIATRICIAN SCHOOL</subject></subj-group></article-categories><title-group><article-title>Клинический случай эозинофильного эзофагита у ребенка</article-title><trans-title-group xml:lang="en"><trans-title>A clinical case of eosinophilic esophagitis in a child</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2847-6268</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бережная</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Berezhnaya</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бережная Ирина Владимировна - к.м.н., доцент кафедры педиатрии имени академика Г.Н. Сперанского, РМАНПО; врач-педиатр, гастроэнтеролог, Детская ГКБ им. З.А. Башляевой.</p><p>123242, Москва, ул. Баррикадная, д. 2/1; 125373, Москва, ул. Героев Панфиловцев, д. 28</p></bio><bio xml:lang="en"><p>Irina V. Berezhnaya - Cand. Sci. (Med.), Associate Professor, Department of Pediatrics named after Academician G.N. Speransky, Russian Medical Academy of Continuous Professional Education; Pediatrician, Gastroenterologist, Children’s City Clinical Hospital named after Z.A. Bashlayeva.</p><p>2/1, Bldg. 1, Barrikadnaya St., Moscow, 125993; 28, Geroev Panfilovtsev St., Moscow, 125373</p></bio><email xlink:type="simple">berezhnaya-irina26@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4200-4598</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Захарова</surname><given-names>И. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Zakharova</surname><given-names>I. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Захарова Ирина Николаевна - д.м.н., профессор, заслуженный врач России, заведующая кафедрой педиатрии имени академика Г.Н. Сперанского.</p><p>123242, Москва, ул. Баррикадная, д. 2/1</p></bio><bio xml:lang="en"><p>Irina N. Zakharova - Dr. Sci. (Med.), Professor, Honored Doctor of Russia, Head of the Department of Pediatrics named after Academician G.N. Speransky, Russian Medical Academy of Continuous Professional Education.</p><p>2/1, Bldg. 1, Barrikadnaya St., Moscow, 125993</p></bio><email xlink:type="simple">zakharova-rmapo@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1695-0978</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Камилова</surname><given-names>А. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Kamilova</surname><given-names>A. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Камилова Алтиной Турсуновна - д.м.н., профессор, руководитель отдела гастроэнтерологии.</p><p>100179, Ташкент, ул. 2-й Чимбай, проезд Талант, д. 3</p></bio><bio xml:lang="en"><p>Altinoy T. Kamilova - Dr. Sci. (Med.), Professor, Head of the Gastroenterology Department, Republican Specialized Scientific and Practical Medical Center of Pediatrics.</p><p>3, 2nd Chimbay St., Talant Passage, Tashkent, 100179</p></bio><email xlink:type="simple">okamilova@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-0312-9929</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гофурова</surname><given-names>З. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Gofurova</surname><given-names>Z. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гофурова Зилола Бахтияровна - младший научный сотрудник отдела гастроэнтерологии.</p><p>100179, Ташкент, ул. 2-й Чимбай, проезд Талант, д. 3</p></bio><bio xml:lang="en"><p>Zilola B. Gofurova - Junior Researcher, Gastroenterology Department, Republican Specialized Scientific and Practical Medical Center of Pediatrics.</p><p>3, 2nd Chimbay St., Talant Passage, Tashkent, 100179</p></bio><email xlink:type="simple">zilolagofurova28@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-6747-5982</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Убайходжаева</surname><given-names>Х. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Ubaykhodzhaeva</surname><given-names>Kh. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Убайходжаева Хилола Турапходжаевна - врач, ординатор отделения гастроэнтерологии.</p><p>100179, Ташкент, ул. 2-й Чимбай, проезд Талант, д. 3</p></bio><bio xml:lang="en"><p>Khilola T. Ubaykhodzhaeva - Resident Doctor, Department of Gastroenterology, Republican Specialized Scientific and Practical Medical Center of Pediatrics.</p><p>3, 2nd Chimbay St., Talant Passage, Tashkent, 100179</p></bio><email xlink:type="simple">ms.hilolahon@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-9412-5435</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тожибоев</surname><given-names>А. Ш.</given-names></name><name name-style="western" xml:lang="en"><surname>Tojiboev</surname><given-names>A. Sh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тожибоев Абдулаазиз Шавкатович - врач-гастроэнтеролог.</p><p>100179, Ташкент, ул. 2-й Чимбай, проезд Талант, д. 3</p></bio><bio xml:lang="en"><p>Abdulaziz Sh. Tojiboev - Doctor, Gastroenterologist, Republican Specialized Scientific and Practical Medical Center of Pediatrics.</p><p>3, 2nd Chimbay St., Talant Passage, Tashkent, 100179</p></bio><email xlink:type="simple">bek.8293@gmail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российская медицинская академия непрерывного профессионального образования; Детская городская клиническая больница имени З.А. Башляевой</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Continuous Professional Education; Children’s City Clinical Hospital named after Z.A. Bashlayeva</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Российская медицинская академия непрерывного профессионального образования</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Continuous Professional Education</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Республиканский специализированный научно-практический медицинский центр педиатрии</institution><country>Узбекистан</country></aff><aff xml:lang="en"><institution>Republican Specialized Scientific and Practical Medical Center of Pediatrics</institution><country>Uzbekistan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>02</day><month>08</month><year>2025</year></pub-date><volume>0</volume><issue>11</issue><fpage>178</fpage><lpage>187</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бережная И.В., Захарова И.Н., Камилова А.Т., Гофурова З.Б., Убайходжаева Х.Т., Тожибоев А.Ш., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Бережная И.В., Захарова И.Н., Камилова А.Т., Гофурова З.Б., Убайходжаева Х.Т., Тожибоев А.Ш.</copyright-holder><copyright-holder xml:lang="en">Berezhnaya I.V., Zakharova I.N., Kamilova A.T., Gofurova Z.B., Ubaykhodzhaeva K.T., Tojiboev A.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/9285">https://www.med-sovet.pro/jour/article/view/9285</self-uri><abstract><p>Эозинофильный эзофагит – редкое хроническое воспалительное заболевание пищевода, внесенное в список орфанных и редких заболеваний МЗ РФ в 2024 г. В последние годы заболевание приобретает все большую значимость в клинической практике, особенно в педиатрии, т. к. его распространенность стремительно растет во всем мире. По данным литературы, эозинофильный эзофагит связан с аллергическими заболеваниями, такими как пищевая аллергия, атопический дерматит, бронхиальная астма и аллергический ринит, и представляет собой существенное клиническое и диагностическое затруднение из-за сходства симптомов с гастроэзофагеальной рефлюксной болезнью. Такие малоспецифичные симптомы, как срыгивания, тошнота и рвота, боли в животе во время еды наблюдаются у детей раннего возраста, жалобы на дисфагию отмечены у детей старшего возраста. Диагностика эозинофильного эзофагита – достаточно сложная задача из-за отсутствия специфических симптомов и маркеров, а также необходимости инвазивного подтверждения через эндоскопию и биопсию. Это приводит к частым случаям недооценки или запоздалой постановке диагноза, что, в свою очередь, может ухудшать прогноз и качество жизни пациентов. В статье приводятся клинические случаи эозинофильного эзофагита у детей младшего возраста с оценкой признаков, диагностическим поиском и принципами выбора терапии.</p></abstract><trans-abstract xml:lang="en"><p>Eosinophilic esophagitis is a rare chronic inflammatory disease of the esophagus, which is entered into the list of orphan and rare diseases of the Ministry of Health of the Russian Federation in 2024. In recent years, the disease has become increasingly important in clinical practice, especially in pediatrics, as its prevalence is rapidly growing throughout the world. It is reported that eosinophilic esophagitis is associated with allergic diseases such as food allergy, atopic dermatitis, bronchial asthma and allergic rhinitis, and represents a significant clinical and diagnostic challenge due to the similarity of symptoms with gastroesophageal reflux disease. Such non-specific symptoms as regurgitation, nausea and vomiting, abdominal pain while eating are observed in young children, and complaints of dysphagia are registered in older children. It is quite difficult to diagnose eosinophilic esophagitis due to the lack of specific symptoms and markers, as well as the need for invasive diagnosis confirmation using endoscopy and biopsy examinations. This results in frequent cases of understaging or late diagnosis, which, in turn, can worsen the prognosis and patient’s quality of life. The article presents clinical cases of eosinophilic esophagitis in young children, assessment of symptoms, diagnostic search, and principles of therapy choice.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дети</kwd><kwd>эозинофильные заболевания желудочно-кишечного тракта</kwd><kwd>дисфагия</kwd><kwd>эозинофильный эзофагит</kwd><kwd>терапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>children</kwd><kwd>eosinophilic gastrointestinal diseases</kwd><kwd>dysphagia</kwd><kwd>eosinophilic esophagitis</kwd><kwd>therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Alsohaibani FI, Peedikayil MC, Alzahrani MA, Azzam NA, Almadi MA, Dellon ES, Al-Hussaini AA. Eosinophilic esophagitis: Current concepts in diagnosis and management. 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