medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/ms2025-430medsovet-9461Research ArticleЗАБОЛЕВАНИЯ ПИЩЕВОДА И ЖЕЛУДКАESOPHAGEAL AND GASTRIC DISEASESОпросник «ГеФест» – новые возможности диагностики ГЭРБ и функциональной диспепсии“GeFest” questionnaire: New diagnostic options for GERD and functional dyspepsiahttps://orcid.org/0000-0002-6151-2021БакулинИ. Г.BakulinI. G.

Бакулин Игорь Геннадьевич - д.м.н., профессор, директор Института терапии, заведующий кафедрой пропедевтики внутренних болезней, гастроэнтерологии и диетологии имени С.М. Рысса.

195067, Санкт-Петербург, Пискаревский пр., д. 47

Igor G. Bakulin - Dr. Sci. (Med.), Professor, Director of the Institute of Therapy, Head of the Chair of the Propedeutics of Internal Diseases, Gastroenterology and Dietology n.a. S.M. Riss, North-Western State Medical University named after I.I. Mechnikov.

47, Piskarevskij Prospect, St Petersburg, 195067

igor.bakulin@szgmu.ruhttps://orcid.org/0000-0003-4075-4096БакулинаН. В.BakulinaN. V.

Бакулина Наталья Валерьевна - д.м.н., профессор, заведующая кафедрой внутренних болезней, нефрологии, общей и клинической фармакологии с курсом фармации.

195067, Санкт-Петербург, Пискаревский пр., д. 47

Natalia V. Bakulina - Dr. Sci. (Med.), Professor, Head of the Department of Internal Medicine, Nephrology, General and Clinical Pharmacology with a Pharmacy Course, North-Western State Medical University named after I.I. Mechnikov.

47, Piskarevskij Prospect, St Petersburg, 195067

natalya.bakulina@szgmu.ruhttps://orcid.org/0000-0003-3999-6848ТопаловаЮ. Г.TopalovaYu. G.

Топалова Юлия Геннадьевна - ассистент кафедры внутренних болезней, нефрологии, общей и клинической фармакологии с курсом фармации.

195067, Санкт-Петербург, Пискаревский пр., д. 47

Yulia G. Topalova - Assistant, Department of Internal Medicine, Nephrology, General and Clinical Pharmacology with a Pharmacy Course, North-Western State Medical University named after I.I. Mechnikov.

47, Piskarevskij Prospect, St Petersburg, 195067

topalova.julias@yandex.ruhttps://orcid.org/0000-0001-5720-3528ТихоновС. В.TikhonovS. V.

Тихонов Сергей Викторович - д.м.н., профессор кафедры внутренних болезней, нефрологии, общей и клинической фармакологии с курсом фармации.

195067, Санкт-Петербург, Пискаревский пр., д. 47

Sergey V. Tikhonov - Dr. Sci. (Med.), Professor, Department of Internal Medicine, Nephrology, General and Clinical Pharmacology with a Pharmacy Course, North-Western State Medical University named after I.I. Mechnikov.

47, Piskarevskij Prospect, St Petersburg, 195067

sergeyvt2702@gmail.comhttps://orcid.org/0000-0002-8909-8707ПавловаН. В.PavlovaN. V.

Павлова Надежда Викторовна - к.м.н., медицинский отдел.

115035, Москва, Овчинниковская наб., д. 20, стр. 1

Nadezhda V. Pavlova - Cand. Sci. (Med.), Medical Department, Dr. Reddy’s Laboratories Ltd.

20, Bldg. 1, Ovchinnikovskaya Emb., St Petersburg, 115035

Nadezhda.Pavlova@drreddys.comСеверо-Западный государственный медицинский университет имени И.И. МечниковаРоссияNorth-Western State Medical University named after I.I. MechnikovRussian FederationООО «Др. Редди’c Лабораторис»РоссияDr. Reddy’s Laboratories LtdRussian Federation2025171020250152840Copyright © Бакулин И.Г., Бакулина Н.В., Топалова Ю.Г., Тихонов С.В., Павлова Н.В., 20252025Бакулин И.Г., Бакулина Н.В., Топалова Ю.Г., Тихонов С.В., Павлова Н.В.Bakulin I.G., Bakulina N.V., Topalova Y.G., Tikhonov S.V., Pavlova N.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/9461Введение

Введение. Гастроэзофагеальная рефлюксная болезнь (ГЭРБ) и функциональная диспепсия (ФД) – наиболее распространенные заболевания верхних отделов желудочно-кишечного тракта (ЖКТ). По данным литературы, распространенность ГЭРБ в мире составляет 5–25%, в России – 11–24%. ФД выявляется примерно у 20% популяции. Синдром диспепсии присутствует примерно у 40% пациентов с ГЭРБ.

Цель

Цель. Разработать опросник «ГеФест» для выявления изолированных и сочетанных форм ГЭРБ и ФД; оценить его чувствительность, специфичность и удобство применения.

Материалы и методы

Материалы и методы. В наблюдательном исследовании приняло участие 208 пациентов (67 мужчин и 141 женщина) в возрасте 18–65 лет. Участники исследования ежедневно на протяжении 7 дней заполняли разработанный опросник «ГеФест». Пациентам проводилось лабораторно-инструментальное обследование, включавшее эзофагогастродуоденоскопию (ЭГДС) и суточную рН-импедансометрию верхних отделов ЖКТ. На основании сопоставления результатов анкетирования и обследования определялась валидность разработанного опросника.

Результаты

Результаты. В исследовании была продемонстрирована высокая чувствительность и специфичность опросника на уровне 90–100%. Опросник эффективно выявлял изолированные и сочетанные формы ГЭРБ и ФД. Участники исследования тратили около одной минуты на заполнение опросника. Врачи и пациенты высоко оценили удобство применения опросника.

Выводы

Выводы. Опросник «ГеФест» является эффективным и надежным инструментом диагностики и динамического мониторинга ГЭРБ и ФД. Использование опросника может способствовать снижению затрат на диагностику данных заболеваний верхних отделов ЖКТ, включая сочетанные формы, уменьшить потребность в инвазивных процедурах и облегчить выбор лекарственной терапии.

Introduction

Introduction. Gastroesophageal reflux disease (GERD) and functional dyspepsia (FD) are the most common diseases of the upper gastrointestinal tract (GIT). According to the literature, the prevalence of GERD in the world is 5–25%, in Russia – from 12% to 24%. Symptoms of GERD in patients with FD are observed in 1.6–8% of cases, and in some studies – up to 37%. FD is found in approximately 20% of the population. Dyspepsia syndrome is present in approximately 40% of patients with GERD.

Aim

Aim. To develop the “GeFest” questionnaire to identify isolated and combined forms of GERD and FD, and to evaluate its sensitivity, specificity, and application conveniences.

Materials and methods

Materials and methods. 208 patients (67 men and 141 women) aged 18–65 years participated in the observational study. Participants completed the “GeFest” questionnaire daily for 7 days. Patients underwent laboratory and instrumental examinations, including esophagogastroduodenoscopy (EGDS) and 24-hour pH-impedancemetry of the upper gastrointestinal tract. The validity of the developed questionnaire was determined by comparing the questionnaire and examination results.

Results

Results. The study demonstrated high sensitivity and specificity of the questionnaire (90–100%). The questionnaire effectively identified isolated and combined forms of GERD and FD. Study participants spent approximately 1 minute completing the questionnaire. Physicians and patients highly rated the questionnaire’s ease of use.

Conclusions

Conclusions. The “GeFest” questionnaire is an effective and reliable tool for the diagnosis and dynamic monitoring of GERD and FD. Use of the questionnaire can help reduce the cost of diagnosing these upper gastrointestinal diseases, including combined forms, reduce the need for invasive procedures, and facilitate the selection of drug therapy.

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The authors declare that there are no conflicts of interest present.