medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/ms2025-422medsovet-9552Research ArticleПРАКТИКАPRACTICEОсобенности психоэмоционального состояния у пациентов с ольфакторной дисфункциейFeatures of the psychoemotional state of patients with olfactory dysfunctionhttps://orcid.org/0000-0002-9697-2597ЛебедеваГ. В.LebedevaG. V.

Лебедева Гая Валерьевна, ассистент кафедры болезней уха, горла и носа

119991, Москва, ул. Большая Пироговская, д. 6, стр. 1

Gaya V. Lebedeva, Assistant for Ear, Nose and Throat Department

6, Bldg. 1, Bolshaya Pirogovskaya St., Moscow, 119991

gde12@yandex.ruhttps://orcid.org/0000-0002-8552-1395СвистушкинМ. В.SvistushkinM. V.

Свистушкин Михаил Валерьевич, доцент кафедры болезней уха, горла и носа

119991, Москва, ул. Большая Пироговская, д. 6, стр. 1

Mikhail V. Svistushkin, Associate Professor for Ear, Nose and Throat Department

6, Bldg. 1, Bolshaya Pirogovskaya St., Moscow, 119991

swistushkin@yandex.ruhttps://orcid.org/0000-0003-3386-289XМальцевА. Б.MaltsevA. B.

Мальцев Александр Борисович, ассистент кафедры болезней уха, горла и 

119991, Москва, ул. Большая Пироговская, д. 6, стр. 1

Aleksandr B. Maltsev, Assistant for Ear, Nose and Throat Department

6, Bldg. 1, Bolshaya Pirogovskaya St., Moscow, 119991

maltsev_ab@mail.ruhttps://orcid.org/0000-0001-7414-1293СвистушкинВ. М.SvistushkinV. M.

Свистушкин Валерий Михайлович, заведующий кафедрой болезней уха, горла и носа

119991, Москва, ул. Большая Пироговская, д. 6, стр. 1

Valeriy M. Svistushkin, Head for the Ear, Nose and Throat Department

6, Bldg. 1, Bolshaya Pirogovskaya St., Moscow, 119991

svvm3@yandex.ruhttps://orcid.org/0000-0002-7343-7655КудрявцеваВ. А.KudryavtsevaV. A.

Кудрявцева Варвара Алексеевна, студент

119991, Москва, ул. Большая Пироговская, д. 6, стр. 1

Varvara A. Kudryavtseva, Student

6, Bldg. 1, Bolshaya Pirogovskaya St., Moscow, 119991

kudryavtseva_v_a@student.sechenov.ruhttps://orcid.org/0000-0003-1221-5589ВладимироваТ. Ю.VladimirovaT. Yu.

Владимирова Татьяна Юльевна, заведующая кафедрой и клиникой оториноларингологии имени академика И.Б. Солдатова

443099, Самара, ул. Чапаевская, д. 89

Tatyana Yu. Vladimirova, Head of the Department and Clinic of Otolaryngology of Academician I.B. Soldatov

89, Chapaevskaya St., Samara, 443099

t.yu.vladimirovalor@samsmu.ruhttps://orcid.org/0000-0002-8385-6407КуренковА. В.KurenkovA. V.

Куренков Александр Валерьевич, ассистент кафедры оториноларингологии имени академика И.Б. Солдатова

443099, Самара, ул. Чапаевская, д. 89

Alexandr V. Kurenkov, Assistant Department of Otolaryngology of Academician I.B. Soldatov

89, Chapaevskaya St., Samara, 443099

a.v.kurenkov@samsmu.ruhttps://orcid.org/0000-0001-7085-5264МашковаТ. А.MashkovaT. A.

Машкова Тамара Александровна, профессор кафедры оториноларингологии

394036, Воронеж, ул. Студенческая, д. 10

Tamara A. Mashkova, Professor of the Department of Otorhinolaryngology

10, Studencheskaya St., Voronezh, 394036

mashkova-ta@mail.ruПервый Московский государственный медицинский университет имени И.М. Сеченова (Сеченовский Университет)РоссияSechenov First Moscow State Medical University (Sechenov University)Russian FederationСамарский государственный медицинский университетРоссияSamara State Medical UniversityRussian FederationВоронежский государственный медицинский университет имени Н.Н. БурденкоРоссияBurdenko Voronezh State Medical UniversityRussian Federation202520112025018161169Copyright © Лебедева Г.В., Свистушкин М.В., Мальцев А.Б., Свистушкин В.М., Кудрявцева В.А., Владимирова Т.Ю., Куренков А.В., Машкова Т.А., 20252025Лебедева Г.В., Свистушкин М.В., Мальцев А.Б., Свистушкин В.М., Кудрявцева В.А., Владимирова Т.Ю., Куренков А.В., Машкова Т.А.Lebedeva G.V., Svistushkin M.V., Maltsev A.B., Svistushkin V.M., Kudryavtseva V.A., Vladimirova T.Y., Kurenkov A.V., Mashkova T.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/9552Введение

Введение. В зарубежных исследованиях дизосмия чаще рассматривается как маркер для выявления различных патологий. Неоднозначным остается вопрос, может ли расстройство обоняния выступать в роли этиологического фактора и оказывать влияние на возникновение патологических психоэмоциональных состояний (тревожность, депрессия).

Цель

Цель. Оценить взаимосвязь между выраженностью ольфакторной дисфункции и изменением психоэмоционального состояния (депрессия, тревожное расстройство).

Материалы и методы

Материалы и методы. В исследовании приняло участие 60 пациентов. В соответствии с нозологией пациенты были разделены на 3 группы: полипозный риносинусит (n = 23); посттравматическая (n = 10) и постинфекционная дисфункция обоняния (n = 27). Перед проведением исследования у всех пациентов проведена оценка идентификационной способности обоняния отечественным обонятельным тестом. В исследование включены пациенты, у которых по результатам теста выявлена ольфакторная дисфункция: идентификационная способность обоняния < 16 баллов. В качестве метода диагностики депрессии и тревожности применялись: опросник PHQ-9 (Patient Health Questionnaire 9) и шкала GAD-7 (Generalized Anxiety Disorder 7).

Результаты

Результаты. При анализе полученных данных по всей выборке пациентов с применением корреляции по Спирмену выявлено наличие взаимосвязи между выраженностью ольфакторной дисфункции и изменением психоэмоционального состояния (депрессия – rs = -0,388, p < 0,01; тревожность – rs = -0,275, p = 0,034). В группах пациентов по каждой нозологии также получены статистически значимые результаты: полипозный риносинусит – rs = -0,485, p = 0,019; постинфекционная дисфункция обоняния – rs = -0,501, р < 0,01; посттравматическая дисфункция обоняния – rs = -0,945, p < 0,001. Аналогичные результаты выявлены и у пациентов с симптомами тревоги: полипозный риносинусит – rs = -0,46, p = 0,027; постинфекционная дисфункция – rs = -0,52, p < 0,01 и посттравматическая дисфункция – rs = -0,73, p = 0,017.

Выводы

Выводы. Полученные данные обосновывают клиническую значимость комплексного обследования пациентов с нарушением обоняния с применением валидированных шкал оценки симптомов депрессии и тревоги.

Introduction

Introduction. In foreign studies, dysosmia is more often considered as a marker for for diagnostics various pathologies. The question of whether olfactory disorder can act as an etiological factor and influence the occurrence of pathological psychoemotional states (anxiety, depression) remains ambiguous.

Aim

Aim. Тo assess the correlation between the severity of olfactory dysfunction and changes in the psychoemotional state (depression, anxiety disorder).

Materials and methods

Materials and methods. 60 patients participated in this study. According to the nosology, the patients were divided into 3 groups: polypous rhinosinusitis (n = 23); post-traumatic (n = 10) and post-infectious olfactory dysfunction (n = 27). Before the study, all patients underwent an assessment of their olfactory identification ability using a Russian olfactory test. The study included patients who, according to the test results: olfactory identification ability < 16 points. The PHQ-9 (Patient Health Questionnaire 9) and the GAD-7 (Generalized Anxiety Disorder 7) were used as a method for diagnosing depression and anxiety.

Results

Results. When analyzing the obtained data for the entire sample of patients using Spearman correlation, a correlation was found between the severity of olfactory dysfunction and changes in the psychoemotional state (depression rs = -0.388, p < 0.01; anxiety rs = -0.275, p = 0.034). Statistically significant results were also obtained in groups of patients for each nosology: polypous rhinosinusitis rs = -0.485, p = 0.019; post-infectious olfactory dysfunction rs = -0.501, p < 0.01; post-traumatic olfactory dysfunction rs = -0.945, p < 0.001. Similar results were found in patients with anxiety symptoms: polypous rhinosinusitis rs = -0.46, p = 0.027; post-infectious dysfunction rs = -0.52, p < 0.01 and post-traumatic dysfunction rs = -0.73, p = 0.017.

Conclusions

Conclusions. The obtained data substantiate the clinical significance of a comprehensive examination of patients with olfactory disorders using validated scales for assessing symptoms of depression and anxiety.

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The authors declare that there are no conflicts of interest present.