medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/ms2026-032medsovet-9889Research ArticleБРОНХОПУЛЬМОНОЛОГИЯ И ОТОЛАРИНГОЛОГИЯBRONCHOPULMONOLOGY, OTORHINOLARYNGOLOGYЭффективность витаминно-минерального комплекса из порошка рогов северного оленя у детей, перенесших COVID-19Efficacy of deer antler powder vitamin-mineral supplement in children who have had COVID-19 infectionhttps://orcid.org/0000-0002-5865-8046ОсовецкаяЮ. Л.OsovetskayaYu. L.

Осовецкая Юлиана Леонидовна - ассистент кафедры пропедевтики детских болезней Клинического института детского здоровья имени Н.Ф. Филатова.

119991, Москва, ул. Трубецкая, д. 8, стр. 2

Yuliana L. Osovetskaya - Assistant of the Department of Propaedeutics of Childhood Diseases, Clinical Institute of Child Health named after N.F. Filatov, Sechenov First Moscow State Medical University (Sechenov University).

8, Bldg. 2, Trubetskaya St., Moscow, 119991

yuliana.osovetskaya@yandex.ruhttps://orcid.org/0000-0002-8307-5168СамолыгоИ. С.SamolygoI. S.

Самолыго Иван Сергеевич - стажер-исследователь кафедры пропедевтики детских болезней Клинического института детского здоровья имени Н.Ф. Филатова.

119991, Москва, ул. Трубецкая, д. 8, стр. 2

Ivan S. Samolygo - Researcher-Trainee, Department of Propaedeutics of Childhood Diseases, Clinical Institute of Child Health named after N.F. Filatov, Sechenov First Moscow State Medical University (Sechenov University).

8, Bldg. 2, Trubetskaya St., Moscow, 119991

ivan.samolygo.03@bk.ruhttps://orcid.org/0009-0001-4321-5613КучерукД. А.KucherukD. A.

Кучерук Дарья Александровна - студент педиатрического факультета.

119991, Москва, ул. Трубецкая, д. 8, стр. 2

Daria A. Kucheruk - Student, Faculty of Pediatrics, Sechenov First Moscow State Medical University (Sechenov University).

8, Bldg. 2, Trubetskaya St., Moscow, 119991

Daria.ku4eruk@gmail.comhttps://orcid.org/0009-0009-6286-0149ЗайцеваП. С.ZaitsevaP. S.

Зайцева Полина Сергеевна - студент педиатрического факультета.

119991, Москва, ул. Трубецкая, д. 8, стр. 2

Polina S. Zaitseva - Student, Faculty of Pediatrics, Sechenov First Moscow State Medical University (Sechenov University).

8, Bldg. 2, Trubetskaya St., Moscow, 119991

polinazayceva2005@gmail.comhttps://orcid.org/0009-0002-6001-8897АгаповаА. А.AgapovaA. A.

Агапова Арина Алексеевна - студент педиатрического факультета.

119991, Москва, ул. Трубецкая, д. 8, стр. 2

Arina A. Agapova - Student, Faculty of Pediatrics, Sechenov First Moscow State Medical University (Sechenov University).

8, Bldg. 2, Trubetskaya St., Moscow, 119991

arinaagapova2003@gmail.comhttps://orcid.org/0009-0001-2123-2033НагиеваГ. Г.NagievaG. G.

Нагиева Гюнаш Габил кызы - студент педиатрического факультета.

119991, Москва, ул. Трубецкая, д. 8, стр. 2

Gunash G. Nagieva - Student, Faculty of Pediatrics, Sechenov First Moscow State Medical University (Sechenov University).

8, Bldg. 2, Trubetskaya St., Moscow, 119991

gynash.nagieva@internet.ruhttps://orcid.org/0000-0003-0876-6548МацукатоваБ. О.MatsukatovaB. O.

Мацукатова Белла Одиссевна - к.м.н., доцент кафедры пропедевтики детских болезней Клинического института детского здоровья имени Н.Ф. Филатова.

119991, Москва, ул. Трубецкая, д. 8, стр. 2

Bella O. Matsukatova - Cand. Sci. (Med.), Associate Professor, Department of Propaedeutics of Childhood Diseases, Clinical Institute of Child Health named after N.F. Filatov, Sechenov First Moscow State Medical University (Sechenov University).

8, Bldg. 2, Trubetskaya St., Moscow, 119991

matsukatova_b_o@staff.sechenov.ruhttps://orcid.org/0000-0001-5601-0994КильдияроваР. Р.KildiyarovaR. R.

Кильдиярова Рита Рафгатовна - д.м.н., профессор, профессор кафедры пропедевтики детских болезней Клинического института детского здоровья имени Н.Ф. Филатова.

119991, Москва, ул. Трубецкая, д. 8, стр. 2

Rita R. Kildiyarova - Dr. Sci. (Med.), Professor, Department of Propaedeutics of Childhood Diseases, Clinical Institute of Child Health named after N.F. Filatov, Sechenov First Moscow State Medical University (Sechenov University).

8, Bldg. 2, Trubetskaya St., Moscow, 119991

kildiyarova@mail.ruhttps://orcid.org/0000-0001-8689-7602ЭрдесС. И.ErdesS. I.

Эрдес Светлана Ильинична - д.м.н., профессор, заведующая кафедрой пропедевтики детских болезней Клинического института детского здоровья имени Н.Ф. Филатова.

119991, Москва, ул. Трубецкая, д. 8, стр. 2

Svetlana I. Erdes - Dr. Sci. (Med.), Professor, Head of the Department of Propaedeutics of Childhood Diseases, Clinical Institute of Child Health named after N.F. Filatov, Sechenov First Moscow State Medical University (Sechenov University).

8, Bldg. 2, Trubetskaya St., Moscow, 119991

erdes_s_i@staff.sechenov.ruПервый Московский государственный медицинский университет имени И.М. Сеченова (Сеченовский Университет)РоссияSechenov First Moscow State Medical University (Sechenov University)Russian Federation202624032026018896Copyright © Осовецкая Ю.Л., Самолыго И.С., Кучерук Д.А., Зайцева П.С., Агапова А.А., Нагиева Г.Г., Мацукатова Б.О., Кильдиярова Р.Р., Эрдес С.И., 20262026Осовецкая Ю.Л., Самолыго И.С., Кучерук Д.А., Зайцева П.С., Агапова А.А., Нагиева Г.Г., Мацукатова Б.О., Кильдиярова Р.Р., Эрдес С.И.Osovetskaya Y.L., Samolygo I.S., Kucheruk D.A., Zaitseva P.S., Agapova A.A., Nagieva G.G., Matsukatova B.O., Kildiyarova R.R., Erdes S.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/9889Введение

Введение. Отсутствие единых патогенетически обоснованных протоколов терапии и реабилитации детей с постковидным синдромом (ПКС) диктует необходимость поиска новых методов, в частности нутритивной поддержки.

Цель

Цель. Оценить эффективность и безопасность применения витаминно-минерального комплекса из порошка рогов северного оленя у детей, перенесших COVID-19.

Материалы и методы

Материалы и методы. В проспективное открытое сравнительное исследование включено 60 детей 3–17 лет, перенесших инфекцию SARS-CoV-2 не менее чем за 3 мес. Выделены две группы: основная (n = 30) – дети с постковидным синдромом (ПКС) и группа сравнения (n = 30) – реконвалесценты без признаков ПКС. Всем был назначен витаминно-минеральный комплекс из порошка рогов северного оленя (Россия) в течение 60 дней. Для оценки динамики ПКС использовали анкетирование на основе международных опросников и оценки качества жизни детей; клинические, биохимические анализы крови; непараметрические методы статистики.

Результаты

Результаты. В основной группе по завершении курса витаминно-минерального комплекса зафиксирована достоверная положительная динамика по всем симптомам ПКС. Суммарная частота амбулаторных обращений снизилась с 90,0 до 40,0% с редукцией эпизодов респираторных заболеваний. Нарушения качества сна уменьшились с 60,0 до 3,3%. Хроническая утомляемость и низкая толерантность к физическим и когнитивным нагрузкам нивелировались с 66,6 до 10,0%; улучшились эмоциональный статус и академическая успеваемость. Данные опросника KIDSCREEN-27 подтвердили повышение качества жизни. Отмечено достоверное снижение маркера воспаления – СОЭ. У всех детей не выявлено значимого изменения уровня печеночных проб, что может свидетельствовать об отсутствии нарушения функции печени. На протяжении всего периода наблюдения нежелательные явления и аллергические реакции не регистрировались.

Выводы

Выводы. Двухмесячный курс приема витаминно-минерального комплекса продемонстрировал высокую клиническую эффективность, отличную переносимость, благоприятный профиль безопасности в комплексном лечении ПКС у детей.

Introduction

Introduction. The absence of unified pathogenetically substantiated protocols for therapy and rehabilitation of children with post-covid syndrome (PCS) urges healthcare professionals to seek new methods, specifically nutritional support.

Aim

Aim. To evaluate the efficacy and safety of the deer antler powder vitamin-mineral supplement in children who have had COVID-19 infection.

Materials and methods

Materials and methods. A total of 60 children aged 3 to 17 years old who had SARS-CoV-2 at least 3 months earlier were enrolled in the prospective open-label comparative study. The patients were divided into two groups: the treatment group (n = 30) included children with PCS and the comparator group (n = 30) included convalescents without PCS symptoms. All of them were prescribed a deer antler powder vitamin-mineral supplement (Russia) to be taken for 60 days. To assess changes in PCS, international paediatric QoL questionnaires; common blood count, biochemical tests, and nonparametric statistical methods were used.

Results

Results. In the treatment group, a significant improvement in all PCS symptoms was reported after completing the vitamin-mineral supplement course. The total frequency of outpatient visits decreased from 90.0 to 40.0% with a reduction in episodes of respiratory diseases. The sleep disorders decreased from 60.0 to 3.3%. Chronic fatigue and low tolerance to physical and cognitive loads reduced from 66.6 to 10.0%; emotional status and academic performance improved. The KIDSCREEN-27 questionnaire results demonstrated an improvement in quality of life. There was a significant decrease in ESR inflammatory marker. No children showed significant changes in liver function tests, which may suggest the absence of liver dysfunction. No adverse events or allergic reactions were reported throughout the entire period of observation.

Conclusions

Conclusions. The two-month vitamin-mineral supplementation course demonstrated high clinical efficacy, excellent tolerability, and a favourable safety profile in the comprehensive treatment of PCS in children.

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The authors declare that there are no conflicts of interest present.