medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/ms2026-015medsovet-9958Research ArticleКОСМЕТОЛОГИЯCOSMETOLOGYСовременные стратегии ухода за зрелой кожей: роль биотического комплекса и растительных экстрактовModern skincare strategies for aging skin: The role of biotic complexes and plant extractshttps://orcid.org/0000-0001-5936-6232ЗаславскийД. В.ZaslavskyD. V.

Заславский Денис Владимирович, д.м.н., профессор, Заслуженный врач РФ, заведующий кафедрой дерматовенерологии 

194100, Санкт-Петербург, ул. Литовская, д. 2

Denis V. Zaslavsky, Dr. Sci. (Med.), Professor, Honored Doctor of Russian Federation, Head of the Department of Dermatovenereology 

2, Litovskaya St., St Petersburg, 194100

venerology@gmail.comhttps://orcid.org/0000-0001-5056-374XТагановА. В.TaganovA. V.

Таганов Алексей Викторович, д.м.н., профессор, председатель отделения фундаментальной дерматовенерологии и косметологии 

119002, Москва, переулок Сивцев Вражек, д. 29/16

Alexey V. Taganov, Dr. Sci. (Med.), Professor, Chairman of the Department of Fundamental Dermatovenereology and Cosmetology 

29/16, Sivtsev Vrazhek Lane, Moscow, 119002

matis87177@yandex.ruhttps://orcid.org/0000-0002-6942-2880КозловаД. В.KozlovaD. V.

Козлова Дарья Васильевна, врач-дерматовенеролог, ассистент кафедры дерматовенерологии; аспирант кафедры радиологии, хирургии и онкологии 

194100, Санкт-Петербург, ул. Литовская, д. 2; 197758, Санкт-Петербург, пос. Песочный, ул. Ленинградская, д. 70 

Darya V. Kozlova, Dermatovenereologist, Assistant of the Department of Dermatovenereology; Postgraduate Student of the Department of Radiology, Surgery and Oncology 

2, Litovskaya St., St Petersburg, 194100;70, Leningradskaya St., Pesochnyy Settlement, St Petersburg, 197758

dashauchenaya@yandex.ruhttps://orcid.org/0009-0000-3552-0880АбдукаеваН. С.AbdukaevaN. S.

Абдукаева Нелли Сулеймановна, к.м.н., доцент, заведующая кафедрой медицинской биологии 

194100, Санкт-Петербург, ул. Литовская, д. 2

Nelly S. Abdukaeva, Cand. Sci. (Med.), Associate Professor, Head of the Department of Medical Biology 

2, Litovskaya St., St Petersburg, 194100

nellbio@mail.ruhttps://orcid.org/0009-0001-1031-720XАлецкий-МилютинН. Н.Aletskiy-MilyutinN. N.

Алецкий-Милютин Николай Николаевич, медицинский советник, старший специалист направления медицинской поддержки бизнеса 

194294, Санкт-Петербург, дорога в Каменку, д. 62а

Nikolay N. Aletskiy-Milyutin, Medical Advisor, Senior Specialist in the Medical Business Support Department 

62а, the road to Kamenka, St Petersburg, 194294

aletskiy.nn@gmail.comhttps://orcid.org/0009-0005-2676-0723ГородовичА. Н.HaradovichA. N.

Городович Алексей Николаевич, заведующий кожно-венерологическим отделением 

211415, Полоцк, ул. Октябрьская, д. 15

Alexey N. Haradovich, Head of the Department of Dermatovenerology, Polotsk Central City Hospital 

15, Oktyabrskaya St., Polotsk, 211415

gera.doctor@mail.ruhttps://orcid.org/0000-0002-7434-3634ЗаславскаяЕ. Д.ZaslavskayaE. D.

Заславская Елизавета Денисовна, студент 

194100, Санкт-Петербург, ул. Литовская, д. 2

Elizaveta D. Zaslavskaya, Student 

2, Litovskaya St., St Petersburg, 194100

zaslavliza@gmail.comhttps://orcid.org/0009-0005-1932-3373ЛяминаЕ. А.LyaminaЕ. А.

Лямина Екатерина Антоновна, старший лаборант кафедры дерматовенерологии 

194100, Санкт-Петербург, ул. Литовская, д. 2

Ekaterina A. Lyamina, Senior Assistant of the Department of Dermatovenereology 

2, Litovskaya St., St Petersburg, 194100

katerina_lyamina00@mail.ruhttps://orcid.org/0009-0008-3078-0702ПолуэктоваВ. В.PoluektovaV. V.

Полуэктова Виктория Викторовна, студент 

194100, Санкт-Петербург, ул. Литовская, д. 2

Viktoria V. Poluektova, Student 

2, Litovskaya St., St Petersburg, 194100

poluektova.viktoriia31@yandex.ruhttps://orcid.org/0009-0001-4314-7403ЕрофееваЕ. А.ErofeevaE. A.

Ерофеева Елизавета Антоновна, студент 

194100, Санкт-Петербург, ул. Литовская, д. 2

Elizaveta A. Erofeeva, Student 

2, Litovskaya St., St Petersburg, 194100

elizaveta.vorona@yandex.ruСанкт-Петербургский государственный педиатрический медицинский университетРоссияSaint Petersburg State Pediatric Medical UniversityRussian FederationРоссийская академия естественных наукРоссияRussian Academy of Natural SciencesRussian FederationСанкт-Петербургский государственный педиатрический медицинский университет; Российский научный центр радиологии и хирургических технологий имени академика А.М. ГрановаРоссияSaint Petersburg State Pediatric Medical University; Russian Scientific Center of Radiology and Surgical Technologies named after Academician A.M. GranovRussian FederationАО «ВЕРТЕКС»РоссияVERTEX JSCRussian FederationПолоцкая центральная городская больницаБеларусьPolotsk Central City HospitalBelarus20261604202602137144Copyright © Заславский Д.В., Таганов А.В., Козлова Д.В., Абдукаева Н.С., Алецкий-Милютин Н.Н., Городович А.Н., Заславская Е.Д., Лямина Е.А., Полуэктова В.В., Ерофеева Е.А., 20262026Заславский Д.В., Таганов А.В., Козлова Д.В., Абдукаева Н.С., Алецкий-Милютин Н.Н., Городович А.Н., Заславская Е.Д., Лямина Е.А., Полуэктова В.В., Ерофеева Е.А.Zaslavsky D.V., Taganov A.V., Kozlova D.V., Abdukaeva N.S., Aletskiy-Milyutin N.N., Haradovich A.N., Zaslavskaya E.D., Lyamina Е.А., Poluektova V.V., Erofeeva E.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/9958

Введение. Старение кожи основано на взаимодействии множества факторов, среди которых особую роль играет окислительный стресс. Образование активных форм кислорода запускает каскад реакций, провоцирующих деградацию коллагена и дезорганизацию эластина, что способствует проявлению видимых признаков старения. Рациональный уход, включающий мягкое очищение и увлажнение в сочетании с действием активных компонентов, позволяет замедлить процессы старения. Цель. Оценить эффективность линейки средств, сочетающих комбинации биотического комплекса и растительных экстрактов, для ухода за возрастной кожей. Материалы и методы. 30 женщин от 30 до 55 лет (средний возраст – 42,5 года) с возрастными изменениями кожи в течение 21 дня применяли мягкую пенку для очищения, тоник успокаивающий увлажняющий, boost-сыворотку и крем-уход за кожей вокруг глаз, затем в течение 7 дней только пенку и тоник. Еженедельно пациентам проводили аппаратную оценку показателей эпидермального барьера с помощью аппарата Multi Skin Test Center 750/IMATE 6602 (Германия), на 28-й день – оценку удовлетворенности от применения наружных средств (опросник TTSI-10). Результаты. На 0-й день средние значения показателя влажности кожи составляли 41,3 УЕ, уровня себума – 26,1 УЕ, эластичности – 39,2 УЕ. На 21-й день показатели влажности выросли на 35,6%, эластичности – на 21,4%. Динамика уровня себума была незначительной. При этом показатели эпидермального барьера между 21-м и 28-м днями имели минимальные изменения. Визуально участники исследования отмечали уменьшение выраженности пигментации, заполнение мелких морщин. Во время исследования не было зарегистрировано нежелательных явлений. Выводы. Антивозрастной потенциал исследуемой линейки косметических средств основан на комбинированном действии фитоэкстрактов, биотического комплекса и активных увлажняющих компонентов. Значительное улучшение показателей эпидермального барьера, зарегистрированное в данном исследовании, подтверждает необходимость комплексного подхода к уходу за возрастной кожей.

Introduction. Skin aging is a multifactorial process, with oxidative stress playing a particularly crucial role. The formation of reactive oxygen species (ROS) initiates a cascade of reactions leading to collagen degradation and elastin disorganization, thereby contributing to visible signs of aging. A rational skincare approach, incorporating gentle cleansing and hydration combined with active ingredient action, can slow down the aging processes. Aim. To evaluate the efficacy of a skincare line combining a biotic complex and plant extracts in caring for mature skin. Materials and methods. 30 women aged 30 to 55 years (mean age of 42.5 years), exhibiting age-related skin changes. During the 21 days they applied gentle cleansing foam, soothing, moisturizing toner, boost-serum and eye skin care cream and during the following 7 days only foam and toner. Every week there were an assessment of epidermal barrier parameters using the Multi Skin Test Center 750/IMATE 6602 diagnostic system (Germany) and in 28th day of the study satisfaction with the topical products was evaluated via the TTSI-10 questionnaire. Results. At baseline, the average skin hydration level was 41.3 UE, sebum production was 26.1 UE, and elasticity was 39.2 UE. At the 21st day hydration level increased by 35.6%, and elasticity improved by 21.4%. Sebum level showed minimal change. Moreover, the epidermal barrier parameters showed minimal changes between days 21 and 28. Visually, participants reported filling of fine wrinkles and decrease in pigmentation intensity. During the study, no adverse reactions were reported. Conclusions. The anti-aging potential of the studied cosmetic products is based on the synergistic action of plant extracts, a biotic complex, and active moisturizing components. The significant improvements observed in epidermal barrier parameters validate the importance of a comprehensive approach to caring for aging skin.

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The authors declare that there are no conflicts of interest present.