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Медицинский Совет

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СИНДРОМ РАЗДРАЖЕННОГО КИШЕЧНИКА И ЕГО СВЯЗЬ С КИШЕЧНОЙ МИКРОФЛОРОЙ

https://doi.org/10.21518/2079-701X-2017-5-85-92

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Аннотация

В последнее десятилетие наблюдается очень активное изучение огромного микробного сообщества, которое находится в кишечнике человека. Появилась концепция, объясняющая развитие и персистирование симптомов при синдроме раздраженного кишечника  за счет нарушения кишечного  микробного пейзажа. Манипулирование  микрофлорой кишечника представляет новую стратегию для лечения этого полиэтиологического заболевания. Модулирование кишечной бактериальной композиции – при этом увеличиваются полезные (Lactobacilli и Bifidobacteria) и сокращаются патогенные бактерии (Clostridium, Escherichiacoli, Salmonella, Shigella и Pseudomonas) – должно уменьшать симптомы синдрома раздраженного кишечника. В этой концептуальной основе пробиотики являются оптимальным вариантом с точки зрения эффективности и безопасности, а также особое внимание специалистов привлекают пребиотики, синбиотики, антибиотики и фекальная трансплантация.

Об авторах

Е. Ю. Плотникова
Кемеровский государственный медицинский университет
Россия

Доктор медицинских наук,  профессор



Ю. В. Захарова
Кемеровский государственный медицинский университет
Россия

Кандидат медицинских наук



А. С. Сухих
Кемеровский государственный медицинский университет
Россия

Кандидат медицинских наук



Т. Ю. Грачева
Кемеровский государственный медицинский университет
Россия

Доктор медицинских наук, профессор



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