ПРОФИЛАКТИКА ИНСУЛЬТА ПРИ НЕКЛАПАННОЙ ФИБРИЛЛЯЦИИ ПРЕДСЕРДИЙ. О ЧЕМ ГОВОРЯТ РЕЗУЛЬТАТЫ ИССЛЕДОВАНИЯ ROCKET AF

И. С. Явелов

doi:10.21518/2079-701X-2017-12-154-160

ПРОФИЛАКТИКА ИНСУЛЬТА ПРИ НЕКЛАПАННОЙ ФИБРИЛЛЯЦИИ ПРЕДСЕРДИЙ. О ЧЕМ ГОВОРЯТ РЕЗУЛЬТАТЫ ИССЛЕДОВАНИЯ ROCKET AF

И. С. Явелов

https://doi.org/10.21518/2079-701X-2017-12-154-160

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Аннотация

Длительное (неопределенно долгое) применение пероральных антикоагулянтов – наиболее действенный способ медикаментозного предупреждения кардиоэмболических осложнений при фибрилляции предсердий (ФП). Этот подход превосходит по эффективности антиагреганты (как монотерапию ацетилсалициловой кислотой, так и ее сочетание с клопидогрелом). В этом сообщении будут представлены факты, определившие представления о месте одного из пероральных антикоагулянтов прямого действия – ривароксабана – в профилактике кардиоэмболических осложнений у больных с неклапанной ФП. Речь идет о рандомизированном контролируемом исследовании ROCKET AF, результаты которого стали основанием для одобрения ривароксабана к широкому применению при неклапанной ФП.

Ключевые слова

неклапанная фибрилляция предсердий, инсульт, исследование ROCKET AF, ривароксабан

Об авторе

И. С. Явелов

Государственный научно-исследовательский центр профилактической медицины Минздрава России
Россия

д.м.н., в.н.с. отдела клинической кардиологии и молекулярной генетики

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