Preview

Meditsinskiy sovet = Medical Council

Advanced search

MULTIPARAMETRIC ELASTOGRAPHY – PRINCIPLES OF INDIVIDUAL SELECTION IN THE DIFFUSE LIVER DISEASES

https://doi.org/10.21518/2079-701X-2017-15-148-152

Abstract

Aim of the study. Assessment of the capacity of multiparametric elastography (MPE) in the individual selection in diffuse liver diseases. Material and methods. A survey of 235 patients with diffuse liver diseases: 128 (54,5%) men and 107 (45,5%) women. The first group included 64 (27,2%) the patient with steatogepatitis, second – 97 (41,3%) with hepatitis, third – 74 (31,5%) with cirrhosis of the liver. Obligatory examination: transient elastography, compression elastography, elastography with endosonography, shear way elastography. Results. The initial examination of patients the results of the diagnostic accuracy sensitivity and specificity of all types of elastography: AUROC 0,461 to 0,987. Dynamic monitoring of patients to comply with medical advice: AUROC from 0,829 to is 0,997, who did not follow recommendations – 0,775 to 0,840. It helped to introduce the concept of multiparametric elastography (MPE). Conclusions. MPE can be considered as a universal tool for screening liver fibrosis both at the initial stage and in the process of dynamic observation.

 

About the Authors

T. G. Morozova
Smolensk State Medical University, Ministry of Healthcare of Russia
Russian Federation
PhD in medicine


A. V. Borsukov
Smolensk State Medical University, Ministry of Healthcare of Russia
Russian Federation

MD, Prof.



A. O. Bueverov
Institute of professional education in the «First Moscow State Medical University after I.M. Sechenov»
Russian Federation

MD, Prof.



References

1. WFUMB guidelines and recommendations for clinical use of ultrasound elastography: part 3: liver. Ultrasound in Med & Biol, 2015, 41(5): 1161–1179.

2. EFSUMB guidelines and recommendations on the clinical use of liver ultrasound elastography, Update 2017 (Long Version) Ultrashall in Med. 2017, DOI http: // dx.doi.org/10.1055/s – 0043-1030952.

3. Bamber J, Cosgrove D, Dietrich CF, et al. EFSUMB Guidelines and Recommendations on the Clinical Use of Ultrasound Elastography. Part 1: Basic Principles and Technology. Ultraschall in Med, 2013, 34: 169-184.

4. Cosgrove D., Bamber J., Dietrich C.F., et al. EFSUMB Guidelines and Recommendations on the Clinical Use of Ultrasound Elastography. Part 2: Clinical Applications 2013. DOI http: // dx.doi.org/10.1055/s-0033-1335375 Published on-line: 2013.

5. Морозова Т.Г., Борсуков А.В. Эндосонографический мониторинг в комплексной диагностике заболеваний гепатопанкреатодуоденальной зоны и желудка. Клиническая практика, 2014, 2(18): 35-41.

6. Эластография сдвиговой волны: анализ клинических примеров (под редакцией А.В. Борсукова). Смоленск, 2017. 376 с.

7. Морозова Т.Г., Борсуков А.В. Эластография при эндосонографии органов гепатопанкреатодуоденальной зоны: новое направление диагностики. Ученые записки Орловского государственного университета, 2014, 3 (59): 239-243.

8. Борсуков А.В., Амосов В.И., Бусько Е.А., Баранник Е.А., Васильева Ю.Н., Данзанова Т.Ю., Дынник О.Б., Иванов Ю.В., Ковалев А.В., Линская А.В., Мамошин А.В., Марусенко А.И., Морозова Т.Г., Рахимжанова Сафронова М.А., Синюкова Г.Т., Смысленова М.В., Фазылова С.А. Рекомендации по стандартизированной методике компрессионной эластографии молочной железы, щитовидной железы, регионарных лимфатических узлов, внеорганных образований и при эндосонографии (учебное пособие). Смоленск: ПНИЛ СГМУ, 2015. 36 с.

9. Ferraioli G, Tinelli C, Zicchetti M, Above E, Poma G, Di Gregorio M. Reproducibility of real-time shear wave elastography in the evaluation of liver elasticity. Europen Journal Radiology, 2012, 81: 3102–3106.

10. Friedrich-Rust M, Lupsor M de Knegt. Point Shear Wave Elastography by Acoustic Radiation Force Impulse Quantification in Comparison to Transient Elastography for the Noninvasive Assessment of Liver Fibrosis in Chronic Hepatitis C: A Prospective International Multi center Study. Ultraschall in Med, 2015, 36: 239-247.

11. Huang Z, Zheng J, Zeng J, Wang X, Wu T, Zheng R. Normal liver stiffness in healthy adults assessed by real-time Shear wave elastography and factors that infuence this method. Ultrasound Med Biology, 2014, 40: 2549–2555.

12. Liao LY, Kuo KL, Chiang HS, Lin CZ, Lin YP, Lin CL. Acoustic radiation force impulse elastography of the liver in healthy patients: test location, reference range and infuence of gender and body mass index. Ultrasound Med Biology, 2015, 41: 698-704.

13. Llop E, Berzigotti A, Reig M, Erice E, Reverter E, Seijo S et al. Assessment of portal hypertension by transient elastography in patients with compensated cirrhosis and potentially resectable liver tumors. Journal of Hepatology, 2012, 56: 103-108.

14. Nierhoff, J, Chavez Ortiz A., Herrmann E. The efficiency of acoustic radiation force impulse imaging for the staging of liver fibrosis: a meta-analysis. Europen Radiology, 2013, 23: 3040-3053.

15. Poynard T, Munteanu M, Luckina E, et al. Liver fibrosis evaluation using real-time shear wave elastography: applicability and diagnostic performance using methods without a gold standard. Journal of Hepatology, 2013, 5(85): 928–935.

16. Arena U, Vizzutti F, Abraldes JG et al. Reliability of transient elastography for the diagnosis of advanced fibrosis in chronic hepatitis C. Gut, 2008, 57(9): 1288-1293. doi: 10.1136/ gut.2008.149708. Epub 2008 Apr 30.

17. Zarski JP, Sturm N, Guechot J et al. Comparison of nine blood tests and transient elastography for liver fibrosis in chronic hepatitis C: the ANRS HCEP-23 study. J. Hepatol., 2012, 56(1): 55-62. doi: 10.1016/j.jhep.2011.05.024. Epub 2011 Jul 23.

18. Tang A, Cloutier G,Nikolaus M et al. Ultrasound Elastography and MR Elastography for Assessing Liver Fibrosis: Part 2, Diagnostic Performance, Confounders, and Future Directions. AJR Am J Roentgenol, 2015, 205(1): 33–40.

19. Kyu SJ, Seung UK. Clinical applications of transient elastography. Clin. Mol Hepatol., 2012, 18(2): 163–173. doi: 10.3350/ cmh.2012.18.2.163.

20. Jung KS, Kim SU, Ahn SH, Park YN, Kim DY et al. Risk assessment of hepatitis B virus-related hepatocellular carcinoma development using liver stiffness measurement (FibroScan). Hepatology (Baltimore, Md), 2011, 53: 885–894.

21. Павлов Ч.С. Резюме диссертаций: информация из ВАК России. Фиброз печени при хронических вирусных гепатитах В и С. Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2011, 21(6): 86-87.


Review

For citations:


Morozova TG, Borsukov AV, Bueverov AO. MULTIPARAMETRIC ELASTOGRAPHY – PRINCIPLES OF INDIVIDUAL SELECTION IN THE DIFFUSE LIVER DISEASES. Meditsinskiy sovet = Medical Council. 2017;(15):148-152. (In Russ.) https://doi.org/10.21518/2079-701X-2017-15-148-152

Views: 737


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2079-701X (Print)
ISSN 2658-5790 (Online)