ТАРГЕТНАЯ ТЕРАПИЯ БРЕНТУКСИМАБОМ ВЕДОТИНОМ ПРИ ЛЕЧЕНИИ РЕЦИДИВОВ И РЕФРАКТЕРНЫХ ФОРМ КЛАССИЧЕСКОЙ ЛИМФОМЫ ХОДЖКИНА
https://doi.org/10.21518/2079-701X-2017-14-88-92
Аннотация
Современные программы терапии первой линии позволяют излечить около 80% больных классической лимфомой Ходжкина при любой стадии заболевания, однако 10–30% больных оказываются рефрактерными и нуждаются в продолжении лечения. Стандартом лечения рецидивов или резистентных форм классической лимфомы Ходжкина является химиотерапия второй линии с высокодозной консолидацией под защитой аутологичных стволовых клеток крови, но эффективность такой терапии не превышает 50% для всей группы рефрактерных больных. Появление препаратов таргетного действия, специфичных для опухолевых клеток Березовского – Рид – Штернберга, открывает новые перспективы в лечении классической лимфомы Ходжкина. В статье приводится обзор исследований по применению нового таргетного препарата брентуксимаба ведотина при лечении рецидивов и рефрактерных форм классической лимфомы Ходжкина.
Об авторе
Е. А. Демина
Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина Минздрава России
Россия
Россия
Доктор медицинских наук, профессор.
Москва
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Рецензия
Для цитирования:
Демина Е.А. ТАРГЕТНАЯ ТЕРАПИЯ БРЕНТУКСИМАБОМ ВЕДОТИНОМ ПРИ ЛЕЧЕНИИ РЕЦИДИВОВ И РЕФРАКТЕРНЫХ ФОРМ КЛАССИЧЕСКОЙ ЛИМФОМЫ ХОДЖКИНА. Медицинский Совет. 2017;(14):88-92. https://doi.org/10.21518/2079-701X-2017-14-88-92
For citation:
Demina E.A. TARGETED THERAPY WITH BRENTUXIMAB VEDOTIN IN RELAPSED AND REFRACTORY FORMS OF CLASSICAL HODGKIN LYMPHOMA. Meditsinskiy sovet = Medical Council. 2017;(14):88-92. (In Russ.) https://doi.org/10.21518/2079-701X-2017-14-88-92
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