ПЕРСПЕКТИВЫ ПРИМЕНЕНИЯ СМЕСИ НА ОСНОВЕ КОЗЬЕГО МОЛОКА С БЕТА-ПАЛЬМИТИНОВОЙ КИСЛОТОЙ У ДЕТЕЙ ПЕРВОГО ГОДА ЖИЗНИ
https://doi.org/10.21518/2079-701X-2017-19-34-39
Аннотация
Грудное молоко является оптимальным питанием для ребенка первого года жизни. Состав и значение отдельных компонентов грудного молока раскрывается и изучается. Это позволяет совершенствовать современные детские молочные смеси для младенцев, которые по разным причинам не могут получать грудное вскармливание. Поскольку энергетические потребности ребенка на первом году жизни высоки и именно с жировой составляющей рациона он получает до 50% энергии, важна адаптация жирового компонента смеси, в частности, дополнение бета-пальмитиновой кислотой. Потребление младенцами смеси с бета-пальмитиновой кислотой способствует улучшению усвоения жира и кальция; повышению концентрации бифидо- и лактобактерий, формированию мягкого стула. Данные эффекты облегчают пищеварение, способствуют минерализации костной ткани, а также уменьшают продолжительность плача.
Ключевые слова
Об авторах
О. Н. Комарова
Научно-исследовательский клинический институт педиатрии им. акад. Ю.Е. Вельтищева Российского национального исследовательского медицинского университета им. Н.И. Пирогова
Россия
Россия
к.м.н.,
Москва
А. И. Хавкин
Научно-исследовательский клинический институт педиатрии им. акад. Ю.Е. Вельтищева Российского национального исследовательского медицинского университета им. Н.И. Пирогова
Россия
Россия
д.м.н., профессор,
Москва
Список литературы
1. Koletzko B, Agostini C, Bergmann R, Ritzen thaler K, Shamir R. Physiological aspects of human milk lipids and implications for infant feeding: a workshop report. Acta Paediatr, 2011, 100: 1405–15.
2. Haenlein GFH. Goat milk in human nutrition. Small Rumin Res., 2004, 51: 155–163.
3. Детское питание: Руководство для врачей. Под ред. В.А. Тутельяна, И.Я. Коня. М.: ООО «МИА», 2009. 952 с.
4. Jensen C, Buist NR and Wilson T. Absorption of individual fatty acids from long chain or medium chain triglycerides in very small infants. Am J Clin Nutr, 1986, 43(5): 745-51.
5. Small, D.M., The effects of glyceride structure on absorption and metabolism. Annu Rev Nutr, 1991, 11: 413-34.
6. Innis SM, Dyer R, Nelson CM. Evidence that palmitic acid is absorbed as sn-2 monoacylglycerol from human milk by breast-fed infants. Lipids, 1994, 29: 541–5.
7. Lopez-Lopez A, Castellote-Bargallo AI, CampoyFolgoso C, Rivero-Urgel M, Tormo-Carnice R, Infante-Pina D, Lopez-Sabater MC. The influence of dietary palmitic acid triglyceride position on the fatty acid, calcium and magnesium contents of at term new born faeces. Early Hum Dev, 2001, 65(Suppl): 83–94.
8. Straarup EM, Lauritzen L, Faerk J, Hoy CE, Michaelsen KF. The stereospecific triacylglycerol structure and fatty acid profiles of human milk and infant formulas. J Pediatr Gastroenterol Nutr, 2006, 42: 293–9.
9. Innis SM, Nelson CM. Dietary triacyglycerols rich in sn-2 palmitate alter post-prandial lipoprotein and unesterified fatty acids in term infants. Prostaglandins Leukot Essent Fatty Acids, 2013, 89: 145–51.
10. Nelson CM, Innis SM. Plasma lipoprotein fatty acids are altered by the positional distribution of fatty acids in infant formula triacylglycerols and human milk. Am J Clin Nutr, 1999, 70: 62–9.
11. Berry SE. Triacylglycerol structure and interesterification of palmitic and stearic acid-rich fats: an overview and implications for cardiovascular disease. Nutr Res Rev, 2009, 22: 3–17.
12. Birch EE et al. A randomized controlled trial of early dietary supply of long-chain polyunsaturated fatty acids and mental development in term infants. Developmental Medicine & Child Neurology, 2000, 42: 174–181.
13. Agostoni C et al. Neurodevelopmental quotient of healthy term infants at 4 months and feeding practice: the role of long-chain polyunsaturated fatty acids. Pediatr Res, 1995, 38: 262-266.
14. Hoffman DR et al. Toward optimizing vision and cognition in term infants by dietary docosahexaenoic and arachidonic acid supplementation: A review of randomized controlled trials. Prostaglandins, Leukotrienes and essential fatty acids, 2009, 81: 151-158.
15. Carnielli VP, Luijendik IHT, van Goudoever JB, Sulkers EJ, Boerla AA, Degenhart HJ, Sauer PJ. Structural position and amount of palmitic acid in formulas: effects on fat, fatty acid, and mineral balance. J Pediatr Gastroenterol Nutr, 1996, 23: 554–60.
16. Kennedy K, Fewtrell MS, Morley R, Abbott R, Quinlan PT, Wells JCK, Bindels JG. Double-blind, randomized trial of a synthetic triacylglycerol in formula-fed term infants: effects on stool biochemistry, stool characteristics, and bone mineralization. Am J Clin Nutr, 1997, 70: 920–7.
17. Nowacki J, Lee HC, Lien R, Cheng SW, Li ST, Yao M, Northington R, Jan I, Mutungi G. Stool fatty acid soaps, stool consistency and gastrointestinal tolerance in term infants fed infant formulas containing high sn-2 palmitate with or without oligofructose: a double-blind, randomized clinical trial. Nutr J, 2014, 13: 105.
18. Yao M, Lien EL, Capeding MR, Fitzgerald M, Ramanujam K, Yuhas R, Nortington R, Lebumfacil J, Wang L, DeRusso PA. Effects of term infant formulas containing high sn-2 palmitate with and without oligofructose on stool composition, stool characteristics, and bifidogenicity: a randomized, double-blind, controlled trial. J Pediatr Gastroenterol Nutr, 2014, 59: 440–8.
19. Juarez M, Ramos M. Physico-chemical characteristics of goat milk as distinct from those of cows milk. Int. Dairy Fed Buffl, 1986, 202: 54-67.
20. Bruzzese E et al. Early administration of Gos/ Fos prevents intestinal and respiratory infections in infants. J of Pediatric Gastroenterology & Nutrition, 2006, 42: E95.
21. AFSSA. Rapport du groupe de travail «Alimentation infantile et modification de la flore intestinale». Juin 2003.
22. Lee YS, Kang EY, Park MN, Choi YY, Jeon JW, Yun SS. Effectsof sn-2 palmitic acid-fortified vegetable oil and fructooligosaccharide on calcium metabolism in growing rats fed casein based diet. Nutr Res Pract, 2008, 2: 3–7.
23. Bar-Yoseph F, Lifshitz Z, Cohen T. Review of sn-2 palmitate oil implications for infant health. Prostaglandins Leukot Essent Fatty Acids, 2013, 4: 139–43.
24. Litmanovitz I, Davidson K, Eliakim A, Regev RH, Dolfin T, Arnon S, Bar-Yoseph F, Goren F, Goren A, Lifshitz Y, Nemet D. High-beta-palmitate formula and bone strength in term infants: a randomized, double-blind, controlled trial. Calcif Tissue Int, 2013, 92: 35–41.
25. Biedermann L, Rogler G. Environmental factors and their impact on the intestinal microbiota: a role for human disease? Dig Dis, 2009, 30(Suppl 3): 20–7.
26. Deveraj S, Hemarajata P, Versalovic J. The human gut microbiome and body metabolism: implications for obesity and diabetes. Clin Chem, 2013, 59: 617–28.
27. Douglas-Escobar M, Elliott E, Neu J. Effect of intestinal microbialecology on the developing brain. JAMA Pediatr, 2013, 167: 374–9.
28. Yaron S, Shachar D, Abramas L, Riskin A, Bader D, Litmanovitz I, Bar-Yoseph F, Cohen T, Levi L, Lifshitz Y, Shamir R. Shaoul. Effect of high β-palmitate content in infant formula on the intestinal microbiota of term infants. J Pediatr Gastroenterol Nutr, 2013, 56: 376–81.
29. Euler AR, Mitchell DK, Kline R, et al. Prebiotic effect of fructo-oligosaccharide supplemented term infant formula at two concentrations compared with unsupplemented formula and human milk. J Pediatr Gastroenterol Nutr, 2005, 40:157–164. [PubMed]
30. Kapiki A, Costalos C, Oikonomidou C, et al. The effect of a fructo-oligosaccharide supplemented formula on gut flora of preterm infants. Early Hum Dev, 2007, 83: 335–339.
31. Waligora-Dupriet AJ, Campeotto F, Nicolis I, et al. Effect of oligofructose supplementation on gut microflora and well-being in young children attending a day care centre. Int J Food Microbiol, 2007, 113: 108–113.
32. Lu P, Bar-Yoseph F, Levi L, Lifshitz Y, WitteBouma J, de Bruijn ACJM, Korteland-van Male AM, van Goudoever JB, Renes IB. High beta-palmitate fat controls the intestinal inflammatory response and limits intestinal damage in mucin Muc2 deficient mice. PLoS One, 2013, 8: e65878.
33. Savino F, Palumeri E, Castagno E, Cresi F, Dalmoso P, Cacallo F, Oggero R. Reduction of crying episodes owing to infantce colic: a randomized controlled study on the efficacy of a new infant formula. Eur J Clin Nutr, 2006, 60: 1304–10.
34. Litmanovitz I, Bar-Yoseph F, Lifshitz Y, Davidson K, Eliakim A, Regev RH, Nemet D. Reduced crying in term infants fed high beta-palmitate formula: a double-blind randomized clinical trial. BMC Pediatr, 2014, 14: 152.
35. Vaughn LK, Denning G, Stuhr KL, de Wit H, Hill MN, Hillard CJ. Endocannabinoid signalling: has it got rhythm? Br. J. Pharmacol., 2010, 160(3): 530–543.
36. Newman JD. Neural circuits underlying crying and cry responding in mammals, Behav. Brain Res., 2007, 182(2): 155-165.
37. Banni S, Carta G, Murru E et al. In: Proceedings of ISSFAL, Vancouver, Canada, 2012. In: Proceedings of ISSFAL, Vancouver, Canada, 2012.
Рецензия
Для цитирования:
Комарова ОН, Хавкин АИ. ПЕРСПЕКТИВЫ ПРИМЕНЕНИЯ СМЕСИ НА ОСНОВЕ КОЗЬЕГО МОЛОКА С БЕТА-ПАЛЬМИТИНОВОЙ КИСЛОТОЙ У ДЕТЕЙ ПЕРВОГО ГОДА ЖИЗНИ. Медицинский Совет. 2017;(19):34-39. https://doi.org/10.21518/2079-701X-2017-19-34-39
For citation:
Komarova ON, Khavkin AI. PROSPECTS OF APPLICATION OF A MIXTURE BASED ON GOAT MILK WITH BETA-PALMITIC ACID IN CHILDREN THE FIRST YEAR OF LIFE. Meditsinskiy sovet = Medical Council. 2017;(19):34-39. (In Russ.) https://doi.org/10.21518/2079-701X-2017-19-34-39
Просмотров:
704
Послать статью по эл. почте 