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ROLE OF VITAMIN D IN REGULATION OF IMMUNITY, PREVENTION AND THERAPY OF INFECTIOUS PEDIATRIC DISEASES

https://doi.org/10.21518/2079-701X-2017-19-52-60

Abstract

Children with vitamin D insufficiency are characterized by antiviral and antibacterial immunity. And, contrariwise, supplements of vitamin D have immunomodulating and anti-inflammatory action, and protect the child body from infection. The data of the evidence-based medicine testify the importance of the use of vitamin D to prevent and to treat tuberculosis, chronic bronchitis, prevention of respiratory tracts infections, including those caused by RSV (respiratory and syncitial virus) and Group A virus.

About the Authors

O. A. Gromova
Ivanovo State Medical Academy of the Ministry of Health of Russia; Federal Research Center IT Studies and Management of RAS (Institute of Modern Information Technologies in Medicine)
Russian Federation

MD, Prof., 

Moscow



I. Y. Torshin
Federal Research Center IT Studies and Management of RAS (Institute of Modern Information Technologies in Medicine)
Russian Federation

PhD in Pharmacy and Medicine,

Moscow



I. N. Zakharova
Russian Medical Academy of Continuous Professional Education of the Ministry of Health of Russia
Russian Federation

MD, Prof.,

Moscow



S. I. Malyavskaya
North-Western State Medical University of the Ministry of Health of Russia
Russian Federation

MD, Prof.,

Arkhangelsk



References

1. Громова О.А., Торшин И.Ю. Витамин D – смена парадигмы. М., ГЭОТАР-Медиа, 2017, ISBN: 978-5-9704-4058-2, 568 с.

2. Balcells ME, García P, Tiznado C, Villarroel L, Scioscia N, Carvajal C, Zegna-Ratá F, Hernández M, Meza P, González LF, Peña C, Naves R. Association of vitamin D deficiency, season of the year, and latent tuberculosis infection among household contacts. PLoS One, 2017 Apr 12, 12(4): e0175400. doi: 10.1371/journal. pone.0175400.

3. Agrawal N, Bhattacharyya C, Mukherjee A, Ullah U, Pandit B, Rao KV, Majumder PP. Dissecting host factors that regulate the early stages of tuberculosis infection. Tuberculosis (Edinb), 2016 Sep, 100: 102-13. doi: 10.1016/j. tube.2016.07.009.

4. Schrumpf JA, Amatngalim GD, Veldkamp JB, Verhoosel RM, Ninaber DK, Ordonez SR, van der Does AM, Haagsman HP, Hiemstra PS. Proinflammatory Cytokines Impair Vitamin D-induced Host Defense in Cultured Airway Epithelial Cells. Am J Respir Cell Mol Biol, 2017 Feb 23. doi: 10.1165/rcmb.2016-0289OC.

5. Aryan Z, Rezaei N, Camargo CA Jr. Vitamin D status, aeroallergen sensitization, and allergic rhinitis: A systematic review and meta-analysis. Int Rev Immunol, 2017 Jan 2, 36(1): 41-53. doi: 10.1080/08830185.2016.1272600. Epub 2017 Jan 19.

6. Sundaram ME, Coleman LA. Vitamin D and influenza. Adv Nutr, 2012, 3(4): 517-25. doi: 10.3945/an.112.002162.

7. Громова О.А., Калачева А.Г., Торшин И.Ю., Рудаков К.В. и др. Недостаточность магния - достоверный фактор риска коморбидных состояний: результаты крупномасштабного скрининга магниевого статуса в регионах России. Фарматека, 2013, 6(259): 115-129.

8. Torshin IYu, Rudakov KV. Combinatorial analysis of the solvability properties of the problems of recognition and completeness of algorithmic models. Part 1: Factorization approach. Pattern Recognition and Image Analysis, 2017, 27(1): 16–28. DOI: 10.1134/S1054661817010151.

9. Torshin IYu, Rudakov KV. On metric spaces arising during formalization of problems of recognition and classification. Part 2: Density properties. Pattern Recognition and Image Analysis, 2016, 26(3): 483-496. DOI: 10.1134/ S1054661816030202.

10. Khoo AL, Chai LY. Vitamin D(3) down-regulates proinflammatory cytokine response to Mycobacterium tuberculosis through pattern recognition receptors while inducing protective cathelicidin production. Cytokin, 2011, 55(2): 294-300.

11. Lang PO, Samaras D. Aging adults and seasonal influenza: does the vitamin d status (h)arm the body? J Aging Res, 2012, 2012: 806198.

12. Korucu E, Pur Ozyigit L, Ortakoylu MG, Bahadir A, Akalin ES, Kara A, Uzun H, Onal B, Caglar E. Cathelicidin as a link between sarcoidosis and tuberculosis. Sarcoidosis Vasc Diffuse Lung Dis, 2015 Sep 14, 32(3): 222-7.

13. Stagi S, Bertini F. Vitamin D levels and effects of vitamin D replacement in children with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome. Int J Pediatr Otorhinolaryngol, 2014, 78(6): 964-8.

14. Amaya-Mejia AS, O’Farrill-Romanillos PM, Galindo-Pacheco LV, Vargas-Ortega G, MendozaZubieta V, Del Rivero-Hernandez LG, SeguraMendez NH. [Vitamin D deficiency in patients with common variable immunodeficiency, with autoimmune diseases and bronchiectasis]. Rev Alerg Mex, 2013, 60(3): 110-116.

15. Riverin BD, Maguire JL, Li P. Vitamin D Supplementation for Childhood Asthma: A Systematic Review and Meta-Analysis. PLoS One, 2015, 10(8): e0136841 doi.

16. Man L, Zhang Z, Zhang M, Zhang Y, Li J, Zheng N, Cao Y, Chi M, Chao Y, Huang Q, Song C, Xu B. Association between vitamin D deficiency and insufficiency and the risk of childhood asthma: evidence from a meta-analysis. Int J Clin Exp Med, 2015, 8(4): 5699-706 eCollectio.

17. Feng H, Xun P, Pike K, Wills AK, Chawes BL, Bisgaard H, Cai W, Wan Y, He K. In utero exposure to 25-hydroxyvitamin D and risk of childhood asthma, wheeze, and respiratory tract infections: A meta-analysis of birth cohort studies. J Allergy Clin Immunol, 2016, J Allergy: S0091-6749(16)3096.

18. Kim YH, Kim KW, Kim MJ, Sol IS, Yoon SH, Ahn HS, Kim HJ, Sohn MH, Kim KE. Vitamin D levels in allergic rhinitis: a systematic review and meta-analysis. Pediatr Allergy Immunol, 2016, 27(6): 580-90 doi.

19. Song H, Yang L, Jia C. Maternal vitamin D status during pregnancy and risk of childhood asthma: A meta-analysis of prospective studies. Mol Nutr Food Res, 2016, Mol Nutr F: 101002/ mnfr20160065.

20. Aryan Z, Rezaei N, Camargo CA Jr. Vitamin D status, aeroallergen sensitization, and allergic rhinitis: A systematic review and meta-analysis. Int Rev Immunol, 2017, 36(1): 41-53.

21. Selvaraj P. Vitamin D, vitamin D receptor, and cathelicidin in the treatment of tuberculosis. Vitam Horm, 2011, 86: 307-25.

22. Neme A, Nurminen V, Seuter S, Carlberg C. The vitamin D-dependent transcriptome of human monocytes. J Steroid Biochem Mol Biol, 2016 Nov, 164: 180-187. doi: 10.1016/j. jsbmb.2015.10.018.

23. Verway M. Vitamin D induces interleukin-1beta expression: paracrine macrophage epithelial signaling controls M. tuberculosis infection. PLoS Pathog, 2013, 9(6): e1003407.

24. Iftikhar R, Kamran SM. Vitamin D deficiency in patients with tuberculosis. J Coll Physicians Surg Pak, 2013, 23(10): 780-3.

25. Kibirige D, Mutebi E. Vitamin D deficiency among adult patients with tuberculosis: a cross sectional study from a national referral hospital in Uganda. BMC Res Notes, 2013, 6(1): 293. 26. Desai NS, Tukvadze N. Effects of sunlight and diet on vitamin D status of pulmonary tuberculosis patients in Tbilisi, Georgia. Nutrition, 2012, 28(4): 362-6.

26. Nnoaham KE, Clarke A. Low serum vitamin D levels and tuberculosis: a systematic review and meta-analysis. Int J Epidemiol, 2008, 37(1): 113-9.

27. Coussens AK, Wilkinson RJ, Hanifa Y, Nikolayevskyy V, Elkington PT, Islam K, Timms PM, Venton TR. Vitamin D accelerates resolution of inflammatory responses during tuberculosis treatment. Proc Natl Acad Sci U S A, 2012, 109(38): 15449-54.

28. Ganmaa D, Giovannucci E, Bloom BR, Fawzi W, Burr W, Batbaatar D, Sumberzul N, Holick MF, Willett WC. Vitamin D, tuberculin skin test conversion, and latent tuberculosis in Mongolian school-age children: a randomized, doubleblind, placebo-controlled feasibility trial. Am J Clin Nutr, 2012, 96(2): 391-6.

29. Lange CM, Bojunga J, Ramos-Lopez E. Vitamin D deficiency and a CYP27B1-1260 promoter polymorphism are associated with chronic hepatitis C and poor response to interferonalfa based therapy. J Hepatol, 2011, 54(5): 887-9.

30. Villar LM. Association between vitamin D and hepatitis C virus infection: a meta-analysis. World J Gastroenterol, 2013, 19(35): 5917-24.

31. Petta S, Camma C. Low vitamin D serum level is related to severe fibrosis and low responsiveness to interferon-based therapy in genotype 1 chronic hepatitis C. Hepatology, 2010, 51(4): 1158-67.

32. Bitetto D, Fabris C. Vitamin D supplementation improves response to antiviral treatment for recurrent hepatitis C. Transpl Int, 2011, 24(1): 43-50.

33. Zhuravskaia EL. Effect of rickets prevention on bronchopneumonia morbidity and mortality in children during the 1st vear of life in rural areas. Pediatr Akus Ginekol, 1962, 5: 32-3.

34. Salimpour R. Rickets in Tehran. Study of 200 cases. Arch Dis Child, 1975 Jan, 50(1): 63-6.

35. Muhe L, Lulseged S. Case-control study of the role of nutritional rickets in the risk of developing pneumonia in Ethiopian children. Lancet, 1997 Jun 21, 349(9068): 1801-4.

36. Захарова И.Н., Мальцев С.В., Боровик Т.Э., Яцык Г.В., Малявская С.И., Вахлова И.В., Шуматова Т.А., Романцова Е.Б., Романюк Ф.П., Климов Л.Я., Елкина Т.Н., Пирожкова Н.И., Колесникова С.М., Курьянинова В.А., Васильева С.В., Мозжухина М.В., Евсеева Е.А.. Недостаточность витамина d у детей раннего возраста в России (результаты многоцентрового исследования – зима 2013–2014 гг.). Вопросы фармакоэпидемиологии, 2014: 75-80.

37. Charan J, Goyal JP, Saxena D, Yadav P. Vitamin D for prevention of respiratory tract infections: A systematic review and meta-analysis. J Pharmacol Pharmacother, 2012, 3(4): 300-3.

38. Khare D, Godbole NM, Pawar SD [1, 25[OH]2 D3] pre- and post-treatment suppresses inflammatory response to influenza A (H1N1) infection in human lung A549 epithelial cells. Eur J Nutr, 2013, 52(4): 1405-15.

39. Santini F. Human respiratory syncytial virus and Th1 chemokines. Clin Ter, 2015, 166(3): e203-8. doi: 10.7417/T.2015.1855.

40. Bergman P, Lindh AU. Vitamin D and Respiratory Tract Infections: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. PLoS One, 2013, 8(6): e65835.

41. Jat KR. Vitamin D deficiency and lower respiratory tract infections in children: a systematic review and meta-analysis of observational studies. Trop Doct, 2017 Jan, 47(1): 77-84.

42. Christensen N, Søndergaard J, Fisker N, Christesen HT. Infant Respiratory Tract Infections or Wheeze and Maternal Vitamin D in Pregnancy. Pediatr Infect Dis J, 2017 Apr, 36(4): 384-391. doi: 10.1097/INF.0000000000001452.

43. Herscovitch K, Dauletbaev N, Lands LC. Vitamin D as an anti-microbial and anti-inflammatory therapy for Cystic Fibrosis. Paediatr Respir Rev, 2014, 15(2): 154-62.

44. Громова О.А., Торшин И.Ю., Захарова И.Н., Спиричев В.Б., Лиманова О.А., Боровик Т.Э., Яцык Г.В. О дозировании витамина D у детей и подростков. Вопросы современной педиатрии, 2015, 14(1): 38-47. DOI: 10.15690/vsp. v14i1.1261


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For citations:


Gromova OA, Torshin IY, Zakharova IN, Malyavskaya SI. ROLE OF VITAMIN D IN REGULATION OF IMMUNITY, PREVENTION AND THERAPY OF INFECTIOUS PEDIATRIC DISEASES. Meditsinskiy sovet = Medical Council. 2017;(19):52-60. (In Russ.) https://doi.org/10.21518/2079-701X-2017-19-52-60

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