Побочные эффекты адъювантной гормонотерапии
https://doi.org/10.21518/2079-701X-2018-10-64-69
Аннотация
Гормонотерапия является высокоэффективным и в целом хорошо переносимым методом лечения гормонозависимого рака молочной железы. Тем не менее существует ряд побочных эффектов, которые могут снижать качество жизни пациенток и являться причиной преждевременной отмены препаратов. В статье обсуждаются основные нежелательные явления гормонотерапии: менопаузальные симптомы, гинекологические эффекты тамоксифена, сердечно-сосудистые, скелетно-мышечные осложнения. Некоторые из них могут быть предотвращены или скорректированы. Для сохранения удовлетворительного качества жизни пациенток следует больше внимания уделять побочным эффектам, действительно его снижающим, и не проявлять избыточной активности по поводу клинически незначащих проявлений.
Об авторах
E. И. Коваленко
ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава России
Россия
Россия
Кандидат медицинских наук
И. Б. Кононенко
ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава России
Россия
Россия
Кандидат медицинских наук
А. В. Снеговой
ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава России
Россия
Доктор медицинских наук
Россия
Доктор медицинских наук
О. П. Гребенникова
ФГБОУ ВО «Московский государственный медико-стоматологический университет им. А.И. Евдокимова» Минздрава России
Россия
Россия
Кандидат медицинских наук
Л. В. Манзюк
ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава России
Россия
Доктор медицинских наук, профессор
Россия
Доктор медицинских наук, профессор
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Рецензия
Для цитирования:
Коваленко EИ, Кононенко ИБ, Снеговой АВ, Гребенникова ОП, Манзюк ЛВ. Побочные эффекты адъювантной гормонотерапии. Медицинский Совет. 2018;(10):64-69. https://doi.org/10.21518/2079-701X-2018-10-64-69
For citation:
Kovalenko EI, Kononenko IB, Snegovoi AV, Grebennikova OP, Manzyuk LV. Adverse effects of adjuvant endocrine therapy. Meditsinskiy sovet = Medical Council. 2018;(10):64-69. (In Russ.) https://doi.org/10.21518/2079-701X-2018-10-64-69
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