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Тяжелая эозинофильная бронхиальная астма: новые возможности терапии

https://doi.org/10.21518/2079-701X-2018-15-44-52

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Аннотация

Эозинофильная астма является распространенным фенотипом тяжелой астмы и встречается по крайней мере у половины пациентов. За последнее время произошли существенные изменения в подходах к лечению тяжелой бронхиальной астмы, и прежде всего эозинофильной астмы. В статье обсуждаются вопросы роли эозинофилов в патогенезе тяжелой астмы, выявления фенотипа тяжелой эозинофильной астмы и современные подходы к таргетной терапии тяжелой астмы эозинофильного фенотипа с помощью биологических препаратов. Особый акцент сделан на препараты моноклональных антител к интерлейкину-5, в частности меполизумаб, недавно одобренный для клинического применения в нашей стране.

Об авторе

Н. А. Ненашева
ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России
Россия

Ненашева Наталья Михайловна – доктор медицинских наук, профессор кафедры клинической аллергологии.

Москва



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ISSN 2079-701X (Print)
ISSN 2658-5790 (Online)