Роль нейротропных витаминов группы B в клинической практике

Витамины группы B представляют собой группу из 8 водорастворимых витаминов. Они являются кофакторами для многих ферментов, а также аксонального транспорта, синтеза нейротрансмиттеров и других метаболических процессов. Их функцию можно разделить на катаболический метаболизм, приводящий к выработке энергии, и анаболический метаболизм. Некоторые витамины группы B считаются нейротропными и играют особую важную роль как в центральной, так и в периферической нервной системе. Нейротропные витамины группы В (В₁ – тиамин, В₆ – пиридоксин и В₁₂ – цианокобаламин) играют роль модуляторов воспаления и боли, они необходимы для правильного функционирования нервной системы. Дефицит этих витаминов рассматривается как этиологический фактор развития различных неврологических расстройств и широкого спектра патологических состояний. В работе подробно рассмотрены витамины В₁, В₆ и В₁₂ и их влияние на течение невропатий, двигательных нарушений, ноцицептивной и невропатической боли. Освещены вопросы синергического действия этих витаминов. Представлены данные эффективности лечения нейротропными витаминами группы B симптомов невропатии у разных групп пациентов. Рассмотрена  возможность  использования  комплекса  витаминов В₁ и В₆ в клинической практике при условии непереносимости витамина В₁₂. Представлены сведения о препарате Цитипигам® композитум как содержащем витамины В₁ и В₆. Описан клинический случай эффективного применения указанного препарата в клинической практике.

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