Обоснование к экзогенному восполнению дефицита магния у женщин, планирующих беременность: опыт применения

Введение. Во время беременности увеличивается потребность организма в большинстве микронутриентов, в связи с чем обоснованы своевременное выявление и адекватная коррекция дефицитных состояний, начиная с этапа прегравидарной подготовки.

Цель. Представить данные литературы о роли магния в гомеостазе и собственный опыт эффективности применения препарата магния.

Материалы и методы. Проведен обзор литературы за 2018–2023 гг. в базах PubMed (the National Library of Medicine), The Cochrane Library, а также в базах данных научного цитирования (Scopus, Web of Science). Также представлен опыт собственного применения препарата, содержащего магния лактата дигидрат (470 мг) + пиридоксина гидрохлорид (5 мг).

Результаты и обсуждение. Поступление магния в организм человека с пищей является недостаточным. Экзогенное восполнение магния клинически обоснованно при изолированном или связанном с другими состояниями установленном дефиците, в первую очередь при интенсивной эмоциональной и физической нагрузке, депривации сна, а также при эмоциональной лабильности, ощущениях учащенного сердцебиения, фасцикуляции мышц, элиминации магния, обусловленной ятрогенным воздействием или повышенным запросом, например гестационно обусловленным. Регулярное применение препарата «Магне В6®» продемонстрировало свою эффективность при лечении симптомов психологического ежедневного стресса (утомляемость, раздражительность, ухудшение качества сна) у женщин, планирующих беременность.

Заключение. Полученные результаты представляются важными с позиции снижения рисков клинического прогрессирования соматических проявлений, а также снижения рисков потенциальных гестационных осложнений и улучшения качества жизни у женщин детородного возраста, активно планирующих реализацию репродуктивной функции.

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