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Outcome prediction in children with cancer and hematological diseases that are in the intensive care unit, based on laboratory indicators

https://doi.org/10.21518/2079-701X-2016-07-128-131

Abstract

In order to predict the outcomes of care of children with cancer and hematological diseases in the intensive care unit (ICU) were studied in dynamics for 7 days before the end of stay in the ICU performance of laboratory tests in 45 children with poor and 38 children with a favorable outcome. Children with poor outcome revealed violations of the acid-base balance, haematological, hepatic and renal dysfunction. Identify a set of informative laboratory indices to predict the outcome in children with cancer and hematological diseases. The sensitivity of the combined laboratory parameters measured during the last 7 days of stay in the ICU, was 89% (81–94%), specificity of 97% (92–99%).

About the Authors

W. M. Delyagin
Federal Scientific and Clinical Centre of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev
Russian Federation
MD, professor


S. Olimpieva
Federal Scientific and Clinical Centre of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev
Russian Federation
PhD


W. Kilikovski
Federal Scientific and Clinical Centre of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev
Russian Federation
PhD


A. Akostelova
Federal Scientific and Clinical Centre of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev
Russian Federation


I. Hamin
Federal Scientific and Clinical Centre of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev
Russian Federation
PhD


References

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3. Забродина Л.А., Альфонсова Е.В. Нарушения кислотно-щелочного равновесия и системы гемостаза у больных с острой тяжелой черепно-мозговой травмой. Современные проблемы науки и образования: электронный научный журнал. 2013. 2 (46). URL: http://www.science-education.ru/pdf/2013/2/423.pdf (дата обращения: 27.04.2015) // Zabrodina L.A., Al’fonsova E.W. Disturbances of acid-base balance and the system of hemostasis in patients with acute severe traumatic brain injury. Modern problems of science and education: electronic scientific journal. (in Russian) 2013. 2 (46). URL: http://www.science-education.ru/pdf/2013/2/423.pdf (date of the application: 27.04.2015).


Review

For citations:


Delyagin WM, Olimpieva S, Kilikovski W, Akostelova A, Hamin I. Outcome prediction in children with cancer and hematological diseases that are in the intensive care unit, based on laboratory indicators. Meditsinskiy sovet = Medical Council. 2016;(7):128-131. (In Russ.) https://doi.org/10.21518/2079-701X-2016-07-128-131

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ISSN 2079-701X (Print)
ISSN 2658-5790 (Online)