Drug correction of intestinal dyskinesias
https://doi.org/10.21518/2079-701X-2016-14-96-99
Abstract
Selective myotropic spasmolytics are the most effective modern correction means for pain at irritable bowel syndrome. Currently various drugs of mebeverine hydrochloride are represented in the domestic market, the dosage of the active substance in which is identical but they are produced by various technologies. We established that in patients with the irritable bowel syndrome administration of the drug Niaspam (Sun Pharmaceutical Industries Ltd.) at standard dosages for 2 weeks showed high effectiveness in arresting pain syndrome and intestinal dyskinesias. Niaspam statistically reliably reduces the relative intensity of intestinal contractions, normalizes the contraction rythmicity but effective predominantly in lower parts of the gastrointestinal tract. Peculiarities of the production technology allow gradual mebeverine release from the capsule, which is extremely important in therapy of intestinal dyskinesias.
About the Authors
M. A. Butov
SBEI HPE Pavlov Ryazan State Medical University of the Ministry of Health of the Russian Federation
Russian Federation
MD, Prof.
Russian Federation
MD, Prof.
E. M. Shurpo
SBEI HPE Pavlov Ryazan State Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
P. S. Kuznetsov
SBEI HPE Pavlov Ryazan State Medical University of the Ministry of Health of the Russian Federation
Russian Federation
PhD in medicine
Russian Federation
PhD in medicine
I. A. Zagravskaya
SBEI HPE Pavlov Ryazan State Medical University of the Ministry of Health of the Russian Federation
Russian Federation
PhD
Russian Federation
PhD
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Review
For citations:
Butov MA, Shurpo EM, Kuznetsov PS, Zagravskaya IA. Drug correction of intestinal dyskinesias. Meditsinskiy sovet = Medical Council. 2016;(14):96-99. (In Russ.) https://doi.org/10.21518/2079-701X-2016-14-96-99
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