Non-steroid antiinflammatory drugs in therapy of chronic abacterial prostatitis/syndrome of chronic pelvic pain
https://doi.org/10.21518/2079-701X-2016-17-133-137
Abstract
The inflammatory chronic abacterial prostatis/chronic pelvic pain syndrome accounts for 60-65% of all cases of chronic prostatitis. The etiology of the chronic abacterial prostatis/chronic pelvic pain syndrome remains unstudied to the full. The major objective of clinical study is to rule out possible organic urologic diseases. The inflammatory chronic abacterial prostatis/ chronic pelvic pain syndrome is characterized by the inflammatory reaction in the prostate secretion in absence of bacteria in the diagnostics titer in the urine and the prostate secretion. Cyclogenase-2 inhibitors reduce the content of prostaglandins in the sperm and urine, pain sensation and edema of the prostate gland. Use of nimesulide in patients of this category allows removing pelvic pains, increasing blood flow in the prostate gland at low percentage of adverse events.
About the Authors
A. D. KaprinRussian Federation
MD, Prof., RAS Corresponding Member
A. A. Kostin
Russian Federation
MD, Prof.
S. V. Popov
Russian Federation
PhD in medicine
References
1. Интегративная урология. Под ред. Глыбочко П.В., Аляева Ю.Г. М.: Медфорум, 2014. 432 с.
2. Ткачук В.Н. Хронический простатит. М.: МДВ, 2006. 112 с.
3. Комяков Б.К., Назаров Т.Х., Ризоев Х.Х. Хронический обструктивный простатит. СПб.: Русская коллекция, 2016. 111 с.
4. Richard G., Batstone D., Doble A. Chronic prostatitis. Curr Opin Urol, 2003, 13: 23-29.
5. Каратеев А.Е., Яхно Н.Н., Лазебник Л.Б., Кукушкин М.Л., Дроздов В.Н., Исаков В.А., Насонов Е.Л. Применение нестероидных противовоспа- лительных препаратов. М.: ИМА-ПРЕСС, 2009. 168 с.
6. Hochreiter WW. Anti-Inflammatory Therapies for Chronic Prostatitis. Curr Opin Urol, 2003, 2: 30-33.
7. Canale D, Scaricabarozzi I, Giorni P. Use of a novel non-steroid antiinflammatory drug, nimesulide, in the treatment of abacterial prostatovesiculitis. Andrologia, 1993, 25: 163-166.
8. Неймарк А.И., Яковец Я.В., Алиев Р.Т. Опыт использования найза (нимесулид) в комплексном лечении больных хроническим абактериальным простатитом с синдромом хронической тазовой боли. Урология, 2004, 5: 31-34.
9. Nickel JC, Downey J, Johnston B et al. Predictors of patient response to antibiotic therapy for the chronic prostatitis/chronic pelvic pain syndrome: a prospective multicenter clinical trial. J. Urol., 2001, 165: 1539-1544.
Review
For citations:
Kaprin AD, Kostin AA, Popov SV. Non-steroid antiinflammatory drugs in therapy of chronic abacterial prostatitis/syndrome of chronic pelvic pain. Meditsinskiy sovet = Medical Council. 2016;(17):133-137. (In Russ.) https://doi.org/10.21518/2079-701X-2016-17-133-137