Preview

Meditsinskiy sovet = Medical Council

Advanced search

TRENDS OF INITIAL METABOLIC SYNDROME AND ITS RELATIONSHIP WITH SUBCLINICAL ATHEROSCLEROSIS AMONG YOUNG AND MIDDLE-AGED MEN

https://doi.org/10.21518/2079-701X-2017-3-104-108

Abstract

Atherosclerotic cardiovascular diseases substantially have contributing to mortality and structure of disability in developed countries. Metabolic syndrome is a cluster of clinico-biochemical changes with the most aterogenic potential.

Objective: to determine trends of early stages of metabolic syndrome and its relationship with the initial atherosclerosis in young and middle-aged men. Have been examined 436 men with an assessment symptoms of metabolic syndrome, as well as signs of subclinical atherosclerosis. The young men with initial manifestations of metabolic syndrome were characterized by the classical cardiovascular risk factors. According to the results of the study have been already diagnosed dyslipidemia, violation of apolipoproteides fractions, postprandial hyperglycemia at the initial stage of metabolic syndrome in this category of patients. have been proposed assessment of waist circumference, degree of diastolic blood pressure and postprandial glycemia as the most sensitive diagnostic markers of cardiovascular lesions in primary manifestations of metabolic syndrome.

About the Authors

D. Y. Serdyukov
Military medical Academy. S. M. Kirov
Russian Federation
Saint-Petersburg


A. V. Gordienko
Military medical Academy. S. M. Kirov
Russian Federation
Saint-Petersburg


V. T. Dyidyishko
Military medical Academy. S. M. Kirov
Russian Federation
Saint-Petersburg


M. A. Panova
Military medical Academy. S. M. Kirov
Russian Federation
Saint-Petersburg


I. V. Rudchenko
Military medical Academy. S. M. Kirov
Russian Federation
Saint-Petersburg


References

1. Демографический ежегодник России. 2015. Стат. сб. Росстат. М., 2015. 264.

2. Global atlas on cardiovascular disease prevention and control. Policies, strategies and interventions. World Health Organization; World Stroke Organization. 2011.

3. Bianchi C, Miccoli R, Trombetta M et al. Elevated 1-hour postload plasma glucose levels identify subjects with normal glucose tolerance but impaired β-cell function, insulin resistance, and worse cardiovascular risk profile: the GENFIEV study. J. Clin. Endocrinol. Metab., 2013, 98(5): 2100-5.

4. Sciacqua A, Maio R, Miceli Sofia, Pascale A et al. Association between one-hour post-load plasma glucose levels and vascular stiffness in essential hypertension. PLOS One, 2012, 7(9): 115-22.

5. Srikanthan K, Feyh A, Visweshwar H, Shapiro JI, Sodhi K. Systematic review of metabolic syndrome biomarkers: a panel for early detection, management, and risk stratification in the west virginian population. Int. J. Med. Sci., 2016, 132016, 13(1): 25-38.

6. Ghantous CM, Azrak Z, Hanache S, Abou-Kheir W, Zeidan A. Differential role of leptin and adiponectin in cardiovascular system. International Journal of Endocrinology, 2015: 1-13.

7. Дедов И.И., Шестакова М.В. Инретины: новая веха в лечении сахарного диабета 2-го типа. Практическое руководство для врачей. М.: Дипак, 2010. 92 с.

8. Gibbons C, Caudwell P, Finlayson G, Webb D-L, Hellström PM, Näslund E et al. Comparison of postprandial profiles of ghrelin, active GLP-1, and total PYY to meals varying in fat and carbohydrate and their association with hunger and the phases of satiety. J Clin Endocrinol Metab, 2013, 98(5): E847-E85.

9. Рекомендации экспертов Российского кардиологического общества по диагностике и лечению метаболического синдрома. 3-й пересмотр, М. 2013.

10. Барсуков А.В. Гипертоническое сердце в терапевтической практике. СПб.: ЭЛБИ-СПб, 2016: 384.

11. Драпкина О.М, Гацолаева Д.С., Ивашкин В.Т. Неалкогольная жировая болезнь печени как компонент метаболического синдрома. Российские медицинские вести, 2010, 2: 72-8.

12. IDF Consensus Worldwide Definition of the Metabolic Syndrome. International Diabetes Federation, Brussels, Belgium. 2006: 24.

13. Бацков С.С., Пронина Г.А., Инжеваткин Д.И. Неалкогольная жировая болезнь поджелудочной железы как дигестивный маркер метаболического синдрома. Медико-биологические и социально-психологические проблемы безопасности в чрезвычайных ситуациях, 2012, 4: 50-5.


Review

For citations:


Serdyukov DY, Gordienko AV, Dyidyishko VT, Panova MA, Rudchenko IV. TRENDS OF INITIAL METABOLIC SYNDROME AND ITS RELATIONSHIP WITH SUBCLINICAL ATHEROSCLEROSIS AMONG YOUNG AND MIDDLE-AGED MEN. Meditsinskiy sovet = Medical Council. 2017;(3):104-108. (In Russ.) https://doi.org/10.21518/2079-701X-2017-3-104-108

Views: 684


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2079-701X (Print)
ISSN 2658-5790 (Online)