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BILIARY SLUDGE AS THE INITIAL STAGE OF CHOLELITHIASIS. THERAPY AND PREVENTION

https://doi.org/10.21518/2079-701X-2017-5-65-69

Abstract

The results of domestic epidemiological studies on the prevalence of gallstone disease (GSD) indicate that it amounts to 10–15% of the adult population. The frequency increases in young adults and even in children [1]. The effectiveness of conservative therapy, despite certain achievements in this area remains low. Analysis of the results of treatment with ursodeoxycholic acid (UDCA) in patients with GSD showed that complete dissolution of stones in different periods occurred in 77 of 210 patients (36%) and dissolution in part – in 55 (26%) [2]. According to our data, dissolution of small (<5 mm) stones is more effective (71,5%) [5]. In general, the causes of the low efficiency lies in the long duration of treatment, its high costs and relatively low compliance of patients.

About the Authors

O. N. Minushkin
FGBU DPO CGMA of the President Affairs Administration of the RF
Russian Federation

MD, Prof.



L. V. Maslovsky
FGBU DPO CGMA of the President Affairs Administration of the RF
Russian Federation

MD



O. A. Eremenko
FGBU DPO CGMA of the President Affairs Administration of the RF
Russian Federation


O. F. Shaposhnikova
FGBU DPO CGMA of the President Affairs Administration of the RF
Russian Federation


M. S. Makarova
FGBU DPO CGMA of the President Affairs Administration of the RF
Russian Federation


References

1. Ильченко А.А. Желчнокаменная болезнь. М.: Анахарсис, 2004, 200 с.

2. Ильченко А.А. Современный взгляд на проблему билиарного сладжа. РМЖ. Болезни органов пищеварения, 2010, 28: 1707-1713.

3. Ильченко А.А. Классификация желчнокаменной болезни. Тер. архив, 2004, 2: 75-79.

4. Масловский Л.В., Бурдина Е.Г., Хохлова С.Ю., Шапошникова О.Ф., Минушкин О.Н. Профилактика желчнокаменной болезни: решенные и нерешенные вопросы. Кремлевская медицина, 1998, 2: 19-22

5. Минушкин О.Н. Препараты урсодезоксихолевой кислоты в клинической практике (методическое пособие, издание 2-е, дополненное). М., 2016, 44 с.

6. Саблин О.А., Ильчишина Т.А., Ледовская А.А. Заболевания желчного пузыря. Возможности терапии препаратами урсодезоксихолевой кислоты. Методическое пособие. СПб.: Абсолют Н, 2013. 34 с.


Review

For citations:


Minushkin ON, Maslovsky LV, Eremenko OA, Shaposhnikova OF, Makarova MS. BILIARY SLUDGE AS THE INITIAL STAGE OF CHOLELITHIASIS. THERAPY AND PREVENTION. Meditsinskiy sovet = Medical Council. 2017;(5):65-69. (In Russ.) https://doi.org/10.21518/2079-701X-2017-5-65-69

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ISSN 2079-701X (Print)
ISSN 2658-5790 (Online)