АДЪЮВАНТНАЯ ГОРМОНОТЕРАПИЯ ПРЕМЕНОПАУЗАЛЬНЫХ ЖЕНЩИН С ER+-РАКОМ МОЛОЧНОЙ ЖЕЛЕЗЫ
Аннотация
Адъювантная эндокринотерапия пременопаузальных пациентов с ER+-раком молочной железы обычно заключается в получении тамоксифена в течение 5 лет. Однако в случаях высокого риска рецидива заболевания возникает необходимость в подавлении (супрессии) функции яичников как основных генераторов эстрогенов, стимулирующих рост и прогрессирование заболевания, обычно с помощью агонистов гонадотропин-рилизинг-гормона. В результате наступившей медикаментозной постменопаузы становится возможным вместе с агонистами ГнРГ использовать не только тамоксифен, но и ингибиторы ароматазы, обладающие большей противоопухолевой активностью.
Об авторах
В. Ф. СЕМИГЛАЗОВ
Научно-исследовательский институт онкологии им. Н.Н. Петрова Минздрава России
Россия
д.м.н., профессор
Россия
д.м.н., профессор
В. В. СЕМИГЛАЗОВ
Первый Санкт-Петербургский государственный университет им. акад. И.П. Павлова
Россия
д.м.н.
Россия
д.м.н.
В. Ю. ЛИФАНОВА
Научно-исследовательский институт онкологии им. Н.Н. Петрова Минздрава России
Россия
Россия
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Рецензия
Для цитирования:
СЕМИГЛАЗОВ В.Ф., СЕМИГЛАЗОВ В.В., ЛИФАНОВА В.Ю. АДЪЮВАНТНАЯ ГОРМОНОТЕРАПИЯ ПРЕМЕНОПАУЗАЛЬНЫХ ЖЕНЩИН С ER+-РАКОМ МОЛОЧНОЙ ЖЕЛЕЗЫ. Медицинский Совет. 2017;(6):156-159. https://doi.org/10.21518/2079-701X-2017-6-156-159
For citation:
SEMIGLAZOV V.F., SEMIGLAZOV V.V., LIFANOVA V.Y. ADJUVANT HORMONE THERAPY ELIGIBILITY OF PREMENOPAUSAL WOMEN WITH ER+ BREAST CANCER. Meditsinskiy sovet = Medical Council. 2017;(6):156-159. (In Russ.) https://doi.org/10.21518/2079-701X-2017-6-156-159
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