Comparative characteristics of associated manifestations in patients with irritable bowel syndrome of different ages
https://doi.org/10.21518/2079-701X-2015-7-72-77
Abstract
The clinical picture of IBS, in addition to gastrointestinal symptoms, is dominated by extraintestinal manifestations (EIM). The study evaluated the incidence and clinical spectrum of EIM using screening for somatoform disorders (SOMS_2) in young and old IBS patients depending on gender and type of IBS. IBS patients for study were divided into 2 groups: younger than 45 years (125 subjects) and older than 45 years (120 subjects), the total number equalling 245 patients. The IM study showed that more than half of patients in both groups experienced "excessive fatigue" and a feeling of "vertigo or instability." 40 to 50% of patients demonstrated polysystemic vegetative dysfunction: "feeling of nausea", "heartbeat", "sweat", "flashes of heat and cold," and so forth. Both groups showed high frequency of pain in different locations. Women suffered from EIM much more often than men. The frequency of separate EIM changed significantly in women with age, which was not observed in men.
About the Authors
M. G. Mnatsakanyan
First Moscow State Medical University named after I.M. Sechenov
Russian Federation
Russian Federation
O. V. Taschyan
First Moscow State Medical University named after I.M. Sechenov
Russian Federation
Russian Federation
A. P. Pogromov
First Moscow State Medical University named after I.M. Sechenov
Russian Federation
Russian Federation
G. M. Dyukova
First Moscow State Medical University named after I.M. Sechenov
Russian Federation
Russian Federation
References
1. Multi-Dimensional Clinical Profile (MDCP): For the Functional Gastrointestinal Disorders 1-st edition. Ed. DROSSMAN D.A. et al. 2015.
2. Maxwell PR, Mendall MA, Kumar D. Irritable bowel syndrome. Lancet, 1997, 350(9092): 1691-1695.
3. Canavan C, West J, Card T. The epidemiology of irritable bowel syndrome. Clinical Epidemiology, 2014, 6: 71-80.
4. Пиманов С.И. Силивончик Н.Н. Римский III консенсус: избранные разделы и комментарии. 2006, Витебск, стр.152.
5. Chey WD, Drossman dA, Johanson JF, Scott C, Panas RM, Ueno R. Safety and patient outcomes with lubiprostone for up to 52 weeks in patients with irritable bowel syndrome with constipation. Aliment Pharmacol Ther., 2012, 35(5): 587-99.
6. Drossman DA. The functional gastrointestinal disorders and the Rome process. Gastroenterology, 2006, 130: 1377-1390.
7. Rief W, Hiller W, Heuser J. SOMS - Das Screening fur Somatoforme Storungen: Manual zum Fragebogen. Bern: Huber; 1997.
8. Ehrenpreis ED Irritable bowel syndrome. 10% to 20% of older adults have symptoms consistent with diagnosis. Geriatrics, 2005, 60(1): 25-8.
9. Talley NJ, O'Keefe EA, Zinsmeister AR, Melton III LI. Prevalance of gastrointestinal symptoms in the elderly: a population-based study. Gastroenterology, 1992, 102: 895-901.
10. Kay L, Jorgensen T, Schultz-Larsen K. Colon related symptoms in a 70 year old Danish population. J Clin Epidemiol, 1993, 46: 1445-9.
11. Minocha A, Johnson WD, Abell TL, Wigington WC. Prevalence, sociodemography, and quality of life of older versus younger patients with irritable bowel syndrome: a population-based study. Dig Dis Sci. 2006 Mar; 51(3): 446-53.
12. Agrawal A, Khan MH, Whorwell PJ. Irritable bowel syndrome in the elderly: An overlooked problem? Dig Liver Dis (2009), doi:10.1016/j. dld.2009.03.011.
13. Kim SE, Chang L. Overlap between functional GI disorders and other functional syndromes: what are the underlying mechanisms? Neurogastroenterol Motil (2012) doi: 10.1111/j.1365-2982.2012.01993.
14. Whitehead William E, Palsson Olafur S, Levy Rona R, Feld Andrew D, Turner Marsha, Von Korff Michael, Comorbidity in Irritable Bowel Syndrome. Am J Gastroenterol, 2007, 102: 2767-2776.
15. Hershfield NB Nongastrointestinal symptoms of irritable bowel syndrome: an office-based clinical survey. Can J Gastroenterol, 2005, 19(4): 231-4.
16. Whitehead WE, Palsson O, Jones KR. Systematic review of the comorbidity of irritable bowel syndrome with other disorders: what are the causes and implications? Gastroenterology, 2002, 122: 1140-56.
17. Sperber Ami D, Dekel, Irritable Bowel Syndrome and Co-morbid Gastrointestinal and Extra-gastrointestinal Functional Syndromes. J Neurogastroenterol Motil, 2010, 16(2): 113-119.
18. Riedl A, Schmidtmann M, Stengel A, et al. Somatic comorbidities of irritable bowel syndrome: a systematic analysis. J Psychosom Res, 2008, 64: 573-582.
19. Matalon A, Kotliroff A, Blumberg Gari, Yaphe J. Kitai E. Non-specific symptoms as clues to changes in emotional well-being. BMC Family Practice, 2011, 12: 77.
20. Triadafilopoulos G, Finlayson M, Grellet C. Bowel dysfunction in postmenopausal women. Women & Health, 1998, 27: 55-66.
21. Heitkemper M, Jarett M, Bond EF, Chang L. Impact of sex and gender on irritable bowel syndrome. Biol Res Nurs, 2003, 5: 56-65.
22. Cain KC, Jarett ME, Burr RL, Rosen S, Hertig VL, Heitkemper MM. Gender differences in gastrointestinal, psychological, and somatic symptoms in irritable bowel syndrome. Dig Dis Sci 2009; 54: 1542-1549.
23. Ruigomez A, Garsia Rodrigues LA, Johansson S, Wallander MA. Is hormone replacement therapy associated with an increased risk of irritable bowel syndrome? Maturitas, 2003, 44: 133-140.
24. Herman J, Pokkunuri V, Braham L, Pimentel M. Gender distribution in irritable bowel syndrome is proportional to the severity of constipation relative to diarrhea. GendMed, 2010, 7: 240-246.
25. Anbardan SJ, Daryani NE, Fereshtehnejad S-M et al. Gender Role in Irritable Bowel Syndrome: A Comparison of Irritable Bowel Syndrome Module (ROME III) Between Male and Female Patients. J Neurogastroenterol Motil, 2012, 18(1): 70-77.
Review
For citations:
Mnatsakanyan MG, Taschyan OV, Pogromov AP, Dyukova GM. Comparative characteristics of associated manifestations in patients with irritable bowel syndrome of different ages. Meditsinskiy sovet = Medical Council. 2015;(7):72-77. (In Russ.) https://doi.org/10.21518/2079-701X-2015-7-72-77
Views:
385
Email this article 