ТРОМБОЦИТОПЕНИЯ У БОЛЬНЫХ МНОГОПРОФИЛЬНОГО СТАЦИОНАРА И ВОЗМОЖНЫЕ ПУТИ ОПТИМИЗАЦИИ ЕЕ ОЦЕНКИ

Анализ распространенности тромбоцитопении в многопрофильном стационаре, где пролечивается около 25 000 больных в год, показывает, что от 1,15 до 1,45% пациентов имеют опасное снижение тромбоцитов менее 100 x 109/л. Так, 40,2% из них (в среднем 127 человек в год) получают гепарин и могут потенциально рассматриваться как больные, подозрительные на гепарининдуцированную тромоцитопению (ГИТ). Своевременное выявление таких пациентов, применение двух правил – 4Т и «100–5–100» – позволяет не пропустить больного с развитием ГИТ, вовремя перейти на альтернативные антикоагулянты и при необходимости прекратить промывание венозных катетеров раствором гепарина. Такая тактика позволяет уменьшить количество пациентов, получающих гепарин и имеющих тромбоцитопению ниже 100 х 109/л, почти в 3 раза как в общебольничных, так и в реанимационных отделениях за 3 года использования указанной тактики.

тромбоцитопения, гепарин-индуцированная тромбоцитопения (ГИТ), лекарственная тромбоцитопения, гепарины, иммунодиагностика, тромбоз, оригинальное Правило экспресс-диагностики ГИТ «100-5-100».

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