Три преимущества торемифена, или Тренд современной гормонотерапии

Е. И. Борисова; С. Л. Гуторов

doi:10.21518/2079-701X-2015-8-60-65

Три преимущества торемифена, или Тренд современной гормонотерапии

Е. И. Борисова, С. Л. Гуторов

https://doi.org/10.21518/2079-701X-2015-8-60-65

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Аннотация

Внедрение торемифена в клиническую практику существенно расширяет возможности современной эндокринотерапии люминальных субтипов рака молочной железы. Торемифен демонстрирует как минимум равную эффективность с тамоксифеном, но при этом имеет более благоприятный спектр побочных эффектов, включая тромбоэмболические осложнения. Данные преимущества позволяют значительно снизить частоту нерационального прекращения терапии. Перспективной представляется также возможность безопасного применения высоких доз торемифена, включая изучаемые режимы предоперационной терапии.

Ключевые слова

рак молочной железы, селективные модуляторы рецепторов эстрогена, торемифен, breast cancer, selective estrogen receptor modulators, toremifene

Об авторах

Е. И. Борисова

Российский онкологический научный центр им. Н.Н. Блохина, Москва
Россия

С. Л. Гуторов

Российский онкологический научный центр им. Н.Н. Блохина, Москва
Россия

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