Таргетные препараты во второй линии противоопухолевой терапии диссеминированного колоректального рака
Аннотация
В течение многих лет колоректальный рак является одним из наиболее распространенных видов злокачественных опухолей в мире. При этом результаты лечения больных метастатическим колоректаль-ным раком на протяжении длительного времени оставались неудовлетворительными. Существенное влияние на улучшение отдаленных результатов лечения больных с метастазами колоректального рака оказало развитие таргетной терапии. В статье изложены основные рекомендации по использованию таргетных препаратов во второй линии терапии диссеминированного колоректального рака, описан механизм действия, эффективность, токсичность, особенности применения. Приведены данные по новым таргетным препаратам, проходящим этап изучения в рамках клинических исследований.
Об авторах
К. А. Воронцова
Российский онкологический научный центр им. Н.Н. Блохина, Москва
Россия
Россия
Е. В. Черноглазова
Российский онкологический научный центр им. Н.Н. Блохина, Москва
Россия
Россия
Г. В. Вышинская
Российский онкологический научный центр им. Н.Н. Блохина, Москва
Россия
Россия
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