The role of erythropoietins in cancer therapy
https://doi.org/10.21518/2079-701X-2018-10-134-139
Abstract
Anemia is a common hematological complication in cancer patients receiving chemotherapy. Reduction of hemoglobin level is accompanied by a significant deterioration in the patients’ life quality. A transfusion of erythrocyte mass is used to rapidly increase the hemoglobin level in case of development of a symptomatic anemia. However, a large range of risks limit the wide use of blood transfusions. Erythropoiesis-stimulating proteins are the drugs that reduce the need for blood transfusions. Treatment with erythropoietins provides a smooth and prolonged rise in the hemoglobin level, the release of fully functional red blood cells into the blood. The use of erythropoietins can significantly improve the quality of life of cancer patients without reducing the effectiveness of chemotherapy.
About the Authors
O. E. Kondratieva
N.N.Blokhin National Medical Research Cancer Centre of Oncology, Federal State Budgetary Institution of the Ministry of Health of Russia
Russian Federation
Moscow
Russian Federation
Moscow
M. E. Abramov
N.N.Blokhin National Medical Research Cancer Centre of Oncology, Federal State Budgetary Institution of the Ministry of Health of Russia
Russian Federation
Moscow
Russian Federation
Moscow
G. V. Vyshinskaya
N.N.Blokhin National Medical Research Cancer Centre of Oncology, Federal State Budgetary Institution of the Ministry of Health of Russia
Russian Federation
Moscow
Russian Federation
Moscow
S. L. Gutorov
N.N.Blokhin National Medical Research Cancer Centre of Oncology, Federal State Budgetary Institution of the Ministry of Health of Russia
Russian Federation
Moscow
Russian Federation
Moscow
E. I. Borisova
N.N.Blokhin National Medical Research Cancer Centre of Oncology, Federal State Budgetary Institution of the Ministry of Health of Russia
Russian Federation
Moscow
Russian Federation
Moscow
E. V. Cherniglazova
N.N.Blokhin National Medical Research Cancer Centre of Oncology, Federal State Budgetary Institution of the Ministry of Health of Russia
Russian Federation
Moscow
Russian Federation
Moscow
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Review
For citations:
Kondratieva OE, Abramov ME, Vyshinskaya GV, Gutorov SL, Borisova EI, Cherniglazova EV. The role of erythropoietins in cancer therapy. Meditsinskiy sovet = Medical Council. 2018;(10):134-139. (In Russ.) https://doi.org/10.21518/2079-701X-2018-10-134-139
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