Modern methods of prevention and treatment of postmenopausal osteoporosis

Abstract

Osteoporosis constitutes one of the major public health problems in Russia and all over the world; this pathology has showed a tendency toward growth in recent decades. In Russia, osteoporosis was detected in 30.5-33.1% of women aged 50 years and older who underwent densitometry examination, and the incidence of proximal femur fracture for persons over the age of 50 years averages to 105.9 per 100 000. Objective of the study: evaluation of the efficacy of osteo activ in the prevention and treatment of postmenopausal osteoporosis. Materials and methods of the study: 58 postmenopausal patients were examined. In addition to general clinical examination, the concentration of total and ionized Ca, as well as vitamin D in blood plasma were determined in all patients. All examined patients were divided into two groups according to the “case-control” principle: the first group (the main group) included 35 patients who were prescribed osteo activ for the purpose of treating and preventing postmenopausal osteoporosis; the second group (the comparison group) included 23 patients, whose diet was corrected in accordance with the daily requirement of calcium and vitamin D. Results of the study: The study showed a significant increase in the calcium and vitamin D concentration in the blood plasma and a decrease in pain syndrome against the background of the therapy in patients of the main group.