Influence of active and passive smoking at pregnancy on expression of an oxidizing stress
https://doi.org/10.21518/2079-701X-2018-21-236-239
Abstract
Objective: definition of indicators of system prooksidanty-antioxidants at active and passive smoking during pregnancy. Material and methods. On the basis of city clinic for women 39 pregnant women on the term of a gestation of 37 weeks are examined. Questioning, rapid test for identification of a kotinin in urine, determination of level of a malon dialdehyde (MDA) and also activities superoxide dismutases (SOD) and catalases is carried out to bloods of surveyed. Patients are divided into 3 groups: I-of 11 smoking pregnant women subject to II-13 to passive smoking at pregnancy, III-control group of 15 women. Results. At patients of I and II groups substantial increase of level MDA in blood serum is noted. Reliable decrease of the activity of SOD of erythrocytes in the I group and insignificant decrease of the activity in II is taped. The indicator of catalase/SOD was statistically higher at active smoking. Conclusion. Active and passive smoking at pregnancy leads to change in prooxidatic and antioxidatic systems.
About the Authors
O. A. Chursina
Federal State Budgetary Educational Institution of Higher Education «Orenburg State Medical University» of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Chursina Olga Andreevna – post-graduate of the Department of Obstetrics and Gynaecology
24 Nevelskaya, Orenburg, 460018
O. D. Konstantinova
Federal State Budgetary Educational Institution of Higher Education «Orenburg State Medical University» of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Konstantinova Olga Dmitrievna – Dr.of Sci. (Med.), Professor, Head of the Department of Obstetrics and Gynaecology
24 Nevelskaya, Orenburg, 460018
S. I. Krasikov
Federal State Budgetary Educational Institution of Higher Education «Orenburg State Medical University» of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Krasikov Sergei Ivanovich – Dr.of Sci.(Med.), Professor, Head of the Department of Chemistry and Pharmaceutical Chemistry
24 Nevelskaya, Orenburg, 460018
A. A. Petrova
Federal State Budgetary Educational Institution of Higher Education «Orenburg State Medical University» of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Petrova Alena Andreevna – Assistant Professor of the Department of Chemistry and Pharmaceutical Chemistry
24 Nevelskaya, Orenburg, 460018
N. I. Kolosova
Federal State Budgetary Educational Institution of Higher Education «Orenburg State Medical University» of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Kolosova Natalia Ivanovna – Senior Lector of the Department of Biophisics and Mathematics
24 Nevelskaya, Orenburg, 460018
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Review
For citations:
Chursina OA, Konstantinova OD, Krasikov SI, Petrova AA, Kolosova NI. Influence of active and passive smoking at pregnancy on expression of an oxidizing stress. Meditsinskiy sovet = Medical Council. 2018;(21):236-239. (In Russ.) https://doi.org/10.21518/2079-701X-2018-21-236-239
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