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Steatorrhea in young children: what to do?

https://doi.org/10.21518/2079-701X-2019-2-124-130

Abstract

Making sure that the child is absorbing properly the main nutrients such as proteins, fats, carbohydrates, and vitamins, macro- and micronutrients is a key influencer when it comes to the harmonious growth and development. In infants, triglycerides digestion starts in the stomach, where three lipases – human milk, gastric and lingual lipases – split triglycerides. The participation of breast milk lipase stimulated by bile salts in the duodenum in splitting fats is an important feature of digestion in breastfed babies. The absorption of fatty acids differs depending on the length of the carbon chain and the location of the fatty acid in the glycerol molecule. Short-chain and medium-chain fatty acids, as well as glycerine, choline are hydrophilic compounds, which are absorbed without pancreatic lipase and bile acids, directly into the blood, bypassing the lymphatic system. The specific configuration of human milk triglycerides improves the absorption of fatty acids. In situations where lipids digestion or absorption appears impaired, one may talk of steatorrhea. If young children have type I steatorrhea (the presence of neutral fat in stool), it is first required to exclude absolute exocrine pancreatic insufficiency: cystic fibrosis, Shwachman-Diamond syndrome, Pearson syndrome, isolated lipase deficiency (Sheldon – Ray syndrome), etc. Type II steatorrhea (excretion of fatty acids in stool) is not a specific symptom of certain diseases, but is often observed in the small intestine pathology.

About the Authors

I. N. Zakharova
Federal State Budgetary Educational Institution of Additional Professional Education «Russian Medical Academy of Continuing Professional Education» of the Ministry of Health of the Russian Federation
Russian Federation

Zakharova Irina Nikolaevna – Dr. of Sci. (Med.), Professor, Speransky Chair of Paediatrics with Course of Polyclinic Paediatrics

125993, Moscow, Barrikadnaya St., 2/1, b. 1



N. G. Sugyan
Federal State Budgetary Educational Institution of Additional Professional Education «Russian Medical Academy of Continuing Professional Education» of the Ministry of Health of the Russian Federation; State Budgetary Healthcare Institution of Moscow «Children’s City Outpatient Clinic No 133 of Moscow Health Department»
Russian Federation

Sugyan Narine Grigoryevna – Cand. of Sci. (Med.), Associate Professor, Speransky Chair of Paediatrics with Course of Polyclinic Paediatrics, Federal State Budgetary Educational Institution of Additional Professional Education «Russian Medical Academy of Continuing Professional Education» of the Ministry of Health of the Russian Federation; Head of Consultative and Diagnostic Department; State Budgetary Healthcare Institution of Moscow «Children’s City Outpatient Clinic No 133 of Moscow Health Department»

125993, Moscow, Barrikadnaya St., 2/1, b. 1, 

125445, Moscow, Smolnaya St., 55



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For citations:


Zakharova IN, Sugyan NG. Steatorrhea in young children: what to do? Meditsinskiy sovet = Medical Council. 2019;(2):124-130. (In Russ.) https://doi.org/10.21518/2079-701X-2019-2-124-130

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