New prospects for local etiotropic treatment of acute respiratory viral infections
https://doi.org/10.21518/2079-701X-2019-8-105-108
Abstract
According to WHO, the respiratory system diseases are currently inside the ten most common pathologies. The modern strategy for treating influenza and ARVI gives priority to the antiviral and immunostimulating agents, but the symptomatic drugs, which include preparations based on silver and its compounds, also play an important role. The large positive experience in using silver preparations supported by numerous clinical studies shows their high efficacy and satisfactory safety profile in the treatment of infectious and inflammatory diseases of the nose and upper respiratory tract in children and adults.
About the Authors
A. A. Krivopalov
Federal State Budgetary Institution Federal State Budgetary Institution «Saint-Petersburg ENT and Speech Research Institute» of the Ministry of Healthcare of the Russian Federation
Russian Federation
Dr. of Sci. (Med.), Senior Researcher, Federal State Budgetary Institution «SaintPetersburg ENT and Speech Research Institute» of the Ministry of Healthcare of the Russian Federation
Russian Federation
Dr. of Sci. (Med.), Senior Researcher, Federal State Budgetary Institution «SaintPetersburg ENT and Speech Research Institute» of the Ministry of Healthcare of the Russian Federation
V. A. Shatalov
Federal State Budgetary Institution Federal State Budgetary Institution «Saint-Petersburg ENT and Speech Research Institute» of the Ministry of Healthcare of the Russian Federation
Russian Federation
Resident Medical Practitioner, ENT Surgery for adults, Federal State Budgetary Institution «Saint-Petersburg ENT and Speech Research Institute» of the Ministry of Healthcare of the Russian Federation
Russian Federation
Resident Medical Practitioner, ENT Surgery for adults, Federal State Budgetary Institution «Saint-Petersburg ENT and Speech Research Institute» of the Ministry of Healthcare of the Russian Federation
S. V. Shervashidze
Federal State Budgetary Institution Federal State Budgetary Institution «Saint-Petersburg ENT and Speech Research Institute» of the Ministry of Healthcare of the Russian Federation
Russian Federation
Clinical Intern, Federal State Budgetary Institution «Saint-Petersburg ENT and Speech Research Institute» of the Ministry of Healthcare of the Russian Federation
Russian Federation
Clinical Intern, Federal State Budgetary Institution «Saint-Petersburg ENT and Speech Research Institute» of the Ministry of Healthcare of the Russian Federation
References
1. Newsletter No. 310 (July 2015). WHO. Data Bank of the Global Health Observatory. Available at: http:// www.who.int/gho/database/en/.] (In Russ).
2. Bank of documents. Ministry of Health of the Russian Federation. Available at: http://old.rosminzdrav.ru/ docs.] (In Russ).
3. Kryuchko, T.A., Kushnereva, T.V., Ostapenko, V.P., Kolenko, I.A. Problem questions of outpatient management of children with acute respiratory viral infections. Sovremennaya Pediatriya. 2014;8(64):65.] (In Russ).
4. Bartlett J. Respiratory tract infections: pract. handbook on the diagnosis and treatment of respiratory tract infections; Translated from English M.; SPb: BINOM - Nevsky dialect, 2000. Available at: http:// www.who.int/gho/database/ru/.] (In Russ).
5. Ryazantsev S.V., Khmelnitskaya N.M., Tyrnova E.V. The role of mucous membrane in protecting the ENT organs from potentially pathogenic antigenic factors. Vestn. Otorhinolar, 2000;3:60-64.] (In Russ).
6. Zhukova L. Differential diagnosis, treatment and prevention of acute respiratory viral infections. Vrach. 2010;10:2-6.] (In Russ).
7. Krivopalov A.A., Yanov Yu.K., Astaschenko S.V., Scherbuk A.Yu., Artyushkin S.A., Vakhrushev S.G., Piskunov IS, Piskunov VS, Tuzikov N.A. Demographic and clinical-epidemiological features of otogenic intracranial complications at the present stage. Rossiyskaya Otorinolaringologiya. 2016;80(1):48-61.] (In Russ).
8. Svistushkin V.M., Nikiforova G.N., Vlasova N.P. The possibilities of treatment of patients with acute respiratory viral infections at the present stage. Lechaschiy Vrach. 2013;1:52.] (In Russ).
9. Khavkin A.I., Zhikhareva N.S. Therapy for antibiotic-associated dysbiosis. RMJ. 2006;14(19):1386–1389.] (In Russ).
10. Trevors J.T. Silver resistance and accumulation in bacteria. Enzyme Microb Technol. 1987;9:331-333.
11. Batarseh K.I. Anomaly and correlation of killing in the therapeutic properties of silver (I) chelation with glutamic and tartaric acids. J Antimicrob Chemother. 2004 Aug;54(2):546-548.
12. Wells T.N., Scully P., Paravicini G., Proudfoot A.E., Payton M.A. Mechanism of irreversible inactivation of phosphomannose isomerases by silver ions and flamazine. Biochemistry. 1995;34(24):7896-903.
13. Savadyan E.Sh., Melnikova V.M., Belikov G.P. Current trends in the use of silver-containing antiseptics. Antibiotiki i Khimioterapiay. 1989;11(34):874-878.] (In Russ).
14. Kanner E.V., Usenko D.V., Maksimov M.L., Gorelova E.A. Current approaches to the treatment of acute rhinopharyngitis in children. RMJ. 2014;21:1541–1543.] (In Russ).
15. Kulskiy P.A. Silver water. K.: Nauk. Dumka, 1987.] (In Russ).
16. Grigoryeva L.V. Sanitary bacteriology and virology of water bodies. M.: Medicine, 1975.] (In Russ).
17. Coward J.E., Carr H.S., Rosenkranz H.S. Silver sulfadiazine: effect on the ultrastructure of Pseudomonas aeruginosa. Antimicrob Agents Chemother. 1973 May;3(5):621-624.
18. Wright J.B., Lam K., Hansen D., Burrell R.E. Efficacy of topical silver against fungal burn wound pathogens. Am J Infect Control. 1999 Aug;27(4):344-350.
19. Scherbakov A. B., Korchak G.I., Surmasheva E.V., Skorokhod I.M., Mihienkova A.I. Silver preparations: yesterday, today, tomorrow. Farmatsevt. Zhurn. 2006;5:45-57.] (In Russ).
20. Morrill K., May K., Leek D., Langland N., Jeane L.D., Ventura J., Skubisz C., Scherer S., Lopez E., Crocker E., Peters R., Oertle J., Nguyen K., Just S., Orian M., Humphrey M., Payne D., Jacobs B., Waters R., Langland J. Spectrum of antimicrobial activity associated with ionic colloidal silver. J Altern Complement Med. 2013 Mar;19(3):224-31. doi: 10.1089/acm.2011.0681/
21. Sichinava I.V. Protargol in the treatment of rhinosinusitis in children. RMJ. 2015;23(14):844-846.] (In Russ).
Review
For citations:
Krivopalov AA, Shatalov VA, Shervashidze SV. New prospects for local etiotropic treatment of acute respiratory viral infections. Meditsinskiy sovet = Medical Council. 2019;(8):105-108. (In Russ.) https://doi.org/10.21518/2079-701X-2019-8-105-108
Views:
900
Email this article 