Meditsinskiy sovet = Medical Council
Meditsinskiy sovet

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ISSN 2658-5790 (Online)

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Comorbid infections in rheumatic diseases (according to FSBI RIR named after V.A. Nasonova)

D. V. Bukhanova, B. S. Belov, G. M. Tarasova, S. K. Soloviev, L. P. Ananyeva, T. V. Popkova, A. V. Gordeev, Yu. V. Muravyov, S. I. Glukhova

https://doi.org/10.21518/2079-701X-2019-9-86-91

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Abstract

Aim. Study of spectrum, frequency and risk factors of comorbid infections in rheumatic diseases (RD) in the stationary contingent of patients hospitalized in the FSBI RIR named after V.A. Nasonova within 1 year.

Patients and methods. The study included 245 patients with RD: 122 patients suffered from rheumatoid arthritis, 62 - systemic lupus erythematosus, 61 - systemic scleroderma. All patients were interviewed by a doctor-researcher and filled in a questionnaire. If necessary, additional information was obtained during the analysis of medical records.

Results. In the spectrum of infections in patients with RD, respiratory tract and ENT infections prevailed. The frequency of serious infections (SI) during RD in the studied cohort was 23.7–38.1%. The frequency of certain infections, including SI, is influenced by the duration and variant of RD, comorbid diseases and immunosuppressive therapy.

Conclusions: the data obtained indicate the importance of infections in rheumatology. A high percentage of RD exacerbation against the background of infection, the prevalence of respiratory tract infections, including SI, dictate the need for vaccine prophylaxis at the early stages of RD.

Keywords

infections, rheumatoid arthritis, systemic lupus erythematosus, systemic scleroderma, pneumonia

About the Authors

D. V. Bukhanova

Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».
Russian Federation

Postgraduate Student of the Laboratory for the Study of Comorbid Infections and Monitoring of Drug Therapy Safety of the Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».

B. S. Belov

Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».
Russian Federation

Dr. of Sci. (Med), Head of the Laboratory for the Study of Comorbid Infections and Monitoring of Drug Therapy Safety of the Federal State Budge tary Institution «Research Institute of Rheu matology named after V.A. Nasonova».

G. M. Tarasova

Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».
Russian Federation

Cand. of Sci. (Med.), Senior Researcher of the Laboratory for Comorbid Infections and Monitoring of Drug Therapy Safety of the Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».

S. K. Soloviev

Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».
Russian Federation

Dr. of Sci. (Med), Professor, Head of the Laboratory of Intensive Therapy Methods of the Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».

L. P. Ananyeva

Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».
Russian Federation

Dr. of Sci. (Med), Professor, Head of the Laboratory of Microcirculation and Inflammation of the Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».

T. V. Popkova

Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».
Russian Federation

Dr. of Sci. (Med), Head of the Laboratory of Systemic Rheumatic Diseases of the Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».

A. V. Gordeev

Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».
Russian Federation

Dr. of Sci. (Med), Professor, Head of the Early Arthritis Laboratory of the Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».

Yu. V. Muravyov

Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».
Russian Federation

Dr. of Sci. (Med), Professor, Leading Researcher of the Comorbid Infections and Drug Therapy Safety Monitoring Laboratory of the Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».

S. I. Glukhova

Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».
Russian Federation

Cand. of Sci. (Physics and Mathematics.), Senior Researcher of the Laboratory of Medical and Social Problems of Rheumatology of the Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».

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For citations:

Bukhanova DV, Belov BS, Tarasova GM, Soloviev SK, Ananyeva LP, Popkova TV, Gordeev AV, Muravyov YV, Glukhova SI. Comorbid infections in rheumatic diseases (according to FSBI RIR named after V.A. Nasonova). Meditsinskiy sovet = Medical Council. 2019;(9):86-91. (In Russ.) https://doi.org/10.21518/2079-701X-2019-9-86-91

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ISSN 2079-701X (Print)
ISSN 2658-5790 (Online)

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About the Authors

D. V. Bukhanova
Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».
Russian Federation

Postgraduate Student of the Laboratory for the Study of Comorbid Infections and Monitoring of Drug Therapy Safety of the Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».

B. S. Belov
Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».
Russian Federation

Dr. of Sci. (Med), Head of the Laboratory for the Study of Comorbid Infections and Monitoring of Drug Therapy Safety of the Federal State Budge tary Institution «Research Institute of Rheu matology named after V.A. Nasonova».

G. M. Tarasova
Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».
Russian Federation

Cand. of Sci. (Med.), Senior Researcher of the Laboratory for Comorbid Infections and Monitoring of Drug Therapy Safety of the Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».

S. K. Soloviev
Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».
Russian Federation

Dr. of Sci. (Med), Professor, Head of the Laboratory of Intensive Therapy Methods of the Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».

L. P. Ananyeva
Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».
Russian Federation

Dr. of Sci. (Med), Professor, Head of the Laboratory of Microcirculation and Inflammation of the Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».

T. V. Popkova
Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».
Russian Federation

Dr. of Sci. (Med), Head of the Laboratory of Systemic Rheumatic Diseases of the Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».

A. V. Gordeev
Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».
Russian Federation

Dr. of Sci. (Med), Professor, Head of the Early Arthritis Laboratory of the Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».

Yu. V. Muravyov
Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».
Russian Federation

Dr. of Sci. (Med), Professor, Leading Researcher of the Comorbid Infections and Drug Therapy Safety Monitoring Laboratory of the Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».

S. I. Glukhova
Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».
Russian Federation

Cand. of Sci. (Physics and Mathematics.), Senior Researcher of the Laboratory of Medical and Social Problems of Rheumatology of the Federal State Budgetary Institution «Research Institute of Rheumatology named after V.A. Nasonova».

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