Treating a patient with lower back pain
https://doi.org/10.21518/2079-701X-2019-12-25-32
Abstract
Back pain is one of the most common causes of medical treatment and temporary disability, which makes the problem of rational therapy particularly relevant. The main means of treatment of acute nonspecific back pain (NBS) are nonsteroidal anti-inflammatory drugs (NSAIDs) and myorelaxants. A number of studies have been conducted to evaluate the efficacy and safety of NSAIDs such as dexketoprofen (Dexalgin), which is equivalent to inhibit cyclooxygenase-1 (COX-1) and COX-2, and nimesulide (Nimesil), which preferential inhibits COX-2. The clinical efficacy of dexketoprofen in NBS, osteoarthritis (OA) of different localization was shown. The scheme of administration of Dexalgin is used - intramuscular injections of 2 ml (50 mg) for 1-2 days, then oral administration of 1 tablet or sachet (25 mg) 3 times a day for 3-5 days. The efficiency of Nimesil administration in OA in patients with high risk of complications from the gastrointestinal tract (GIT) is shown. The scheme of nimesil - 1 sachet (100 mg) is used 2 times a day for no more than 15 days. Perhaps the combined appointment of Dexalgin - the first 2 days of injection, then - the transition to oral nimesil 7-10 days.
About the Author
O. A. Shavlovskaya
Federal State Autonomous Educational Institution of Higher Education First Moscow State Medical University named after I.M. Sechenov of the Ministry of Health of the Russian Federation (Sechenov University)
Russian Federation
Russian Federation
Shavlovskaya Olga Aleksandrovna - Dr. of Sci. (Med.), a lead researcher of Research Unit of Neurology, Biomedical Science and Technology Park.
119991, Moscow, B. Pirogovskaya St., 6, Bldg. 1; Tel.: +7(495) 609-14-00
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For citations:
Shavlovskaya OA. Treating a patient with lower back pain. Meditsinskiy sovet = Medical Council. 2019;(12):25-32. (In Russ.) https://doi.org/10.21518/2079-701X-2019-12-25-32
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