1% film-forming terbinafine solution in therapy in patients with long-lasting foot mycoses
https://doi.org/10.21518/2079-701X-2019-12-132-135
Abstract
Topical antimycotic agents are used in the treatment of foot mycosis. Numerous studies have shown the efficacy of terbinafine. Fungistatic activity of the medication is provided by blockade of action of squalene epoxidase enzyme and subsequent inhibition of squalene transformation into squalene epoxy. Further accumulation of squalene inside the fungal cell with its subsequent rupture and death occurs. Various medicinal forms of terbinafine have been developed, which can be used at different stages and at different forms of foot mycosis. The present study shows high efficacy and safety of 1% film-forming solution of Lamisil UNO in therapy in patients suffering from foot mycosis for a long time. The unique form of the drug allows limiting treatment to one application.
About the Authors
I. V. Hamaganova
Federal State Budgetary Educational Institution of Higher Education «Russian National Research Medical University named after N.I. Pirogov» of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Hamaganova Irina Vladimirovna - Dr. of Sci. (Med), Professor of the Department of Skin Diseases and Cosmetology of the Faculty of Additional Professional Education.
117997, Moscow, Ostrovityanova St., 1; tel: +7 (495) 954-53-97A. A. Tsykin
Federal State Budgetary Educational Institution of Higher Education «Russian National Research Medical University named after N.I. Pirogov» of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Tsykin Alexey Alexandrovich - Cand. of Sci. (Med), Associate Professor of the Department of Skin Diseases and Cosmetology of the Faculty of Additional Professional Education.
117997, Moscow, Ostrovityanova St., 1; tel: +7 (495) 954-53-97
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Review
For citations:
Hamaganova IV, Tsykin AA. 1% film-forming terbinafine solution in therapy in patients with long-lasting foot mycoses. Meditsinskiy sovet = Medical Council. 2019;(12):132-135. (In Russ.) https://doi.org/10.21518/2079-701X-2019-12-132-135
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