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Probiotics, prebiotics and metabiotics in the management of microecological bowel disorders

https://doi.org/10.21518/2079-701X-2015-13-94-99

Abstract

Based on the evaluation of the composition and functions of the intestinal microflora and mechanism for the realization of "microflora - macroorganism" relationship, as well as causes of intestinal micro-ecological disorders, the need and options for their timely correction are demonstrated. The main principles of treatment and preventive actions are presented. Taking into account recent classifications and requirements for drugs, as well as evaluation of the mechanism of action and therapeutic options, the main groups of drugs (pro-, prebiotics and metabiotics) used in the management of gut microbiota in disease are described.

About the Author

M. D. Ardatskaya
Teaching and Research Medical Center of the Russian Federation Presidential Administration
Russian Federation


References

1. Готтшалк Г. Метаболизм бактерий. Перевод с английского, Москва, «МИР», 1982 г.

2. Ардатская М.Д. Клиническое значение корот-коцепочечных жирных кислот при патологии желудочно-кишечного тракта. Автореф. Докт. дисс. Москва 2003 г. 48 с.

3. Short Chain Fatty Acids. Congress Short Report Falk Symposium, comp. by Scheppach W., Strasbourg, 1993, 50 p.

4. Захаренко С.М., Суворов А.Н. Антибиотики, пробиотики, пребиотики: друзья или враги? Consilium medicum, 2009, 8(11): 47-51.

5. Калмыкова А.И., Селятицкая В.П, Пальчикова Н.А., Бгатова Н.П. Клеточные и системные механизмы действия пробиотиков. Новосибирск, 2007, 280 с.

6. Потапов А.С., Пахомовская Н.Л., Полякова С.И. Применение пробиотиков врачами общей практики. Consilium medicum. Гастроэнтерология, 2007, 1: 54-58.

7. Щекина М.И. Роль пробиотиков в коррекции дисбиотических нарушений. Consilium medicum. Приложение. Гастроэнтерология, 2009, 2: 36-42

8. Захаренко С.М. Представление врачей о современных пробиотиках. Consilium medicum. Приложение. Гастроэнтерология, 2011, 8(13): 51-56.

9. Sazawal SG, Hiremath U, Dhingra P, Malik P, Deb S, Black RE. Efficacy of probiotics in prevention of acute diarrhoea: a meta-analysis of masked randomised, placebo-controlled trials. Lancet Infect Dis, 2006, 6: 374-82.

10. Floch MH, Madsen KK, Jenkins DJ, et al. Recommendations for probiotic use. J Clin Gastroenterol, 2006, 40: 275-8.

11. Ouigley EMM, Flourie B. Probiotics and irritable bowel syndrome: a rationale for their use and an assessment of the evidence to date. Neurogastroenterol Motil, 2007, 19: 166-72.

12. Mallon P, McKay D, Kirk S, Gardiner K. Probiotics for induction of remission in ulcerative colitis. Cochrane Database Syst Rev, 2007, (4):CD005573.

13. Tong JL, Ran ZH, Shen J, Zhang CX, Xiao SD. Metaanalysis: the effect of supplementation with probiotics on eradication rates and adverse events during Helicobacter pylori eradication therapy Aliment Pharmacol Ther, 2007, 25: 155-68.

14. Ардатская М.Д. Клиническое применение пищевых волокон. Методическое пособие. М:4ТЕ Арт, 2011. 48 с.

15. Hamer HM et al. Review article: the role of butyrate on colonic function. Aliment Pharmacol Ther, 2008, 27: 104-119.

16. Ардатская М.Д. Масляная кислота и инулин в клинической практике. Теоретические аспекты и возможности клинического применения: [пособие].- М.:Форте принт, 2014. с. 64.

17. Vanhoutvin SA, Troost Fj, Kilkens TO, Lindsey PJ, Hamer HM, Jonkers DM, Venema K, Brummer RJThe effects of butyrate enemas on visceral perception in healthy volunteers. Neurogastroenterol Motil, 2009, 21(9): 952-e 76.

18. Scarpellini E et al. Efficacy of butyrate in the treatment of diarrhoea-predominant irritable bowel syndrome. Digestive and Liver Disease, 2007, 1: 19-22.

19. Assisi RF. Combined butyric acid/mesalazine treatment in ulcerative colitis with mild-moderate activity. Results of a multicentre pilot study. Minerva Gastroenterol Dietol., 2008 Sep, 54(3): 231-8.

20. Sabatino A Di et al. Efficacy of butyrate in the treatment of mild to moderate Crohn's disease. Digestive and Liver Disease Supplements, 2007, 1: 31-35.

21. Krokowicz L et al. Microencapsulated sodium butyrate administered to patients with divertic-ulosis decrease incidence of diverticulitis - a prospective randimized study. Int J Colorectal Dis, 2014, 29: 387-393.

22. Berni Canani R et al. Butyrate effects at the intestinal and extraintestinal level. World J Gastroenterol, 2011.

23. Опыт применения препарата Закофальк в различных областях гастроэнтерологии. Сборник научно-практических работ. Под ред. МД. Ардатской. М.: 4ТЕ Арт, 2013. 64 с.


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For citations:


Ardatskaya MD. Probiotics, prebiotics and metabiotics in the management of microecological bowel disorders. Meditsinskiy sovet = Medical Council. 2015;(13):94-99. (In Russ.) https://doi.org/10.21518/2079-701X-2015-13-94-99

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