The genome-wide analysis of the vitamin D receptor binding sites evidences a wide range of potential therapeutic applications of vitamin D
https://doi.org/10.21518/2079-701X-2016-1-12-21
Abstract
The article presents the results of the genome-wide bioinformatic analysis of the vitamin D receptor interactions with the human genome DNA. Using a biological system assay, biological roles of proteins were analyzed that are specifically associated with the impact of VDR receptor. Systematization of the biological roles of vitamin D opens broad and previously unexplored perspectives for pediatric applications of vitamin D preparations for the prevention and treatment of a wide range of diseases starting from the fetal stage and early childhood.
About the Authors
O. A. Gromova
Ivanovo State Medical Academy
Russian Federation
Russian Federation
I. Y. Torshin
Moscow Institute of Physics and Technology
Russian Federation
Russian Federation
V. B. Spirichev
Scientific Research Institute of Nutrition
Russian Federation
Russian Federation
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Review
For citations:
Gromova OA, Torshin IY, Spirichev VB. The genome-wide analysis of the vitamin D receptor binding sites evidences a wide range of potential therapeutic applications of vitamin D. Meditsinskiy sovet = Medical Council. 2016;1(1):12-21. (In Russ.) https://doi.org/10.21518/2079-701X-2016-1-12-21
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