Preview

Meditsinskiy sovet = Medical Council

Advanced search

Difficult patient. Management of resistant constipation

https://doi.org/10.21518/2079-701X-2019-14-88-92

Abstract

Just like the vast majority of diseases, constipation is now associated with civilization and urbanization. According to epidemiological data, up to 30% of the adult population of economically developed countries suffer from this nosology, among which women predominate. It is known that only one of four patients suffering from stool retention visit a specialist. The rest confine themselves to the advice of friends, reading of popular medical literature or consulting a pharmacist at the pharmacy. Thus, only 25% of our patients receive medical care (we cannot talk about quality, nevertheless, the care is medical), and 75%, as a rule, only periodically try to set off this condition. Constipation is dangerous as it may cause the development of complications: secondary colitis, proctosigmoiditis, hemorrhoids, anal fissures, paraproctitis and the most threatening disease – colorectal cancer. Therapy for constipation should first begin with lifestyle changes. The irritating agents that enhance secretion are the drugs that are most frequently used, because they very quickly and reliably achieve the effect. Thus, among the most commonly used and effective ones are sodium picosulfate (Regulax®) preparations.

About the Authors

E. I. Sas
Federal State Budgetary Military Educational Institution of Higher Education «Military Medical Academy named after S.M. Kirov» of the Ministry of Defence of the Russian Federation; Federal State Budgetary Educational Institution of Higher Education «St. Petersburg State Pediatric Medical University» of the Ministry of Health of the Russian Federation
Russian Federation

Sas Evgeny Ivanovich, Dr. of Sci. (Med.), Professor, the 2nd Chair for Therapy (Continuing Medical Education), Federal State Budgetary Military Educational Institution of Higher Education «Kirov Military Medical Academy» of the Ministry of Defence of the Russian Federation

194044, Saint-Petersburg, 6, Akademika Lebedev Street, 

194100, Saint-Petersburg, 2, Litovskaya St.

 

 



V. В. Grinevich
Federal State Budgetary Military Educational Institution of Higher Education «Military Medical Academy named after S.M. Kirov» of the Ministry of Defence of the Russian Federation
Russian Federation

Grinevich Vladimir Borisovich, Dr. of Sci. (Med.), Professor, Colonel of Military Medical Service, Head of the 2nd Chair for Therapy (Continuing Medical Education), Federal State Budgetary Military Educational Institution of Higher Education «Kirov Military Medical Academy» of the Ministry of Defence of the Russian Federation; Vice-President Gastroenterological Scientific Society of Russia (NOGR) – President of Pancreatic Club

194044, Saint-Petersburg, 6, Akademika Lebedev Street

 



References

1. Mayev I., Samsonov A., Dicheva D., Andreyev D. Оbstipation syndrome. Meditsinskiy vestnik MVD = MIA Medical Bulletin. 2012;(4):42–45. (In Russ.) Available at: https://elibrary.ru/item.asp?id=17861889.

2. De Giorgio R., Ruggeri E., Stanghellini V., Eusebi L.H., Bazzoli F., Chiarioni G. Chronic constipation in the elderly: a primer for the gastroenterologist. BMC Gastroenterol. 2015;15:130. doi: 10.1186/s12876-0150366-3.

3. Maev I.V., Dicheva D.T., Andreev D.N., Berezutskaya O.E., Golovkina N.L., Gurtovenko I.Yu. Towards the treatment of constipation in elderly patients. Moscow; 2012: 95–101. (In Russ.) Available at: https://elibrary.ru/item.asp?id=21254438.

4. Lembo A., Camilieri M. Chronic constipation. N Engl J Med. 2003;349(14):1360-1368. doi: 10.1056/NEJMra020995.

5. Johanson I.F. Review of the Treatment Options for Chronic Constipation. MedGenMed. 2007;9(2):25. Available at: https://www.ncbi.nlm.nih.gov/pubmed/17955081.

6. Cash B.D., Chey W.D. The role of serotonergic agents in the treatment of patients with primary chronic constipation. Aliment. Pharmacol. Ther. 2005;22:1047–1060. doi: 10.1111/j.1365-2036.2005.02696.x

7. Drossman D.A. The functional gastrointestinal disorders and the Rome III process. Gastroenterology. 2006;130(5):1377–1390. doi: 10.1053/j.gastro.2006.03.008.

8. Longstreth G.F., Thompson W.G., Chey W.D., Houghton L.A., Mearin F., Spiller R.C. Functional bowel disorders. Gastroenterology. 2006;130(5):1480–1491. doi: 10.1053/j.gastro.2005.11.061.

9. American College of Gastroenterology Chronic Constipation Task Force. An evidence-based approach to the management of chronic constipation in North America. Am J Gastroenterol. 2005;100(Suppl 1):S1-4. doi: 10.1111/j.1572-0241.2005.50613_1.x.

10. Wald A. Chronic constipation: advances in management. Neurogastroenterol Motil. 2007;19(1):4-10. doi: 10.1111/j.1365-2982.2006.00835.x.

11. Lewis S.J., Heaton K.W. Stool form scale as a useful guide to intestinal transit time. Scand J Gastroenterol. 1997;32(9):920-924. doi: 10.3109/00365529709011203.

12. Velio P., Bassotti G. Chronic idiopathic constipation: pathophysiology and treatment. J Clin Gastroenterol. 1996;22(3):190-196. doi: 10.1097/00004836-199604000-00008.

13. Tack J., Muller-Lissner S., Stanghellini V., Boeckxstaens G., Kamm M.A., Simren M., Galmiche J.P., Fried M. Diagnosis and treatment of chronic constipation – a European perspective. Neurogastroenterol Motil. 2011 Aug;23(8):697-710. doi: 10.1111/j.1365-2982.2011.01709.x.

14. Ford A.C., Suares N.C. Effect of laxatives and pharmacological therapies in chronic idiopathic constipation: systematic review and meta-analysis. Gut. 2011;60(2):209–218. doi: 10.1136/gut.2010.227132.

15. Cash B.D., Lacy B.E. Systematic review: FDAapproved prescription medications for adults with constipation. Gastroenterol Hepatol (N Y). 2006;2(10):736–749. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358085/


Review

For citations:


Sas EI, Grinevich VВ. Difficult patient. Management of resistant constipation. Meditsinskiy sovet = Medical Council. 2019;(14):88-92. (In Russ.) https://doi.org/10.21518/2079-701X-2019-14-88-92

Views: 680


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2079-701X (Print)
ISSN 2658-5790 (Online)