Diabetic polyneuropathy: effectiveness of therapy with Actovegin

Abstract

The article is devoted to the treatment of diabetic neuropathy with Actovegin. Diabetes mellitus is widespread all around the world. Complications of the disease include nephropathy, retinopathy, and diabetic neuropathy. The most common and well known form of diabetic neuropathy is distal neuropathy. In recent years, new data was obtained on the effectiveness of treatment of distal neuropathy with neuroprotector Actovegin which exerts insulin-like effect and does not inhibit glucose transport. Actovegin was shown to be effective for distal neuropathy therapy, according to the two studies described. 6 months of Actovegin therapy demonstrated the following positive changes: effect on neuropathic symptoms, lower vibration sensitivity thresholds, higher peripheral nerve conduction velocity, reduced severity of pain and pain-free walking distance increase.